TY  - JOUR
TI  - Diagnostic precision of C-reactive protein to albumin ratio for coagulopathy in patients with COVID-19
AB  - Purpose: This study aims to assess the diagnostic utility of C-reactive protein (CRP) to albumin ratio (CAR) for predicting elevated D-dimer levels in COVID-19.
Materials and Methods: This retrospective cohort study collected data from 145 hospitalized patients with confirmed COVID-19 in a university hospital. Patients were divided into two groups based on their D-dimer levels, as elevated D‐dimer levels and normal D-dimer levels. Demographic data, comorbidities, clinical symptoms, CAR, and laboratory results were obtained from the patients’ medical records and compared between the groups.
Results: The mean age of patients was 52.9±17.9 years, and 76 of them were male. The median of CAR was significantly higher in those with higher D-dimer (134.1 vs. 20.7). CRP, procalcitonin, leukocyte, neutrophil, lactate dehydrogenase, ferritin, and fibrinogen were higher in patients with elevated D-dimer levels. There was a highly significant positive correlation between CAR and D-Dimer. Logistic regression analysis revealed that CAR was a significant determinant for elevated D‐dimer levels . The area under the ROC curve (AUC) was 0.741 for CAR. The verified cut-off value of CAR for predicting elevated D‐dimer levels in patients with COVID-19 was 81.8, with a sensitivity of 58% and a specificity of 70%. 
Conclusion: Our study revealed that CAR was significantly correlated with D-dimer and can be used to predict elevated D‐dimer levels in patients with COVID-19.
AU  - Guclu, Ertugrul
AU  - Karataş Kılıçcıoğlu, Gizem
AU  - Kaya, Tezcan
AU  - KARABAY, OĞUZ
AU  - İşsever, Kubilay
DO  - 10.17826/cumj.1050419
PY  - 2022
JO  - Cukurova Medical Journal
VL  - 47
IS  - 2
SN  - 2602-3032
SP  - 622
EP  - 628
DB  - TRDizin
UR  - http://search/yayin/detay/524599
ER  -