Efficacy of convalescent plasma according to blood groups in COVID-19 patients

Background/aim: In this study, we aim to investigate the efficacy of convalescent plasma (CP) according to blood groups (BGs) in the treatment of critically ill patients diagnosed with COVID-19. Materials and methods: Twenty-eight critically ill and laboratory-confirmed COVID-19 patients who were admitted to the intensive care unit (ICU) of Sakarya University, Medical Faculty were included in the study. Patients were divided into 2 groups: patients who received anti-A antibody (Ab) containing CP (BG O and B) and those who did not receive CP containing anti-A Ab (BG A and AB). Results: Among the 28 patients, 13 patients received anti-A Ab containing CP (BG; B: 6, O: 7) and 15 patients did not receive anti-A Ab CP (BG; A: 13, AB: 2). Duration in ICU, the rates of mechanical ventilation (MV) support and vasopressor support, the case fatality rate, and the discharge rate were lower in patients who received CP containing anti-A Ab than not containing anti-A Ab CP. However, only the difference in the rate of MV support achieved statistically significance (P = 0.04) Conclusion: In our study, it was observed that the efficiency of CP without anti-A antibody was lower than that of plasma containing anti-A antibody, although it was not statistically significant. This result is thought to be due to the anti-A antibody’s ability to block the ACE2 receptor. We believe that this hypothesis should be investigated in controlled studies with higher patient numbers.Key words: Blood groups, COVID-19, convalescent plasma

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APA	Hacibekiroglu T, Kalpakçı Y, GENC A, hacibekiroglu i, Sunu C, Sarıcaoğlu A, tomak y, KARABAY O, Koroglu M (2021). Efficacy of convalescent plasma according to blood groups in COVID-19 patients. , 45 - 48. 10.3906/sag-2007-59
Chicago	Hacibekiroglu Tuba,Kalpakçı Yasin,GENC AHMED CIHAD,hacibekiroglu ilhan,Sunu Cenk,Sarıcaoğlu Adem,tomak yakup,KARABAY OĞUZ,Koroglu Mehmet Efficacy of convalescent plasma according to blood groups in COVID-19 patients. (2021): 45 - 48. 10.3906/sag-2007-59
MLA	Hacibekiroglu Tuba,Kalpakçı Yasin,GENC AHMED CIHAD,hacibekiroglu ilhan,Sunu Cenk,Sarıcaoğlu Adem,tomak yakup,KARABAY OĞUZ,Koroglu Mehmet Efficacy of convalescent plasma according to blood groups in COVID-19 patients. , 2021, ss.45 - 48. 10.3906/sag-2007-59
AMA	Hacibekiroglu T,Kalpakçı Y,GENC A,hacibekiroglu i,Sunu C,Sarıcaoğlu A,tomak y,KARABAY O,Koroglu M Efficacy of convalescent plasma according to blood groups in COVID-19 patients. . 2021; 45 - 48. 10.3906/sag-2007-59
Vancouver	Hacibekiroglu T,Kalpakçı Y,GENC A,hacibekiroglu i,Sunu C,Sarıcaoğlu A,tomak y,KARABAY O,Koroglu M Efficacy of convalescent plasma according to blood groups in COVID-19 patients. . 2021; 45 - 48. 10.3906/sag-2007-59
IEEE	Hacibekiroglu T,Kalpakçı Y,GENC A,hacibekiroglu i,Sunu C,Sarıcaoğlu A,tomak y,KARABAY O,Koroglu M "Efficacy of convalescent plasma according to blood groups in COVID-19 patients." , ss.45 - 48, 2021. 10.3906/sag-2007-59
ISNAD	Hacibekiroglu, Tuba vd. "Efficacy of convalescent plasma according to blood groups in COVID-19 patients". (2021), 45-48. https://doi.org/10.3906/sag-2007-59

APA	Hacibekiroglu T, Kalpakçı Y, GENC A, hacibekiroglu i, Sunu C, Sarıcaoğlu A, tomak y, KARABAY O, Koroglu M (2021). Efficacy of convalescent plasma according to blood groups in COVID-19 patients. Turkish Journal of Medical Sciences, 51(1), 45 - 48. 10.3906/sag-2007-59
Chicago	Hacibekiroglu Tuba,Kalpakçı Yasin,GENC AHMED CIHAD,hacibekiroglu ilhan,Sunu Cenk,Sarıcaoğlu Adem,tomak yakup,KARABAY OĞUZ,Koroglu Mehmet Efficacy of convalescent plasma according to blood groups in COVID-19 patients. Turkish Journal of Medical Sciences 51, no.1 (2021): 45 - 48. 10.3906/sag-2007-59
MLA	Hacibekiroglu Tuba,Kalpakçı Yasin,GENC AHMED CIHAD,hacibekiroglu ilhan,Sunu Cenk,Sarıcaoğlu Adem,tomak yakup,KARABAY OĞUZ,Koroglu Mehmet Efficacy of convalescent plasma according to blood groups in COVID-19 patients. Turkish Journal of Medical Sciences, vol.51, no.1, 2021, ss.45 - 48. 10.3906/sag-2007-59
AMA	Hacibekiroglu T,Kalpakçı Y,GENC A,hacibekiroglu i,Sunu C,Sarıcaoğlu A,tomak y,KARABAY O,Koroglu M Efficacy of convalescent plasma according to blood groups in COVID-19 patients. Turkish Journal of Medical Sciences. 2021; 51(1): 45 - 48. 10.3906/sag-2007-59
Vancouver	Hacibekiroglu T,Kalpakçı Y,GENC A,hacibekiroglu i,Sunu C,Sarıcaoğlu A,tomak y,KARABAY O,Koroglu M Efficacy of convalescent plasma according to blood groups in COVID-19 patients. Turkish Journal of Medical Sciences. 2021; 51(1): 45 - 48. 10.3906/sag-2007-59
IEEE	Hacibekiroglu T,Kalpakçı Y,GENC A,hacibekiroglu i,Sunu C,Sarıcaoğlu A,tomak y,KARABAY O,Koroglu M "Efficacy of convalescent plasma according to blood groups in COVID-19 patients." Turkish Journal of Medical Sciences, 51, ss.45 - 48, 2021. 10.3906/sag-2007-59
ISNAD	Hacibekiroglu, Tuba vd. "Efficacy of convalescent plasma according to blood groups in COVID-19 patients". Turkish Journal of Medical Sciences 51/1 (2021), 45-48. https://doi.org/10.3906/sag-2007-59