TY  - JOUR
TI  - The Relationship Between Insulin Resistance and Trace Elements in Patients With Polycystic Ovary Syndrome
AB  - Objective: The study was investigate serum zinc (Zn),chromium (Cr), cobalt (Co) and manganese (Mn) concentrations in relation to hormone levels and polycystic ovarysyndrome (PCOS).Materials and Methods: Fourty women between 18-40years of age diagnosed with PCOS. We also seleceted 40healty volunteers as the control group. Serum Zn, Cr, Mn,follicular stimulating hormone (FSH), luteinizing hormone(LH), Dehydroepiandrosterone sulfate (DHEA-S), totaltestosterone (TT), sex hormone binding globulin (SHBG),insulin, glucose, cholesterol, triglyceride, High DensityLipoprotein (HDL-C) and Low density lipoprotein (LDLC) concentrations were determined.Results: Insulin, glucose, triglyceride, DHEA-S levelswere significantly higher in the PCOS group than in thecontrol group, while FSH and Mn levels were significantly lower in the HOMA-IR group than in the controlgroup (p< 0.05).Conclusions: A possible association is perceptible in ourstudy between some of serum trace elements and womenwith PCOS. The association attains a connotative levelwith the involvement of IR in it. Additional studies evaluating the effects of these elements supplementation wouldbe required to confirm the hypothesis as well as to ascertain whether insulin resistance in the presence of manganese deficiency can directly lead to oxidative stress.
AU  - Huyut, Zübeyir
AU  - zirek, ali kemal
AU  - balahoroğlu, ragıp
AU  - ÇOKLUK, erdem
AU  - Şekeroğlu, Mehmet Ramazan
AU  - Atmaca, Murat
DO  - 10.26453/otjhs.571510
PY  - 2020
JO  - Online Türk Sağlık Bilimleri Dergisi
VL  - 5
IS  - 2
SN  - 2459-1467
SP  - 375
EP  - 382
DB  - TRDizin
UR  - http://search/yayin/detay/442300
ER  -