Introduction To investigate the indications and obstetrical characteristics of pregnancy terminations of 10 weeks or more in our clinic. Materials and Methods Between 01/01/2016 and 15/06/2021, 177 cases of pregnancy termination of 10 weeks or more due to any reason were evaluated in our clinic. Results Of the cases included in the study, 153 (86.4%) were early pregnancy termination and 24 (13.6%) were late pregnancy termination. The most common cause of pregnancy terminations was Central nervous system (CNS) anomalies with a frequency of 32.2%. The frequency of anhydramnios was 24.3% and it was the second most frequent reason for pregnancy termination. While Trisomy 21 (12%) was the most common chromosomal abnormality as the cause of pregnancy termination, cardiac anomalies were found the least (0.6%) among structural malformations. No statistically significant difference was found when the early and late termination groups and termination methods were compared among themselves in terms of termination duration. Conclusion CNS anomalies were the most common structural malformations and Trisomy 21 was the most common chromosomal anomalies in cases where pregnancy termination was performed in our clinic.