Mean Platelet Volume in Patients with Subclavian Artery Stenosis

Objective Thrombocytes and mean platelet volume (MPV) are related to atherosclerosis. The purpose of the present study was to investigate the relationship between MPV and subclavian artery stenosis (SAS). Materials and Methods Patients who were diagnosed with SAS by an angiography performed in the catheter laboratory between September 2010 and September 2015 were included in this study. A control group with similar clinical and demographic characteristics as the patients with SAS in angiographic terms was formed. The MPV and other hemogram values for SAS patients (35 patients) and the patients in the control group (38 patients) were determined retrospectively from the registry system and then compared. Results The two groups were similar to each other in terms of demographic and clinical characteristics. When the hemogram parameters were compared between the groups, the MPV was detected as being significantly higher in patients with SAS (8.07 ± 1.41 vs 7.19 ± 0.52; p = 0.001). Conclusion In conclusion, this study was the first to find a higher MPV in patients with SAS. Considering both the effect of platelets on atherosclerosis and their close association with other risk factors, MPV level may be an important factor in pathogenesis of SAS.

Anahtar Kelime:

Subklavyen Arter Stenozu Olan Hastalarda Ortalama Trombosit Hacmi

Öz:

Amaç Trombositler ve ortalama trombosit hacmi ateroskleroz ile ilişkilidir. Bu çalışmanın amacı, ortalama trombosit hacmi ile subklavyen arter darlığı arasındaki ilişkiyi araştırmaktır. Gereç ve Yöntemler Sakarya Üniversitesi Eğitim ve Araştırma Hastanesi kateter laboratuvarında Eylül 2010 - Eylül 2015 tarihleri arasında yapılan anjiyografi ile subklavyen arter darlığı tanısı alan hastalar retrospektif olarak çalışmaya dahil edildi. Subklavyen arter darlığı olan hastalar ile anjiyografik açıdan benzer klinik ve demografik özelliklere sahip bir kontrol grubu oluşturuldu. Subklavyen arter darlığı olan hastalar (35 hasta) ve kontrol grubundaki hastalar (38 hasta) için ortalama trombosit hacmi ve diğer hemogram değerleri kayıt sisteminden geriye dönük olarak belirlenmiş ve karşılaştırılmıştır. Bulgular İki grup yaş, cinsiyet, ateroskleroz risk faktörleri, koroner arter hastalığı öyküsü ve ilaç kullanımı açısından birbirine benzerdi. Gruplar arasında hemogram parametreleri karşılaştırıldığında, ortalama trombosit hacmi subklavyen arteriyel darlığı olan hastalarda kontrol grubuna göre anlamlı olarak yüksek saptandı (8,07 ± 1,41 vs 7,19 ± 0,52; p = 0,001). Sonuç Sonuç olarak, bu çalışma subklavyen arter darlığı olan hastalarda daha yüksek ortalama trombosit hacmi bulan ilk çalışma olmuştur. Hem trombositlerin ateroskleroz üzerindeki etkisi hem de diğer risk faktörleri ile yakın ilişkisi düşünüldüğünde MPV düzeyi subklavyen arter darlığının patogenezinde önemli bir factor olabilir.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	can y, şahinkuş s, kocayigit i, Aksoy M, ösken a, Gunduz H, Aydın E, YAYLACI S, Kilic H, Akdemir R (2021). Mean Platelet Volume in Patients with Subclavian Artery Stenosis. , 259 - 264. 10.31832/smj.858568
Chicago	can yusuf,şahinkuş salih,kocayigit ibrahim,Aksoy Muhammed Necati Murat,ösken altuğ,Gunduz Huseyin,Aydın Ercan,YAYLACI SELÇUK,Kilic Harun,Akdemir Ramazan Mean Platelet Volume in Patients with Subclavian Artery Stenosis. (2021): 259 - 264. 10.31832/smj.858568
MLA	can yusuf,şahinkuş salih,kocayigit ibrahim,Aksoy Muhammed Necati Murat,ösken altuğ,Gunduz Huseyin,Aydın Ercan,YAYLACI SELÇUK,Kilic Harun,Akdemir Ramazan Mean Platelet Volume in Patients with Subclavian Artery Stenosis. , 2021, ss.259 - 264. 10.31832/smj.858568
AMA	can y,şahinkuş s,kocayigit i,Aksoy M,ösken a,Gunduz H,Aydın E,YAYLACI S,Kilic H,Akdemir R Mean Platelet Volume in Patients with Subclavian Artery Stenosis. . 2021; 259 - 264. 10.31832/smj.858568
Vancouver	can y,şahinkuş s,kocayigit i,Aksoy M,ösken a,Gunduz H,Aydın E,YAYLACI S,Kilic H,Akdemir R Mean Platelet Volume in Patients with Subclavian Artery Stenosis. . 2021; 259 - 264. 10.31832/smj.858568
IEEE	can y,şahinkuş s,kocayigit i,Aksoy M,ösken a,Gunduz H,Aydın E,YAYLACI S,Kilic H,Akdemir R "Mean Platelet Volume in Patients with Subclavian Artery Stenosis." , ss.259 - 264, 2021. 10.31832/smj.858568
ISNAD	can, yusuf vd. "Mean Platelet Volume in Patients with Subclavian Artery Stenosis". (2021), 259-264. https://doi.org/10.31832/smj.858568

APA	can y, şahinkuş s, kocayigit i, Aksoy M, ösken a, Gunduz H, Aydın E, YAYLACI S, Kilic H, Akdemir R (2021). Mean Platelet Volume in Patients with Subclavian Artery Stenosis. Sakarya Tıp Dergisi, 11(2), 259 - 264. 10.31832/smj.858568
Chicago	can yusuf,şahinkuş salih,kocayigit ibrahim,Aksoy Muhammed Necati Murat,ösken altuğ,Gunduz Huseyin,Aydın Ercan,YAYLACI SELÇUK,Kilic Harun,Akdemir Ramazan Mean Platelet Volume in Patients with Subclavian Artery Stenosis. Sakarya Tıp Dergisi 11, no.2 (2021): 259 - 264. 10.31832/smj.858568
MLA	can yusuf,şahinkuş salih,kocayigit ibrahim,Aksoy Muhammed Necati Murat,ösken altuğ,Gunduz Huseyin,Aydın Ercan,YAYLACI SELÇUK,Kilic Harun,Akdemir Ramazan Mean Platelet Volume in Patients with Subclavian Artery Stenosis. Sakarya Tıp Dergisi, vol.11, no.2, 2021, ss.259 - 264. 10.31832/smj.858568
AMA	can y,şahinkuş s,kocayigit i,Aksoy M,ösken a,Gunduz H,Aydın E,YAYLACI S,Kilic H,Akdemir R Mean Platelet Volume in Patients with Subclavian Artery Stenosis. Sakarya Tıp Dergisi. 2021; 11(2): 259 - 264. 10.31832/smj.858568
Vancouver	can y,şahinkuş s,kocayigit i,Aksoy M,ösken a,Gunduz H,Aydın E,YAYLACI S,Kilic H,Akdemir R Mean Platelet Volume in Patients with Subclavian Artery Stenosis. Sakarya Tıp Dergisi. 2021; 11(2): 259 - 264. 10.31832/smj.858568
IEEE	can y,şahinkuş s,kocayigit i,Aksoy M,ösken a,Gunduz H,Aydın E,YAYLACI S,Kilic H,Akdemir R "Mean Platelet Volume in Patients with Subclavian Artery Stenosis." Sakarya Tıp Dergisi, 11, ss.259 - 264, 2021. 10.31832/smj.858568
ISNAD	can, yusuf vd. "Mean Platelet Volume in Patients with Subclavian Artery Stenosis". Sakarya Tıp Dergisi 11/2 (2021), 259-264. https://doi.org/10.31832/smj.858568