TY  - JOUR
TI  - Evaluation and Clinical Significance of Hemogram Parameters in Adrenal Incidentaloma Cases
AB  - Objective Adrenal incidentaloma (AI) are randomly detected masses in magnetic resonance imaging (MRI) or computed tomography (CT) scans taken for different reasons.Although AI is not generally known as an inflammatory clinical condition, its proinflammatory properties have been demonstrated. In this study, we aimed to investigatethe relationship between AI and neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) and its clinical significance.Materialsand MethodsA total of 178 patients who were followed up in the Endocrinology clinic due to AI between January 2018 and December 2019 were retrospectively screened and analyzed.Results The median of NLR and PLR (IQR; 25%-75%) values were 2.21 (1.61; 1.58-3.2) and 112.56 (57.31; 87.81-145.12), respectively. According to tumor locations, median NLR(IQR; 25% -75%) values were 2.24 (1.72; 1.52-3.22) in right-sided AIs, 2.08 (1.14; 1.63-2.77) in left-sided AIs and 2.49 (2.61;1.52-4.13) in bilateral AIs, and no statisticallysignificant difference was found (p=0.172). Likewise, the PLR median (IQR; 25%-75%) was 116.18 (61.1; 88.25-149.35) in right-sided AIs, 102.87 (52.76; 85.01-137.77) inleft-sided AIs and 126.88 (66.7; 95.06-161.76) in bilateral, with no statistically significant difference (p=0.158). There was no statistically significant difference in NLR andPLR in regard of functionally (p=0.357 and p=0.174, respectively). In addition, NLR and PLR results were compared according to presence of hypertension (HT) and nodifference was found (p=0.10 for NLR, p=0.32 for PLR). Of the factors examined in relation to hemogram parameters, only tumor size had a positive but low correlationwith NLR (r=0.199, p=0,01).Conclusion In this study, we found that NLR and PLR did not increase statistically significantly in AI patients. However, there was a positive correlation between tumor size and NLR.It is concluded that although inflammatory hemogram parameters are inexpensive and easily accessible in general, there is no clinical significance in AI patients.
AU  - Varım, Ceyhun
AU  - Cengiz, Hasret
AU  - Demirci, Taner
AU  - DEMİRCİ, ayşe
AU  - Meral, Büşra
AU  - ŞENOCAK, İLYAS ETHEM
DO  - 10.31832/smj.739343
PY  - 2020
JO  - Sakarya Tıp Dergisi
VL  - 10
IS  - 3
SN  - 2146-409X
SP  - 484
EP  - 489
DB  - TRDizin
UR  - http://search/yayin/detay/414563
ER  -