Can first-trimester aspartate aminotransferase/platelet ratio index score predict intrahepatic cholestasis of pregnancy?

gök, koray; bostanci, mehmet suhha; Açıkgöz, Abdullah Serdar; ozden, selcuk; Takmaz, Taha; köse, osman; Tüten, Nevin

doi:10.14744/hf.2022.2022.0031

Can first-trimester aspartate aminotransferase/platelet ratio index score predict intrahepatic cholestasis of pregnancy?

Koray GÖK, (Kadın Hastalıkları ve Doğum Anabilim Dalı, Sakarya Üniversitesi Tıp Fakültesi, Sakarya, Türkiye)

Taha TAKMAZ, (Kadın Hastalıkları ve Doğum Bölümü, Bezmialem Üniversitesi Tıp Fakültesi, İstanbul, Türkiye)

Osman KÖSE, (Sakarya Eğitim ve Araştırma Hastanesi Kadın Hastalıkları ve Doğum Kliniği, Sakarya, Türkiye)

Nevin TÜTEN, (Kanuni Sultan Süleyman Eğitim ve Araştırma Hastanesi Kadın Hastalıkları ve Doğum Kliniği, İstanbul, Türkiye)

Serdar AÇIKGÖZ, (Kadın Doğum Bölümü ve Jinekoloji, İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi, İstanbul, Türkiye)

Mehmet Sühha BOSTANCI, (Kadın Hastalıkları ve Doğum Anabilim Dalı, Sakarya Üniversitesi Tıp Fakültesi, Sakarya, Türkiye)

Selçuk ÖZDEN (Kadın Hastalıkları ve Doğum Anabilim Dalı, Sakarya Üniversitesi Tıp Fakültesi, Sakarya, Türkiye)

Hepatology forum

3 0

Yıl: 2023 Cilt: 4 Sayı: 1 Sayfa Aralığı: 30 - 34 Metin Dili: İngilizce DOI: 10.14744/hf.2022.2022.0031 İndeks Tarihi: 04-06-2023

Can first-trimester aspartate aminotransferase/platelet ratio index score predict intrahepatic cholestasis of pregnancy?

Öz:

Background and Aim: The study aimed to investigate the effectiveness of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and platelet values in predicting intrahepatic cholestasis of pregnancy (ICP) in the first trimester, together with the aspartate aminotransferase/platelet ratio index (APRI) score. Materials and Methods: This study consisted of a patient group diagnosed with ICP (n=49) and a control group (n=62). Laboratory tests of both groups were analyzed retrospectively. Results: The first-trimester APRI score and AST and ALT values were found to be statistically significantly higher than those of the control group. The platelet value was found to be statistically significantly lower in the study group, even though it was within the normal reference range. Conclusion: The first-trimester APRI score was found to be effective in predicting ICP. In addition, the first-trimester AST, ALT, and platelet values were found to be effective in predicting ICP diagnosed in the third trimester even though if not as much as the APRI score.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	gök k, Takmaz T, köse o, Tüten N, Açıkgöz A, bostanci m, ozden s (2023). Can first-trimester aspartate aminotransferase/platelet ratio index score predict intrahepatic cholestasis of pregnancy?. , 30 - 34. 10.14744/hf.2022.2022.0031
Chicago	gök koray,Takmaz Taha,köse osman,Tüten Nevin,Açıkgöz Abdullah Serdar,bostanci mehmet suhha,ozden selcuk Can first-trimester aspartate aminotransferase/platelet ratio index score predict intrahepatic cholestasis of pregnancy?. (2023): 30 - 34. 10.14744/hf.2022.2022.0031
MLA	gök koray,Takmaz Taha,köse osman,Tüten Nevin,Açıkgöz Abdullah Serdar,bostanci mehmet suhha,ozden selcuk Can first-trimester aspartate aminotransferase/platelet ratio index score predict intrahepatic cholestasis of pregnancy?. , 2023, ss.30 - 34. 10.14744/hf.2022.2022.0031
AMA	gök k,Takmaz T,köse o,Tüten N,Açıkgöz A,bostanci m,ozden s Can first-trimester aspartate aminotransferase/platelet ratio index score predict intrahepatic cholestasis of pregnancy?. . 2023; 30 - 34. 10.14744/hf.2022.2022.0031
Vancouver	gök k,Takmaz T,köse o,Tüten N,Açıkgöz A,bostanci m,ozden s Can first-trimester aspartate aminotransferase/platelet ratio index score predict intrahepatic cholestasis of pregnancy?. . 2023; 30 - 34. 10.14744/hf.2022.2022.0031
IEEE	gök k,Takmaz T,köse o,Tüten N,Açıkgöz A,bostanci m,ozden s "Can first-trimester aspartate aminotransferase/platelet ratio index score predict intrahepatic cholestasis of pregnancy?." , ss.30 - 34, 2023. 10.14744/hf.2022.2022.0031
ISNAD	gök, koray vd. "Can first-trimester aspartate aminotransferase/platelet ratio index score predict intrahepatic cholestasis of pregnancy?". (2023), 30-34. https://doi.org/10.14744/hf.2022.2022.0031

APA	gök k, Takmaz T, köse o, Tüten N, Açıkgöz A, bostanci m, ozden s (2023). Can first-trimester aspartate aminotransferase/platelet ratio index score predict intrahepatic cholestasis of pregnancy?. Hepatology forum, 4(1), 30 - 34. 10.14744/hf.2022.2022.0031
Chicago	gök koray,Takmaz Taha,köse osman,Tüten Nevin,Açıkgöz Abdullah Serdar,bostanci mehmet suhha,ozden selcuk Can first-trimester aspartate aminotransferase/platelet ratio index score predict intrahepatic cholestasis of pregnancy?. Hepatology forum 4, no.1 (2023): 30 - 34. 10.14744/hf.2022.2022.0031
MLA	gök koray,Takmaz Taha,köse osman,Tüten Nevin,Açıkgöz Abdullah Serdar,bostanci mehmet suhha,ozden selcuk Can first-trimester aspartate aminotransferase/platelet ratio index score predict intrahepatic cholestasis of pregnancy?. Hepatology forum, vol.4, no.1, 2023, ss.30 - 34. 10.14744/hf.2022.2022.0031
AMA	gök k,Takmaz T,köse o,Tüten N,Açıkgöz A,bostanci m,ozden s Can first-trimester aspartate aminotransferase/platelet ratio index score predict intrahepatic cholestasis of pregnancy?. Hepatology forum. 2023; 4(1): 30 - 34. 10.14744/hf.2022.2022.0031
Vancouver	gök k,Takmaz T,köse o,Tüten N,Açıkgöz A,bostanci m,ozden s Can first-trimester aspartate aminotransferase/platelet ratio index score predict intrahepatic cholestasis of pregnancy?. Hepatology forum. 2023; 4(1): 30 - 34. 10.14744/hf.2022.2022.0031
IEEE	gök k,Takmaz T,köse o,Tüten N,Açıkgöz A,bostanci m,ozden s "Can first-trimester aspartate aminotransferase/platelet ratio index score predict intrahepatic cholestasis of pregnancy?." Hepatology forum, 4, ss.30 - 34, 2023. 10.14744/hf.2022.2022.0031
ISNAD	gök, koray vd. "Can first-trimester aspartate aminotransferase/platelet ratio index score predict intrahepatic cholestasis of pregnancy?". Hepatology forum 4/1 (2023), 30-34. https://doi.org/10.14744/hf.2022.2022.0031