LYNCH SENDROMUNDA PROFİLAKTİK CERRAHİ: NE ZAMAN VE NASIL? GÜNCEL YAKLAŞIMLAR VE LİTERATÜR DERLEMESİ

Akin, Emrah; Altintoprak, Fatih; Dulger, Ugur Can

doi:10.36516/jocass.2021.70

LYNCH SENDROMUNDA PROFİLAKTİK CERRAHİ: NE ZAMAN VE NASIL? GÜNCEL YAKLAŞIMLAR VE LİTERATÜR DERLEMESİ

Emrah AKIN, (Sakarya Üniversitesi, Eğitim ve Araştırma ve Hastanesi, Genel Cerrahi Anabilim Dalı, Sakarya, Türkiye)

Ugur Can Dulger, (Sakarya Üniversitesi, Eğitim ve Araştırma ve Hastanesi, Genel Cerrahi Anabilim Dalı, Sakarya, Türkiye)

Fatih ALTINTOPRAK (Sakarya Üniversitesi, Tıp Fakültesi, Genel Cerrahi Anabilim Dalı, Sakarya, Türkiye)

Çukurova Anestezi ve Cerrahi Bilimler Dergisi

6 2

Yıl: 2021 Cilt: 4 Sayı: 1 Sayfa Aralığı: 37 - 44 Metin Dili: Türkçe DOI: 10.36516/jocass.2021.70 İndeks Tarihi: 07-09-2022

LYNCH SENDROMUNDA PROFİLAKTİK CERRAHİ: NE ZAMAN VE NASIL? GÜNCEL YAKLAŞIMLAR VE LİTERATÜR DERLEMESİ

Öz:

Lynch sendromu; kolorektal kansere dönüşen soliter adenomlar ve ekstra-kolonik manifestasyonlarla karakterize, otozomal dominant kalıtımlı bir kanser predispozan sendromdur. Sendromun tanısı klinik bulgular, patolojik özellikler, aile öyküsü ve genetik testler ile koyulabilir. Lynch Sendromu riski altında olan bireylerde tarama çalışmalarına 20’ li yaşlardan itibaren başlanmalı, mutasyon pozitif taşıyıcılarında yıllık olarak devam edilmeli ve belli şartların varlığında da profilaktik cerrahi gündeme alınmalıdır.

Anahtar Kelime: LYNCH sendromu herediter polipozis sendromu profilaktik cerrahi

PROPHYLACTIC SURGERY IN LYNCH SYNDROME: WHEN AND HOW? UPDATE AND LITERATURE REVIEW

Öz:

Lynch syndrome; It is an autosomal dominant inherited cancer predisposing syndrome, characterized by solitary adenomas and extra- colonic manifestations transforming into colorectal cancer. The diagnosis of the syndrome could made by clinical findings, pathological features, family history and genetic tests. Surveillance studies should be started in individuals at risk of Lynch Syndrome from the age of 20, it should be continued annually in mutation positive carriers and prophylactic surgery should also be included in the presence of certain conditions.

Anahtar Kelime: LYNCH syndrome herediter polyposis syndrome prophylactic surgery

Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık

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APA	Akin E, Dulger U, Altintoprak F (2021). LYNCH SENDROMUNDA PROFİLAKTİK CERRAHİ: NE ZAMAN VE NASIL? GÜNCEL YAKLAŞIMLAR VE LİTERATÜR DERLEMESİ. , 37 - 44. 10.36516/jocass.2021.70
Chicago	Akin Emrah,Dulger Ugur Can,Altintoprak Fatih LYNCH SENDROMUNDA PROFİLAKTİK CERRAHİ: NE ZAMAN VE NASIL? GÜNCEL YAKLAŞIMLAR VE LİTERATÜR DERLEMESİ. (2021): 37 - 44. 10.36516/jocass.2021.70
MLA	Akin Emrah,Dulger Ugur Can,Altintoprak Fatih LYNCH SENDROMUNDA PROFİLAKTİK CERRAHİ: NE ZAMAN VE NASIL? GÜNCEL YAKLAŞIMLAR VE LİTERATÜR DERLEMESİ. , 2021, ss.37 - 44. 10.36516/jocass.2021.70
AMA	Akin E,Dulger U,Altintoprak F LYNCH SENDROMUNDA PROFİLAKTİK CERRAHİ: NE ZAMAN VE NASIL? GÜNCEL YAKLAŞIMLAR VE LİTERATÜR DERLEMESİ. . 2021; 37 - 44. 10.36516/jocass.2021.70
Vancouver	Akin E,Dulger U,Altintoprak F LYNCH SENDROMUNDA PROFİLAKTİK CERRAHİ: NE ZAMAN VE NASIL? GÜNCEL YAKLAŞIMLAR VE LİTERATÜR DERLEMESİ. . 2021; 37 - 44. 10.36516/jocass.2021.70
IEEE	Akin E,Dulger U,Altintoprak F "LYNCH SENDROMUNDA PROFİLAKTİK CERRAHİ: NE ZAMAN VE NASIL? GÜNCEL YAKLAŞIMLAR VE LİTERATÜR DERLEMESİ." , ss.37 - 44, 2021. 10.36516/jocass.2021.70
ISNAD	Akin, Emrah vd. "LYNCH SENDROMUNDA PROFİLAKTİK CERRAHİ: NE ZAMAN VE NASIL? GÜNCEL YAKLAŞIMLAR VE LİTERATÜR DERLEMESİ". (2021), 37-44. https://doi.org/10.36516/jocass.2021.70

APA	Akin E, Dulger U, Altintoprak F (2021). LYNCH SENDROMUNDA PROFİLAKTİK CERRAHİ: NE ZAMAN VE NASIL? GÜNCEL YAKLAŞIMLAR VE LİTERATÜR DERLEMESİ. Çukurova Anestezi ve Cerrahi Bilimler Dergisi, 4(1), 37 - 44. 10.36516/jocass.2021.70
Chicago	Akin Emrah,Dulger Ugur Can,Altintoprak Fatih LYNCH SENDROMUNDA PROFİLAKTİK CERRAHİ: NE ZAMAN VE NASIL? GÜNCEL YAKLAŞIMLAR VE LİTERATÜR DERLEMESİ. Çukurova Anestezi ve Cerrahi Bilimler Dergisi 4, no.1 (2021): 37 - 44. 10.36516/jocass.2021.70
MLA	Akin Emrah,Dulger Ugur Can,Altintoprak Fatih LYNCH SENDROMUNDA PROFİLAKTİK CERRAHİ: NE ZAMAN VE NASIL? GÜNCEL YAKLAŞIMLAR VE LİTERATÜR DERLEMESİ. Çukurova Anestezi ve Cerrahi Bilimler Dergisi, vol.4, no.1, 2021, ss.37 - 44. 10.36516/jocass.2021.70
AMA	Akin E,Dulger U,Altintoprak F LYNCH SENDROMUNDA PROFİLAKTİK CERRAHİ: NE ZAMAN VE NASIL? GÜNCEL YAKLAŞIMLAR VE LİTERATÜR DERLEMESİ. Çukurova Anestezi ve Cerrahi Bilimler Dergisi. 2021; 4(1): 37 - 44. 10.36516/jocass.2021.70
Vancouver	Akin E,Dulger U,Altintoprak F LYNCH SENDROMUNDA PROFİLAKTİK CERRAHİ: NE ZAMAN VE NASIL? GÜNCEL YAKLAŞIMLAR VE LİTERATÜR DERLEMESİ. Çukurova Anestezi ve Cerrahi Bilimler Dergisi. 2021; 4(1): 37 - 44. 10.36516/jocass.2021.70
IEEE	Akin E,Dulger U,Altintoprak F "LYNCH SENDROMUNDA PROFİLAKTİK CERRAHİ: NE ZAMAN VE NASIL? GÜNCEL YAKLAŞIMLAR VE LİTERATÜR DERLEMESİ." Çukurova Anestezi ve Cerrahi Bilimler Dergisi, 4, ss.37 - 44, 2021. 10.36516/jocass.2021.70
ISNAD	Akin, Emrah vd. "LYNCH SENDROMUNDA PROFİLAKTİK CERRAHİ: NE ZAMAN VE NASIL? GÜNCEL YAKLAŞIMLAR VE LİTERATÜR DERLEMESİ". Çukurova Anestezi ve Cerrahi Bilimler Dergisi 4/1 (2021), 37-44. https://doi.org/10.36516/jocass.2021.70