BACKGROUND/AIMS: Nurse-nurse collaboration has an effect on job satisfaction and reducing the intention to resign by strengthening the professional image of nursing and developing a harmonious working environment in which collaboration can occur. The aim of this study was to investigate the effect of the level of collaboration between nurses on their job satisfaction. MATERIAL AND METHODS: This is a cross sectional descriptive study using the self reporting surveys of 362 nurses. The data were collected by the Minnesota Satisfaction Questionnaire (MSQ) and Nurse-Nurse Collaboration Scale (NNCS). The Kruskal-Wallis and Mann-Whitney U tests, Pearson’s product moment correlation, and regression analysis were used in the statistical analysis of the data. RESULTS: The mean NNCS and MSQ scores of the nurses were 2.78±0.44 (1–4) and 3.10±0.63 (1–5), respectively. According to the results of the statistical analysis, a significant, positive and moderate relationship was found between the overall NNCS and its subscales and the overall MSQ and its subscales (p<0.001). CONCLUSION: Nurse-nurse collaboration is one of the important factors affecting job satisfaction among nurses. Collaboration and job satisfaction of nurses are affected by various factors, including educational level, clinic at which they work, duration of professional experience, availability of people to support them in the work environment, and presence of problems experiences with other staff. Increasing the levels of collaboration will reduce the individual and organizational negative effects of job dissatisfaction.