Characteristics and mortality determinants of COVID-19 patients undergoing hemodialysis

dheir, hamad; Gürkan Toçoğlu, Aysel; Bektaş, Melike; mutlu, fuldem; Erdem, Ali Fuat; Açıkgöz, Seyyid Bilal; GENC, AHMED CIHAD; Koroglu, Mehmet; SİPAHİ, Savaş; KARABAY, OĞUZ

Characteristics and mortality determinants of COVID-19 patients undergoing hemodialysis

Savaş SİPAHİ, (Sakarya Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Nefroloji Anabilim Dalı, Sakarya, Türkiye)

Hamad DHEIR, (Sakarya Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Nefroloji Anabilim Dalı, Sakarya, Türkiye)

Aysel TOÇOĞLU, (Sakarya Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Sakarya, Türkiye)

Melike BEKTAŞ, (Sakarya Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Sakarya, Türkiye)

Seyyid Bilal AÇIKGÖZ, (19 Mayıs Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Samsun, Türkiye)

Ahmed Cihad GENÇ, (Sakarya Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Sakarya, Türkiye)

Fuldem MUTLU, (Sakarya Üniversitesi, Tıp Fakültesi, Radyoloji Anabilim Dalı, Sakarya, Türkiye)

Mehmet KÖROĞLU, (Sakarya Üniversitesi, Tıp Fakültesi, Mikrobiyoloji Anabilim Dalı, Sakarya, Türkiye)

Ali Fuat ERDEM, (Sakarya Üniversitesi, Tıp Fakültesi, Anesteziyoloji Anabilim Dalı, Sakarya, Türkiye)

Oğuz KARABAY (Sakarya Üniversitesi, Tıp Fakültesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, Sakarya, Türkiye)

Turkish Journal of Medical Sciences

2 0

Yıl: 2021 Cilt: 51 Sayı: 2 Sayfa Aralığı: 421427 - 421427 Metin Dili: İngilizce İndeks Tarihi: 20-01-2022

Characteristics and mortality determinants of COVID-19 patients undergoing hemodialysis

Öz:

Background/aim: The COVID-19 infection, which started in Wuhan City, China, in December 2019, turned into a pandemic in a very short time, affecting mainly the elderly and those with serious chronic illnesses. COVID-19 infections have been observed to have a high mortality rate, especially in patients undergoing maintenance hemodialysis. Materials and methods: Forty-two patients over 18 years of age who underwent a maintenance hemodialysis program at our unit, who tested positive for COVID-19 by PCR from nasopharyngeal swabs, and/or who were observed to have disease-related signs in their CTs were included in the study. Results: In this study, 23 of 42 patients receiving hemodialysis support in our clinic were included. The median age was 67 years old (min: 35; max: 91 years), and all of our patients had primary hypertension and other comorbidities. Their clinical evaluation showed that dry cough (47.8%) and shortness of breath (47.8%) were the most common symptoms. Fever was less pronounced (30.4%). The median time from the onset of symptoms to hospitalization was 1 day (min: 0; max:), and the time from hospitalization to death was 18 days (min: 1; max: 22). Transfer from the inpatient ward to the ICU took a median of 7 days (min: 1; max: 13). Among the 23 patients, 3 died during follow-up, and 20 were discharged with full recovery. Baseline ferritin, procalcitonin levels, and CRP/albumin rates were higher, and neutrophil/lymphocyte levels were lower in patients who eventually died. In these patients, despite being nonsignificant, there were more diabetic patients, and the D-dimer levels were higher than 1000 ugFEU/L. Conclusion: The COVID-19 infection is associated with increased mortality in chronic kidney diseases patients. Despite being nonsignificant, there was a trend towards increased mortality in patient with diabetes, D-dimer levels >1000 ugFEU/L, higher ferritin and prokalsitonin levels, an increased CRP/albumin ratio, and a lower neutrophil/lymphocyte ratio.Key words: Chronic renal failure, hemodialysis, COVID-19

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	SİPAHİ S, dheir h, Gürkan Toçoğlu A, Bektaş M, Açıkgöz S, GENC A, mutlu f, Koroglu M, Erdem A, KARABAY O (2021). Characteristics and mortality determinants of COVID-19 patients undergoing hemodialysis. , 421427 - 421427.
Chicago	SİPAHİ Savaş,dheir hamad,Gürkan Toçoğlu Aysel,Bektaş Melike,Açıkgöz Seyyid Bilal,GENC AHMED CIHAD,mutlu fuldem,Koroglu Mehmet,Erdem Ali Fuat,KARABAY OĞUZ Characteristics and mortality determinants of COVID-19 patients undergoing hemodialysis. (2021): 421427 - 421427.
MLA	SİPAHİ Savaş,dheir hamad,Gürkan Toçoğlu Aysel,Bektaş Melike,Açıkgöz Seyyid Bilal,GENC AHMED CIHAD,mutlu fuldem,Koroglu Mehmet,Erdem Ali Fuat,KARABAY OĞUZ Characteristics and mortality determinants of COVID-19 patients undergoing hemodialysis. , 2021, ss.421427 - 421427.
AMA	SİPAHİ S,dheir h,Gürkan Toçoğlu A,Bektaş M,Açıkgöz S,GENC A,mutlu f,Koroglu M,Erdem A,KARABAY O Characteristics and mortality determinants of COVID-19 patients undergoing hemodialysis. . 2021; 421427 - 421427.
Vancouver	SİPAHİ S,dheir h,Gürkan Toçoğlu A,Bektaş M,Açıkgöz S,GENC A,mutlu f,Koroglu M,Erdem A,KARABAY O Characteristics and mortality determinants of COVID-19 patients undergoing hemodialysis. . 2021; 421427 - 421427.
IEEE	SİPAHİ S,dheir h,Gürkan Toçoğlu A,Bektaş M,Açıkgöz S,GENC A,mutlu f,Koroglu M,Erdem A,KARABAY O "Characteristics and mortality determinants of COVID-19 patients undergoing hemodialysis." , ss.421427 - 421427, 2021.
ISNAD	SİPAHİ, Savaş vd. "Characteristics and mortality determinants of COVID-19 patients undergoing hemodialysis". (2021), 421427-421427.

APA	SİPAHİ S, dheir h, Gürkan Toçoğlu A, Bektaş M, Açıkgöz S, GENC A, mutlu f, Koroglu M, Erdem A, KARABAY O (2021). Characteristics and mortality determinants of COVID-19 patients undergoing hemodialysis. Turkish Journal of Medical Sciences, 51(2), 421427 - 421427.
Chicago	SİPAHİ Savaş,dheir hamad,Gürkan Toçoğlu Aysel,Bektaş Melike,Açıkgöz Seyyid Bilal,GENC AHMED CIHAD,mutlu fuldem,Koroglu Mehmet,Erdem Ali Fuat,KARABAY OĞUZ Characteristics and mortality determinants of COVID-19 patients undergoing hemodialysis. Turkish Journal of Medical Sciences 51, no.2 (2021): 421427 - 421427.
MLA	SİPAHİ Savaş,dheir hamad,Gürkan Toçoğlu Aysel,Bektaş Melike,Açıkgöz Seyyid Bilal,GENC AHMED CIHAD,mutlu fuldem,Koroglu Mehmet,Erdem Ali Fuat,KARABAY OĞUZ Characteristics and mortality determinants of COVID-19 patients undergoing hemodialysis. Turkish Journal of Medical Sciences, vol.51, no.2, 2021, ss.421427 - 421427.
AMA	SİPAHİ S,dheir h,Gürkan Toçoğlu A,Bektaş M,Açıkgöz S,GENC A,mutlu f,Koroglu M,Erdem A,KARABAY O Characteristics and mortality determinants of COVID-19 patients undergoing hemodialysis. Turkish Journal of Medical Sciences. 2021; 51(2): 421427 - 421427.
Vancouver	SİPAHİ S,dheir h,Gürkan Toçoğlu A,Bektaş M,Açıkgöz S,GENC A,mutlu f,Koroglu M,Erdem A,KARABAY O Characteristics and mortality determinants of COVID-19 patients undergoing hemodialysis. Turkish Journal of Medical Sciences. 2021; 51(2): 421427 - 421427.
IEEE	SİPAHİ S,dheir h,Gürkan Toçoğlu A,Bektaş M,Açıkgöz S,GENC A,mutlu f,Koroglu M,Erdem A,KARABAY O "Characteristics and mortality determinants of COVID-19 patients undergoing hemodialysis." Turkish Journal of Medical Sciences, 51, ss.421427 - 421427, 2021.
ISNAD	SİPAHİ, Savaş vd. "Characteristics and mortality determinants of COVID-19 patients undergoing hemodialysis". Turkish Journal of Medical Sciences 51/2 (2021), 421427-421427.