TY  - JOUR
TI  - Is It Possible To Predict Mortality Using Initial Data Of Adult Patients Hospitalized with COVID-19? A Mortality Prediction Model in the Early Phase of COVID-19
AB  - Objective: In this study, we aimed to determine the factors that contribute to the early determination of mortality risk in patients hospitalized with COVID-19.Methods: We included 941 adult inpatients (474 male [50.4%], mean age, 53.5±17.0. The patients were divided into two groups: the discharge group and the death group. Epidemiological data, medical history, underlying comorbidities, laboratory findings, chest computed tomographic scans, real-time reverse transcription polymerase chain reaction detection results, and survival data were obtained with retrospective recordings on admission and follow-up. The statistical relationship between survival data and parameters was analyzed. A mathematical model was created from the data of both groups.Results: While 863 patients survived, 78 were non-survivors. During the study period, the preliminary case fatality rate of the inpatients was 8.3%. The mean age of the non-survivors was 71.7±11.2 SD ( P <0.001). Laboratory findings showed that mortality was high in those with high D-dimer, sodium, lactate dehydrogenase (LDH), troponin, creatine kinase-myocardial band (CK-MB), ferritin, blood lactate, activated partial thromboplastin time, and high blood glucose levels ( P <0.05). Furthermore, mortality was high in patients with low albumin, lymphocyte, and platelet levels ( P <0.05). The logistic regression model showed that advanced age, hypertension, high D-Dimer (>1000 ng/ml), high C-reactive protein (CRP), CK-MB, and LDH, and low lymphocyte count were associated with poor prognosis.Conclusions: According to week 1 data of patients with COVID-19, advanced age, hypertension, D-Dimer, CRP, CK-MB, high LDH, and low lymphocyte were associated with poor prognosis. We believe that this model will be useful in predicting patient mortality.
AU  - Öğütlü, Aziz
AU  - GÜNER, Necip Gökhan
AU  - ÇOKLUK, erdem
AU  - KARABAY, OĞUZ
AU  - Ekerbiçer, Hasan Çetin
AU  - YAYLACI, SELÇUK
AU  - karacan, alper
AU  - Karabay, Meltem
AU  - inci, mustafa baran
AU  - dheir, hamad
AU  - tomak, yakup
AU  - koroglu, mehmet
AU  - Guclu, Ertugrul
DO  - 10.18521/ktd.841884
PY  - 2021
JO  - KONURALP TIP DERGİSİ
VL  - 13
IS  - 1
SN  - 1309-3878
SP  - 36
EP  - 44
DB  - TRDizin
UR  - http://search/yayin/detay/427818
ER  -