Yıl: 2023 Cilt: 26 Sayı: 2 Sayfa Aralığı: 132 - 142 Metin Dili: İngilizce DOI: 10.5505/kpd.2023.93764 İndeks Tarihi: 05-07-2023

How do traumatic experiences affect relapse in alcohol and substance use disorders?

Öz:
Objective: Relapses are very common in Alcohol and Substance Use Disorders (ASUD). Although traumatic experiences are more common in patients with ASUD than in the normal population, its relationship with relapses has not been adequately studied. Method: Fifty-one patients who were hospitalized diagnosed with ASUD according to DSM 5 were included in the study. Sociodemographic Data Form, Impact of Events Scale-R (IES-R), Hamilton Depression Rating Scale (HAM-D), Hamilton Anxiety Rating Scale (HAM-A), Dissociative Experiences Scale (DES), Addiction Profile Index (API), The Stages of Change Readiness and Treatment Eagerness Scale (SOCRATES) and Traumatic Experiences Checklist (TEC) were applied during their hospitalization. Patients were evaluated for relapse in the 6th month after discharge. Results: Relapse was observed in 60.8% of the participants. A statistically significant difference was found between the groups with and without relapse in terms of previous psychiatric treatment, number of traumatic events and severity, neglect, emotional and physical abuse, HAM-A and DES scores (p˂0.05). In the logistic regression analysis, it was found that not having previously applied for psychiatric treatment significantly predicted early relapses. Discussion: According to the study results, the previous psychiatric treatment seems to be associated with lower relapse rates. In contrast, traumatic experiences, anxiety, and dissociative symp- toms seem to be associated with higher relapse rates.
Anahtar Kelime:

Alkol ve madde kullanım bozukluklarında travmatik yaşantılar nüksleri nasıl etkiliyor?

Öz:
Amaç: Alkol ve Madde Kullanım Bozukluklarında (AMKB) nüksler çok yaygındır. AMKB hastalarında travmatik deneyimler normal popülasyona göre daha yaygın olmasına rağmen, relapslarla ilişkisi yeterince çalışılmamıştır. Yöntem: Çalışmaya DSM 5'e göre AMKB tanısı ile yatırılan 51 hasta dahil edildi. Sosyodemografik Veri Formu, Olayların Etkisi Ölçeği-R (OEÖ-R), Hamilton Depresyon Derecelendirme Ölçeği (HAM-D), Hamilton Anksiyete Derecelendirme Ölçeği (HAM-A), Disosiyatif Yaşantılar Ölçeği (DES), Bağımlılık Profil İndeksi (BAPI), Hastaneye yatışları sırasında Değişime Hazırlık Aşamaları ve Tedaviye İsteklilik Ölçeği (SOCRATES) ve Travmatik Deneyimler Kontrol Listesi (TDKL) uygulandı. Hastalar taburculuk sonrası 6. ayda nüksler açısından değerlendirildi. Bulgular: Katılımcıların %60, 8’inde nüks görüldü. Nüks olan ve olmayan gruplar arasında önceki psikiyatrik tedavi, travmatik olay sayısı ve şiddeti, ihmal, duygusal ve fiziksel istismar, HAM-A ve DES puanları açısından istatistiksel olarak anlamlı fark bulundu. (p˂0.05). Lojistik regresyon analizinde daha önce psiki- yatrik tedaviye başvurmamış olmanın erken dönem yinelemeleri anlamlı olarak yordadığı bulundu. Sonuç: Çalışma sonuçlara göre daha önce psikiyatrik tedaviye başvurmuş olmak daha düşük nüks oranları ile ilişkili görünmektedir. Buna karşılık travmatik deneyimler, anksiyete ve dissosiyatif semptomlar yüksek nüks oranları ile ilişkili gibi görünmektedir.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. Farley M, Golding JM, Young G, Mulligan M, Minkoff JR. Trauma history and relapse probability among patients seeking substance abuse treatment. J Subst Use Addict Treat. 2004;27(2):161-7.
  • 2. Avrupa Uyuşturucu ve Uyuşturucu Bağımlılığını İzleme Merkezi (2018), Avrupa Uyuşturucu Raporu, 2018: Eğilimler ve Gelişmeler. Lüksemburg: 2018.
  • 3. Greenfield SF, Kolodziej ME, Sugarman DE, Muenz LR, Vagge LM, He DY, Weiss RD. History of abuse and drinking outcomes following inpatient alcohol treatment: A prospective study. Drug Alcohol Depend. 2002;67(3):227-34.
  • 4. Brady KT, Back SE, Coffey SF. Substance abuse and posttrau- matic stress disorder. Curr Dir Psychol Sci. 2004;13(5):206-9.
  • 5. Hyman SM, Paliwal P, Chaplin TM, Mazure CM, Rounsaville BJ, Sinha R. Severity of childhood trauma is predictive of cocaine relapse outcomes in women but not men. Drug Alcohol Depend. 2008;92(1-3):208-16.
  • 6. Ouimette PC, Finney JW, Moos RH. Two-year posttreatment functioning and coping of substance abuse patients with post- traumatic stress disorder. Psychol Addict Behav. 1999;13(2):105.
  • 7. Brown PJ, Stout RL, Mueller T. Posttraumatic stress disorder and substance abuse relapse among women: A pilot study. Psychol Addict Behav 1996;10(2):124.
  • 8. Umut G, Evren C, Unal GT. Could childhood trauma types predict the relapse in alcohol use disorder? Asian J Psychiatr 2017;100(25):253.
  • 9. Sadock BJ, Sadock VA, Ruiz P. Kaplan Sadock Synopsis of Psychiatry Davranış Bilimleri/Klinik Psikiyatri. 11 ed. Kuloğlu M, Geçici Ö, editors: Güneş tıp kitabevi 2016.
  • 10. Horowitz M, Wilner N, Alvarez W. Impact of Event Scale: A measure of subjective stress. Psychosomatic medicine. 1979;41(3):209-18.
  • 11. Weiss DS, Marmar CR. The Impact of Event Scale— Revised. Assessing psychological trauma and PTSD. New York, NY, US: The Guilford Press; 1997. p. 399-411.
  • 12. Çorapçıoğlu A, Yargıç İ, Geyran P, Kocabaşoğlu N. Validity and Reliability of Turkish Version of "Impact of Event Scale- Revised" (IES-R). New/Yeni Symposium Journal 2006;44(1):14- 22.
  • 13. Hamilton M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960;23(1):56.
  • 14. Akdemir A, Örsel S, Dağ İ, Türkçapar H, İşcan N, Özbay H. Hamilton Depresyon Derecelendirme Ölçeği (HDDÖ)’nin geçerliği, güvenirliği ve klinikte kullanımı. 3 P Psikiyatri Psikoloji Psikofarmakoloji Dergisi. 1996;4(4):251-9.
  • 15. Hamilton M. The assessment of anxiety states by rating. Br J Med Psychol. 1959;32(1):50-5.
  • 16. Yazıcı MK, Demir B, Tanrıverdi N, Karaağaoğlu E, Yolaç P. Hamilton Anksiyete Değerlendirme Ölçeği, değerlendiriciler arası güvenirlik ve geçerlik çalışması. Turk Psikiyatri Derg 1998;9(2):114-7.
  • 17. Bernstein EM, Putnam FW. Development, reliability, and validity of a dissociation scale. J Nerv Ment Dis. 1986;Dec;174(12):727-35.
  • 18. Carlson EB, Putnam FW. An update on the dissociative experiences scale. Dissociation: progress in the dissociative dis- orders. 1993;6(1):16-20.
  • 19. Yargic LI, Tutkun H, Sar V. Reliability and validity of the Turkish version of the Dissociative Experiences Scale. Dissociation: Progress in the Dissociative Disorders. 1995;8(1):10-3.
  • 20. Ögel K, Evren C, Karadağ F, Gürol T. Bağımlılık Profil İndeksi’nin (BAPİ) geliştirilmesi, geçerlik ve güvenilirliği. Turk Psikiyatri Derg 2012;23(4):264-73.
  • 21. Miller WR, Tonigan JS. Assessing drinkers' motivation for change: The Stages of Change Readiness and Treatment Eagerness Scale (SOCRATES). Washington, DC, US: American Psychological Association; 1997. 355-69 p.
  • 22. Evren C, Gürol DT, Ögel K. Reliability and validity of Turkish Version the Stages of Change Readiness and Treatment Eagerness Scale (SOCRATES) in male substance dependent inpatients. Turk Psikiyatri Dergisi. 2011;22(Suppl 1):70-1.
  • 23. Nijenhuis ER, Van der Hart O, Kruger K. The psychometric characteristics of the Traumatic Experiences Checklist (TEC): First findings among psychiatric outpatients. Clinical Psychology Psychotherapy: An International Journal of Theory Practice. 2002;9(3):200-10.
  • 24. Şar V. Travmatik Yaşantılar Ölçeği (TEQ) 2002. Available from: https://www.vedatsar.com/psikiyatrik-olcekler/.
  • 25. Overall JE, Gorham DR. The brief psychiatric rating scale. Psychological reports. 1962;10(3):799-812.
  • 26. Aydemir Ö, Köroğlu E. Psikiyatride Kullanılan Klinik Ölçekler. 3’üncü baskı. Ankara Hekimler Yayın Birliği. 2007;346:353.
  • 27. Yazici AB, Yazici E, Kumsar NA, Erol A. Addiction profile in probation practices in Turkey: 5-year data analysis. Neuropsychiatr Dis Treat 2015;11:2259.
  • 28. Tanyeri P, Yazici AB, Buyukokuroglu ME, Yazici E, Erol A. Urinary extract profiles of illegal substances at psychiatry and dependency clinics: three years report. International Journal of Basic & Clinical Pharmacology. 2017;6(3):495.
  • 29. Ögel K. Alkol ve madde kullanım bozukluklarında damgala- ma. 3 P Psikiyatri Psikoloji Psikofarmakoloji Dergisi. 2004;12:25.
  • 30. Evren C, Evren B, Ögel K, Çakmak D. Madde kullanımı nedeni ile yatarak tedavi görenlerde intihar girişimi öyküsü. Klinik Psikiyatri Dergisi. 2001;4(4):232-40.
  • 31. Evren C, Karabulut V, Can Y, Bozkurt M, Umut G, Evren B. Predictors of outcome during a 6-month follow-up among hero- in dependent patients receiving buprenorphine/naloxone main- tenance treatment. Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology. 2014;24(4):311-22.
  • 32. Roy A. Characteristics of drug addicts who attempt suicide. Psychiatry research. 2003;121(1):99-103.
  • 33. Roglio VS, Borges EN, Rabelo-da-Ponte FD, Ornell F, Scherer JN, Schuch JB, Passos IC, Sanvicente-Vieira B, Grassi- Oliveira R, von Diemen L, Pechansky F, Kessler FHP. Prediction of attempted suicide in men and women with crack-cocaine use disorder in Brazil. PloS one. 2020;15(5):e0232242. PubMed PMID: 32365094. Pubmed Central PMCID: PMC7197800. Epub 2020/05/05. eng.
  • 34. Yuodelis-Flores C, Ries RK. Addiction and suicide: A review. Am J Addict 2015 Mar;24(2):98-104. PubMed PMID:25644860. Epub 2015/02/04. eng.
  • 35. Doğruer Z, Türkçapar MH, İnce A. Alkol bağımlılığında relaps. Klinik Psikiyatri. 2002;5:43-9.
  • 36. Saatçioğlu Ö, Yapıcı A, Ciğerli G, Üney R, Çakmak D. Yatarak tedavi gören bağımlı hastalarda nüksün değerlendirilmesi. Bağımlılık Dergisi. 2007;8(3):133-7.
  • 37. Connors GJ, Maisto SA, Zywiak WH. Understanding relapse in the broader context of post treatment functioning. Addiction. 1996;91(12s1):173-90.
  • 38. Maisto SA, Pollock NK, Cornelius JR, Lynch KG, Martin CS. Alcohol relapse as a function of relapse definition in a clin- ical sample of adolescents. Addict Behav 2003;28(3):449-59.
  • 39. Evren C, Durkaya M, Evren B, Dalbudak E, Cetin R. Relationship of relapse with impulsivity, novelty seeking and craving in male alcohol dependent inpatients. Drug Alcohol Rev. 2012;31(1):81-90.
  • 40. National Institute on Drug Abuse (2019) The Science of Drug Use and Addiction: The Basics. Available at: https://www.drugabuse.gov/publications/media-guide/science- drug-use-addiction-basics.
  • 41. ŞAmar B, Buz S. Bağımlılık Rehabilitasyonunda Sosyal Hizmet Uygulamaları: Erenköy BAHAR Modeli. Bağımlılık Dergisi. 2022;23(2):221-32.
  • 42. Wojnar M, Ilgen MA, Jakubczyk A, Wnorowska A, Klimkiewicz A, Brower KJ. Impulsive suicide attempts predict post-treatment relapse in alcohol-dependent patients. Drug Alcohol Depend 2008;97(3):268-75.
  • 43. Bradizza C, Stasiewicz P, Paas N. Relapse to alcohol and drug use among individuals diagnosed with co-occurring mental health and substance use disorders: A review. Clin Psychol Rev. 2006 04/01;26:162-78.
  • 44. Khantzian EJ. The self-medication hypothesis of addictive disorders: focus on heroin and cocaine dependence. The cocaine crisis: Springer; 1987. p. 65-74.
  • 45. Tırışkana M, Onnarb N, Çetinc YA, Cömertd IT. The Importance of Mindfulness in Preventing Substance-Abuse Relapse: A Literature Review. Addicta: The Turkish Journal on Addictions. 2015;2(2):123-42.
  • 46. Bradizza CM, Stasiewicz PR, Paas ND. Relapse to alcohol and drug use among individuals diagnosed with co-occurring mental health and substance use disorders: a review. Clin Psychol Rev 2006;26(2):162-78.
  • 47. Bilici R, Yazici E, Tufan AE, Mutlu E, İzci F, Uğurlu GK. Motivation for treatment in patients with substance use disor- der: personal volunteering versus legal/familial enforcement. Neuropsychiatr Dis Treat 2014;10:1599.
  • 48. Claus RE, Kindleberger LR. Engaging substance abusers after centralized assessment: Predictors of treatment entry and dropout. J Psychoactive Drugs 2002;34(1):25-31.
  • 49. Nosyk B, Geller J, Guh DP, Oviedo-Joekes E, Brissette S, Marsh DC, Schechter MT, Anis AH. The effect of motivational status on treatment outcome in the North American Opiate Medication Initiative (NAOMI) study. Drug Alcohol Depend 2010;111(1-2):161-5.
  • 50. Gerra G, Borella F, Zaimovic A, Moi G, Bussandri M, Bubici C, Bertacca S. Buprenorphine versus methadone for opioid dependence: predictor variables for treatment outcome. Drug Alcohol Depend. 2004;75(1):37-45.
  • 51. Heinz AJ, Epstein DH, Schroeder JR, Singleton EG, Heishman SJ, Preston KL. Heroin and cocaine craving and use during treatment: measurement validation and potential rela- tionships. J Subst Abuse Treat 2006;31(4):355-64.
  • 52. Serin RC, Kennedy S. Treatment readiness and responsivity: Contributing to effective correctional programming: Correctional Service Canada, Corporate Development, Research Branch; 1997.
  • 53. Somer E. Opioid use disorder and dissociation. Dissociation and the dissociative disorders: DSM-V and beyond. New York, NY, US: Routledge/Taylor & Francis Group; 2009. p. 511-8.
  • 54. Driessen M, Meier S, Hill A, Wetterling T, Lange W, Junghanns K. The course of anxiety, depression and drinking behaviours after completed detoxification in alcoholics with and without comorbid anxiety and depressive disorders. Alcohol Alcohol 2001;36(3):249-55.
  • 55. Cerdá M, Tracy M, Galea S. A prospective population based study of changes in alcohol use and binge drinking after a mass traumatic event. Drug Alcohol Depend 2011;115(1-2):1-8.
  • 56. Westermeyer J, Wahmanholm K, Thuras P. Effects of child- hood physical abuse on course and severity of substance abuse. Am J Addict 2001;10(2):101-10.
  • 57. Hien DA, Nunes E, Levin FR, Fraser D. Posttraumatic stress disorder and short-term outcome in early methadone treatment. J Subst Abuse Treat 2000;19(1):31-7.
  • 58. Hines DA, Armstrong JL, Reed KP, Cameron AY. Gender differences in sexual assault victimization among college stu- dents. Violence Vict 2012;27(6):922-40. PubMed PMID: 23393954. Epub 2013/02/12. eng.
  • 59. Hasin D, Liu X, Nunes E, McCloud S, Samet S, Endicott J. Effects of major depression on remission and relapse of sub- stance dependence. Arch Gen Psychiatry 2002;59(4):375-80.
  • 60. Noone M, Dua J, Markham R. Stress, cognitive factors, and coping resources as predictors of relapse in alcoholics. Addict Behav 1999;24(5):687-93.
  • 61. Kushner MG, Sher KJ, Beitman BD. The relation between alcohol problems and the anxiety disorders. Am J Psychiatry 1990;Jun;147(6):685-95.
  • 62. Evren C, Sar V, Dalbudak E, Cetin R, Durkaya M, Evren B, Celik S. Lifetime PTSD and quality of life among alcohol- dependent men: impact of childhood emotional abuse and dis- sociation. Psychiatry Res 2011;186(1):85-90.
  • 63. Prochaska JO, Di Clemente CC. Stages and processes of self-change of smoking: toward an integrative model of change. J Consult Clin Psychol 1983 Jun;51(3):390-5. PubMed PMID: 6863699. Epub 1983/06/01. eng.
  • 64. Ür S. Alkol bağımlılığı tedavisinde nüks ve nüksü belirleyen etkenler İstanbul1997.
  • 65. Park-Lee E, Lipari RN, Hedden SL, Kroutil LA, Porter JD. Receipt of services for substance use and mental health issues among adults: results from the 2016 National Survey on Drug Use and Health. CBHSQ Data Review: Substance Abuse and Mental Health Services Administration (US); 2017.
APA Türker Mercandağı E, Yazici A, Yazici E (2023). How do traumatic experiences affect relapse in alcohol and substance use disorders?. , 132 - 142. 10.5505/kpd.2023.93764
Chicago Türker Mercandağı Ebru,Yazici Ahmet Bulent,Yazici Esra How do traumatic experiences affect relapse in alcohol and substance use disorders?. (2023): 132 - 142. 10.5505/kpd.2023.93764
MLA Türker Mercandağı Ebru,Yazici Ahmet Bulent,Yazici Esra How do traumatic experiences affect relapse in alcohol and substance use disorders?. , 2023, ss.132 - 142. 10.5505/kpd.2023.93764
AMA Türker Mercandağı E,Yazici A,Yazici E How do traumatic experiences affect relapse in alcohol and substance use disorders?. . 2023; 132 - 142. 10.5505/kpd.2023.93764
Vancouver Türker Mercandağı E,Yazici A,Yazici E How do traumatic experiences affect relapse in alcohol and substance use disorders?. . 2023; 132 - 142. 10.5505/kpd.2023.93764
IEEE Türker Mercandağı E,Yazici A,Yazici E "How do traumatic experiences affect relapse in alcohol and substance use disorders?." , ss.132 - 142, 2023. 10.5505/kpd.2023.93764
ISNAD Türker Mercandağı, Ebru vd. "How do traumatic experiences affect relapse in alcohol and substance use disorders?". (2023), 132-142. https://doi.org/10.5505/kpd.2023.93764
APA Türker Mercandağı E, Yazici A, Yazici E (2023). How do traumatic experiences affect relapse in alcohol and substance use disorders?. Klinik Psikiyatri Dergisi, 26(2), 132 - 142. 10.5505/kpd.2023.93764
Chicago Türker Mercandağı Ebru,Yazici Ahmet Bulent,Yazici Esra How do traumatic experiences affect relapse in alcohol and substance use disorders?. Klinik Psikiyatri Dergisi 26, no.2 (2023): 132 - 142. 10.5505/kpd.2023.93764
MLA Türker Mercandağı Ebru,Yazici Ahmet Bulent,Yazici Esra How do traumatic experiences affect relapse in alcohol and substance use disorders?. Klinik Psikiyatri Dergisi, vol.26, no.2, 2023, ss.132 - 142. 10.5505/kpd.2023.93764
AMA Türker Mercandağı E,Yazici A,Yazici E How do traumatic experiences affect relapse in alcohol and substance use disorders?. Klinik Psikiyatri Dergisi. 2023; 26(2): 132 - 142. 10.5505/kpd.2023.93764
Vancouver Türker Mercandağı E,Yazici A,Yazici E How do traumatic experiences affect relapse in alcohol and substance use disorders?. Klinik Psikiyatri Dergisi. 2023; 26(2): 132 - 142. 10.5505/kpd.2023.93764
IEEE Türker Mercandağı E,Yazici A,Yazici E "How do traumatic experiences affect relapse in alcohol and substance use disorders?." Klinik Psikiyatri Dergisi, 26, ss.132 - 142, 2023. 10.5505/kpd.2023.93764
ISNAD Türker Mercandağı, Ebru vd. "How do traumatic experiences affect relapse in alcohol and substance use disorders?". Klinik Psikiyatri Dergisi 26/2 (2023), 132-142. https://doi.org/10.5505/kpd.2023.93764