A Case of Hepatitis B Reactivation with Acute Flare Three Months After Tenofovir Prophylaxis Withdrawal in a Allogenic Hematopoietic Stem Cell Transplantation Patient
Yıl: 2018 Cilt: 24 Sayı: 2 Sayfa Aralığı: 61 - 64 Metin Dili: İngilizce DOI: 10.4274/vhd.2018.0001 İndeks Tarihi: 05-02-2019
A Case of Hepatitis B Reactivation with Acute Flare Three Months After Tenofovir Prophylaxis Withdrawal in a Allogenic Hematopoietic Stem Cell Transplantation Patient
Öz: Hepatitis B virus (HBV) infection is a major health problemworldwide. HBV reactivation is associated with high mortality ratesin hematopoietic stem cell transplantation (HSCT) and, prophylacticantiviral treatment is suggested to prevent this phenomenon.However, the duration of antiviral treatment in HSCT patients isnot fully defined and the time of immune recovery is consideredthe best parameter for a drug to be safely interrupted. We aimedto present a case of hepatitis B reactivation after cessation ofone-year prophylactic tenofovir treatment in a anti-hepatitis B coreimmunoglobulin G-positive patient who received allogenic HSCTtreatment for chronic lymphocytic leukemia.
Anahtar Kelime: Konular:
Bir Allojenik Hematopoietik Kök Hücre Nakli Hastasında, Tenofovir Profilaksisinin Bırakılmasından Üç Ay Sonra Akut Alevlenme ile Hepatit B Reaktivasyon Olgusu
Öz: Hepatit B virüs (HBV) enfeksiyonu dünya çapında önemli bir sağlık sorunudur. Hematopoietik kök hücre transplantasyonunda (HSCT) HBV reaktivasyonu yüksek mortalite oranları ile ilişkilidir ve bu durumun önlenmesi için profilaktik antiviral tedavi önerilmektedir. Bununla birlikte, HSCT hastalarında verilecek antiviral tedavinin süresi tam olarak tanımlanmamıştır ve antiviral tedavinin sonlandırılmasında bağışıklık kazanım zamanı en güvenilir parametre olarak kabul edilmektedir. Biz burada, kronik lenfositik lösemi tanısıyla allojenik HSCT tedavisi uygulanan anti-hepatit B core immünoglobulin G pozitif bir hastada transplant sonrası verilen bir yıl profilaktik tenofovir tedavisinin kesilmesi sonrasında ortaya çıkan bir hepatit B reaktivasyonu olgusunu sunmayı amaçladık.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Erişime Açık
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| APA | toka b, EMİNLER A, ASLAN F, KÖKSAL A, Altindis M (2018). A Case of Hepatitis B Reactivation with Acute Flare Three Months After Tenofovir Prophylaxis Withdrawal in a Allogenic Hematopoietic Stem Cell Transplantation Patient. , 61 - 64. 10.4274/vhd.2018.0001 |
| Chicago | toka bilal,EMİNLER Ahmet Tarık,ASLAN Ferhat Gürkan,KÖKSAL Aydın Şeref,Altindis Mustafa A Case of Hepatitis B Reactivation with Acute Flare Three Months After Tenofovir Prophylaxis Withdrawal in a Allogenic Hematopoietic Stem Cell Transplantation Patient. (2018): 61 - 64. 10.4274/vhd.2018.0001 |
| MLA | toka bilal,EMİNLER Ahmet Tarık,ASLAN Ferhat Gürkan,KÖKSAL Aydın Şeref,Altindis Mustafa A Case of Hepatitis B Reactivation with Acute Flare Three Months After Tenofovir Prophylaxis Withdrawal in a Allogenic Hematopoietic Stem Cell Transplantation Patient. , 2018, ss.61 - 64. 10.4274/vhd.2018.0001 |
| AMA | toka b,EMİNLER A,ASLAN F,KÖKSAL A,Altindis M A Case of Hepatitis B Reactivation with Acute Flare Three Months After Tenofovir Prophylaxis Withdrawal in a Allogenic Hematopoietic Stem Cell Transplantation Patient. . 2018; 61 - 64. 10.4274/vhd.2018.0001 |
| Vancouver | toka b,EMİNLER A,ASLAN F,KÖKSAL A,Altindis M A Case of Hepatitis B Reactivation with Acute Flare Three Months After Tenofovir Prophylaxis Withdrawal in a Allogenic Hematopoietic Stem Cell Transplantation Patient. . 2018; 61 - 64. 10.4274/vhd.2018.0001 |
| IEEE | toka b,EMİNLER A,ASLAN F,KÖKSAL A,Altindis M "A Case of Hepatitis B Reactivation with Acute Flare Three Months After Tenofovir Prophylaxis Withdrawal in a Allogenic Hematopoietic Stem Cell Transplantation Patient." , ss.61 - 64, 2018. 10.4274/vhd.2018.0001 |
| ISNAD | toka, bilal vd. "A Case of Hepatitis B Reactivation with Acute Flare Three Months After Tenofovir Prophylaxis Withdrawal in a Allogenic Hematopoietic Stem Cell Transplantation Patient". (2018), 61-64. https://doi.org/10.4274/vhd.2018.0001 |
| APA | toka b, EMİNLER A, ASLAN F, KÖKSAL A, Altindis M (2018). A Case of Hepatitis B Reactivation with Acute Flare Three Months After Tenofovir Prophylaxis Withdrawal in a Allogenic Hematopoietic Stem Cell Transplantation Patient. Viral Hepatitis Journal, 24(2), 61 - 64. 10.4274/vhd.2018.0001 |
| Chicago | toka bilal,EMİNLER Ahmet Tarık,ASLAN Ferhat Gürkan,KÖKSAL Aydın Şeref,Altindis Mustafa A Case of Hepatitis B Reactivation with Acute Flare Three Months After Tenofovir Prophylaxis Withdrawal in a Allogenic Hematopoietic Stem Cell Transplantation Patient. Viral Hepatitis Journal 24, no.2 (2018): 61 - 64. 10.4274/vhd.2018.0001 |
| MLA | toka bilal,EMİNLER Ahmet Tarık,ASLAN Ferhat Gürkan,KÖKSAL Aydın Şeref,Altindis Mustafa A Case of Hepatitis B Reactivation with Acute Flare Three Months After Tenofovir Prophylaxis Withdrawal in a Allogenic Hematopoietic Stem Cell Transplantation Patient. Viral Hepatitis Journal, vol.24, no.2, 2018, ss.61 - 64. 10.4274/vhd.2018.0001 |
| AMA | toka b,EMİNLER A,ASLAN F,KÖKSAL A,Altindis M A Case of Hepatitis B Reactivation with Acute Flare Three Months After Tenofovir Prophylaxis Withdrawal in a Allogenic Hematopoietic Stem Cell Transplantation Patient. Viral Hepatitis Journal. 2018; 24(2): 61 - 64. 10.4274/vhd.2018.0001 |
| Vancouver | toka b,EMİNLER A,ASLAN F,KÖKSAL A,Altindis M A Case of Hepatitis B Reactivation with Acute Flare Three Months After Tenofovir Prophylaxis Withdrawal in a Allogenic Hematopoietic Stem Cell Transplantation Patient. Viral Hepatitis Journal. 2018; 24(2): 61 - 64. 10.4274/vhd.2018.0001 |
| IEEE | toka b,EMİNLER A,ASLAN F,KÖKSAL A,Altindis M "A Case of Hepatitis B Reactivation with Acute Flare Three Months After Tenofovir Prophylaxis Withdrawal in a Allogenic Hematopoietic Stem Cell Transplantation Patient." Viral Hepatitis Journal, 24, ss.61 - 64, 2018. 10.4274/vhd.2018.0001 |
| ISNAD | toka, bilal vd. "A Case of Hepatitis B Reactivation with Acute Flare Three Months After Tenofovir Prophylaxis Withdrawal in a Allogenic Hematopoietic Stem Cell Transplantation Patient". Viral Hepatitis Journal 24/2 (2018), 61-64. https://doi.org/10.4274/vhd.2018.0001 |
