TY  - JOUR
TI  - Evaluation of Patients with Fibrotic Interstitial LungDisease: Preliminary results from the Turk-UIP Study
AB  - OBJECTIVE: Differential diagnosis of idiopathic pulmonary fibrosis (IPF) is important among fibrotic interstitial lung diseases (ILD). Thisstudy aimed to evaluate the rate of IPF in patients with fibrotic ILD and to determine the clinical-laboratory features of patients with andwithout IPF that would provide the differential diagnosis of IPF. MATERIAL AND METHODS: The study included the patients with the usual interstitial pneumonia (UIP) pattern or possible UIP patternon thorax high-resolution computed tomography, and/or UIP pattern, probable UIP or possible UIP pattern at lung biopsy according tothe 2011 ATS/ERS/JRS/ALAT guidelines. Demographics and clinical and radiological data of the patients were recorded. All data recordedby researchers was evaluated by radiology and the clinical decision board.RESULTS: A total of 336 patients (253 men, 83 women, age 65.8±9.0 years) were evaluated. Of the patients with sufficient data for diag nosis (n=300), the diagnosis was IPF in 121 (40.3%), unclassified idiopathic interstitial pneumonia in 50 (16.7%), combined pulmonaryfibrosis and emphysema (CPFE) in 40 (13.3%), and lung involvement of connective tissue disease (CTD) in 16 (5.3%). When 29 patientswith definite IPF features were added to the patients with CPFE, the total number of IPF patients reached 150 (50%). Rate of male sex(p<0.001), smoking history (p<0.001), and the presence of clubbing (p=0.001) were significantly high in patients with IPF. None of thewomen <50 years and none of the men <50 years of age without a smoking history were diagnosed with IPF. Presence of at least 1 of thesymptoms suggestive of CTD, erythrocyte sedimentation rate (ESR), and antinuclear antibody (FANA) positivity rates were significantlyhigher in the non-IPF group (p<0.001, p=0.029, p=0.009, respectively).
AU  - Savas, Recep
AU  - OĞUŞ, Candan
AU  - ÖZDEMİR, Özlem KUMBASAR
AU  - ALPER, Fatih
AU  - Uzaslan, Esra
AU  - yazıcı, onur
AU  - Ozgun Niksarlioglu, Elif Yelda
AU  - TOPCU, Füsun
AU  - YILMAZ, Süreyya
AU  - Annakkaya, Ali Nihat
AU  - BAYRAKTAROĞLU, Selen
AU  - FENDOĞLU, Türkan Zeynep
AU  - turktas, haluk
AU  - Salepci, Banu Musaffa
AU  - ÖZSU, Savaş
AU  - KALPAKLIOĞLU, Füsun
AU  - EKİCİ, Aydanur
AU  - Yilmazel Ucar, Elif
AU  - Tertemiz, Kemal Can
AU  - YILMAZ, Bilge KARA
AU  - Turker, Hatice
AU  - EDİS ÇAKIR, Ebru
AU  - Mogulkoc, Nesrin
AU  - Kokturk, Nurdan
AU  - Okumus, Gulfer
AU  - Basyigit, Ilknur
AU  - hanta, ismail
AU  - ATES, GUNGOR
AU  - DEMİR, Ali Arslan
AU  - Tabak, Levent
AU  - KURT, Bahar
AU  - TUNACI, ATADAN
AU  - Altinisik, Goksel
AU  - Musellim, Benan
AU  - Atahan, Ersan
AU  - AKINCI ÖZYÜREK, Berna
AU  - AKYIL TOKGÖZ, Fatma
AU  - Tuncay, Esin
AU  - BİNGÖL, Züleyha
AU  - DIROL, HULYA
AU  - uzun, oğuz
AU  - CAMSARI, Güngör
AU  - SELÇUK, Tuba CAN
AU  - BOZKUŞ, Fülşen
AU  - ZAMANI, Adil
AU  - ERDOĞAN, Yurdanur
AU  - ARGUN, Serap BARIŞ
AU  - AYDEMİR, Yusuf
AU  - ÜZEL, Işıl
AU  - Sevim, Tulin
AU  - KANMAZ, Dilek
AU  - Akcalı  duru, Serap
AU  - HAZAR, Armağan
DO  - 10.5152/TurkThoracJ.2021.20028
PY  - 2021
JO  - Turkish Thoracic Journal
VL  - 22
IS  - 2
SN  - 2149-2530
SP  - 102
EP  - 109
DB  - TRDizin
UR  - http://search/yayin/detay/468008
ER  -