TY  - JOUR
TI  - Can first-trimester aspartate aminotransferase/platelet ratio index score predict intrahepatic cholestasis of pregnancy?
AB  - Background and Aim: The study aimed to investigate the effectiveness of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and platelet values in predicting intrahepatic cholestasis of pregnancy (ICP) in the first trimester, together with the aspartate aminotransferase/platelet ratio index (APRI) score. Materials and Methods: This study consisted of a patient group diagnosed with ICP (n=49) and a control group (n=62). Laboratory tests of both groups were analyzed retrospectively. Results: The first-trimester APRI score and AST and ALT values were found to be statistically significantly higher than those of the control group. The platelet value was found to be statistically significantly lower in the study group, even though it was within the normal reference range. Conclusion: The first-trimester APRI score was found to be effective in predicting ICP. In addition, the first-trimester AST, ALT, and platelet values were found to be effective in predicting ICP diagnosed in the third trimester even though if not as much as the APRI score.
AU  - gök, koray
AU  - bostanci, mehmet suhha
AU  - Açıkgöz, Abdullah Serdar
AU  - ozden, selcuk
AU  - Takmaz, Taha
AU  - köse, osman
AU  - Tüten, Nevin
DO  - 10.14744/hf.2022.2022.0031
PY  - 2023
JO  - Hepatology forum
VL  - 4
IS  - 1
SN  - 1307-5888
SP  - 30
EP  - 34
DB  - TRDizin
UR  - http://search/yayin/detay/1179043
ER  -