TY  - JOUR
TI  - Multidrug resistance in pathogens of community-acquired urinary tract infections in Turkey: a multicentre prospective observational study
AB  - Background/aim: To have country-wide information about multidrug resistance (MDR) in isolates from community-acquired urinary tract infections (CAUTI) of Turkey, in terms of resistance rates and useful options. Materials and methods: We used a geocode standard, nomenclature of territorial units for statistics (NUTS), and a total of 1588 community-acquired isolates of 20 centres from 12 different NUTS regions between March 2019 and March 2020 were analysed. Results: Of the 1588 culture growths, 1269 (79. 9%) were Escherichia coli and 152 (9.6%) were Klebsiella spp. Male sex, advanced age, and having two or more risk factors showed a statistically significant relation with MDR existence (p < 0.001, p: 0.014, p < 0.001, respectively) that increasing number of risk factors or degree of advancing in age directly affects the number of antibiotic groups detected to have resistance by pathogens. In total, MDR isolates corresponded to 36.1% of our CAUTI samples; MDR existence was 35.7% in E. coli isolates and 57.2% in Klebsiella spp. isolates. Our results did not show an association between resistance or MDR occurrence rates and NUTS regions. Conclusion: The necessity of urine culture in outpatient clinics should be taken into consideration, at least after evaluating risk factors for antibacterial resistance individually. Community-acquired UTIs should be followed up time- and region-dependently. Antibiotic stewardship programmes should be more widely and effectively administrated.
AU  - Sencan, İrfan
AU  - KARABAY, OĞUZ
AU  - altay, fatma aybala
AU  - Suzuk Yıldız, Serap
AU  - Şimşek, Hüsniye
AU  - Gözükara, Melih Gaffar
AU  - Kuzi, Semanur
AU  - ESER KARLIDAG, Gulden
AU  - Kaya, Safak
AU  - kul, gülnur
AU  - Türkoğlu Yılmaz, Emine
AU  - Korkmaz, Nesibe
AU  - Yıldız Kaya, Sibel
AU  - SAYAR, MERVE SEFA
AU  - Bulut, Dilek
AU  - akgul, fethiye
AU  - Cag, Yasemin
AU  - Agalar, Canan
AU  - Bestepe Dursun, Zehra
AU  - Tasbakan, meltem
AU  - Erdem, Huseyin Aytac
AU  - Aydemir, Sohret
AU  - Seyman, Derya
AU  - YILDIRIM, Mustafa
AU  - habip, zafer
AU  - altın, nilgün
AU  - Uzar, Hanife
AU  - Bektaş, Begüm
AU  - Öztürk Engin, Derya
AU  - Sürme, Serkan
AU  - ergut sezer, busra
DO  - 10.55730/1300-0144.5641
PY  - 2023
JO  - Turkish Journal of Medical Sciences
VL  - 53
IS  - 3
SN  - 1300-0144
SP  - 780
EP  - 790
DB  - TRDizin
UR  - http://search/yayin/detay/1191056
ER  -