The investigation of nasal MRSA carriage and colonization of nasopharyngeal pathogens at a primary school in Düzce

KARABAY, OĞUZ; ÖZAYDIN, Çiğdem; ACAR, Selda; BAŞAK, Semra; Şencan, İrfan; Şahin, İdris; yıldırım, mustafa; ÖKSÜZ, Şükrü

The investigation of nasal MRSA carriage and colonization of nasopharyngeal pathogens at a primary school in Düzce

Mustafa YILDIRIM, (Abant İzzet Baysal Üniversitesi, Düzce Tıp Fakültesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, Bolu, Türkiye)

İdris ŞAHİN, (Abant İzzet Baysal Üniversitesi, Düzce Tıp Fakültesi, Mikrobiyoloji ve Klinik Mikrobiyoloji Anabilim Dalı, Bolu, Türkiye)

Semra BAŞAK, (Abant İzzet Baysal Üniversitesi, Düzce Tıp Fakültesi, Mikrobiyoloji ve Klinik Mikrobiyoloji Anabilim Dalı, Bolu, Türkiye)

Şükrü ÖKSÜZ, (Atatürk Eğitim Hastanesi, Mikrobiyoloji ve Klinik Mikrobiyoloji Bölümü, Ankara, Türkiye)

Çiğdem ÖZAYDIN, (Abant İzzet Baysal Üniversitesi, Düzce Tıp Fakültesi, Mikrobiyoloji ve Klinik Mikrobiyoloji Anabilim Dalı, Bolu, Türkiye)

Selda ACAR, (Abant İzzet Baysal Üniversitesi, Düzce Tıp Fakültesi, Mikrobiyoloji ve Klinik Mikrobiyoloji Anabilim Dalı, Bolu, Türkiye)

İrfan ŞENCAN, (Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Bölümü, Ankara, Türkiye)

Oğuz KARABAY (Abant İzzet Baysal Üniversitesi, Düzce Tıp Fakültesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, Bolu, Türkiye)

Turkish Journal of Medical Sciences

1 0

Yıl: 2007 Cilt: 37 Sayı: 6 Sayfa Aralığı: 359 - 365 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

The investigation of nasal MRSA carriage and colonization of nasopharyngeal pathogens at a primary school in Düzce

Öz:

Amaç: Bu çalışmanın amacı sağlıklı okul çocuklarında (6-14 yaş) solunum yolu patojenlerinin nazofaringeal kolonizasyonu ile nasal methicillin-resistant Staphylococcus aureus (MRSA) taşıyıcılığının araştırılmasıdır. Yöntem ve Gereç: Bu çalışma Düzce Üniversitesi tarafından Konuralp ilköğretim okulunda 484 sağlıklı çocukta yapılmıştır. Kültürlerden elde edilen izolatlar klasik mikrobiyolojik yöntemler ve Api 20 strep, NH ile tiplendirildi. Bulgular: Sağlıklı okul çocuklarının %56,6’sında en az bir potansiyel nazofaringeal bakteriyel patojen saptandı. ‹zole edilen bakterilerin %6’sı grup A streptococcus (GAS), %5,0’i S. pneumoniae, %33,1’i M. catarrhalis ve %34,9’u H. inşuenzae idi. İzole edilen GAS türlerinin tamamı penisiline duyarlıydı. S. pneumoniae izolatlarının %8,3’ü penisiline orta düzeyde dirençliydi. Beta-laktamaz testi M. catarrhalis ve H. inşuenzae için sırasıyla, %90,3 ve %8,3 pozitif bulundu. M. catarrhalis’in nazofaringeal kolonizasyonu ile son 6 ay içinde antibiyotik kullanımı (P=0.018) ve H. inşuenzae’nın nazofaringeal kolonizasyonu ile ev içinde antibiyotik kullanımı (P=0.001) arasında anlamlı bir ilişki saptandı. Nazal MRSA taşıyıcılığı sağlıklı çocuklarda %5 bulundu. Bu oran 6-10 yaş grubunda 11-14 yaş grubuna göre daha yüksekti (P=0.012). Sonuç: Okul çocuklarında potansiyel solunum yolu patojenlerinin nazofaringeal taşıyıcılığını göz ardı edilmemelidir ve bu konuda daha gerçekçi bilgilerin elde edilebilmesi için daha kapsamlı sürveyans çalışmaları yapılmalıdır.

Anahtar Kelime:

Konular: Cerrahi

Düzce’de bir ilköğretim okulunda nasal MRSA taşıyıcılığı ve nazofaringeal patojenlerin kolonizasyonunun Araştırılması

Öz:

The aim of the study was to investigate nasopharyngeal colonization of respiratory tract pathogens and nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA) in healthy schoolchildren (6-14 years old).Materials and Methods: The present study was conducted at Konuralp Primary School by Düzce University and 484 healthy children were included. Isolates obtained from nasal and nasopharyngeal cultures were identified by conventional microbiological procedures and Api 20 strep, NH.Results: 56.6% of healthy schoolchildren had at least one nasopharyngeal potential bacterial pathogen. Isolated bacteria species were as follows: 6% group A streptococcus (GAS), 5.0% S. pneumoniae, 33.1% M. catarrhalis, and 34.9% H. influenzae. All of the isolated GAS species were susceptible to penicillin. 8.3% of S. pneumoniae isolates were intermediately resistant to penicillin. Beta-lactamase test was found positive for M. catarrhalis and H. influenzae in 90.3 and 8.3%, respectively. There was a significant relationship between nasopharyngeal colonization of M. catarrhalis and antibiotic usage in the past six months (P=0.018) and nasopharyngeal colonization of H. influenzae and antibiotic usage in the household (P=0.001). The rate of nasal MRSA carriage in healthy children was 5%. This rate was found higher in the 6-10 age group compared to the 11-14 age group (P=0.012).Conclusions: Our data showed that nasopharyngeal carriage of potential respiratory pathogens in schoolchildren should not be underestimated. More comprehensive surveillance studies should be performed to obtain correct information about the carriage.

Anahtar Kelime:

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	yıldırım m, Şahin İ, BAŞAK S, ÖKSÜZ Ş, ÖZAYDIN Ç, ACAR S, Şencan İ, KARABAY O (2007). The investigation of nasal MRSA carriage and colonization of nasopharyngeal pathogens at a primary school in Düzce. , 359 - 365.
Chicago	yıldırım mustafa,Şahin İdris,BAŞAK Semra,ÖKSÜZ Şükrü,ÖZAYDIN Çiğdem,ACAR Selda,Şencan İrfan,KARABAY OĞUZ The investigation of nasal MRSA carriage and colonization of nasopharyngeal pathogens at a primary school in Düzce. (2007): 359 - 365.
MLA	yıldırım mustafa,Şahin İdris,BAŞAK Semra,ÖKSÜZ Şükrü,ÖZAYDIN Çiğdem,ACAR Selda,Şencan İrfan,KARABAY OĞUZ The investigation of nasal MRSA carriage and colonization of nasopharyngeal pathogens at a primary school in Düzce. , 2007, ss.359 - 365.
AMA	yıldırım m,Şahin İ,BAŞAK S,ÖKSÜZ Ş,ÖZAYDIN Ç,ACAR S,Şencan İ,KARABAY O The investigation of nasal MRSA carriage and colonization of nasopharyngeal pathogens at a primary school in Düzce. . 2007; 359 - 365.
Vancouver	yıldırım m,Şahin İ,BAŞAK S,ÖKSÜZ Ş,ÖZAYDIN Ç,ACAR S,Şencan İ,KARABAY O The investigation of nasal MRSA carriage and colonization of nasopharyngeal pathogens at a primary school in Düzce. . 2007; 359 - 365.
IEEE	yıldırım m,Şahin İ,BAŞAK S,ÖKSÜZ Ş,ÖZAYDIN Ç,ACAR S,Şencan İ,KARABAY O "The investigation of nasal MRSA carriage and colonization of nasopharyngeal pathogens at a primary school in Düzce." , ss.359 - 365, 2007.
ISNAD	yıldırım, mustafa vd. "The investigation of nasal MRSA carriage and colonization of nasopharyngeal pathogens at a primary school in Düzce". (2007), 359-365.

APA	yıldırım m, Şahin İ, BAŞAK S, ÖKSÜZ Ş, ÖZAYDIN Ç, ACAR S, Şencan İ, KARABAY O (2007). The investigation of nasal MRSA carriage and colonization of nasopharyngeal pathogens at a primary school in Düzce. Turkish Journal of Medical Sciences, 37(6), 359 - 365.
Chicago	yıldırım mustafa,Şahin İdris,BAŞAK Semra,ÖKSÜZ Şükrü,ÖZAYDIN Çiğdem,ACAR Selda,Şencan İrfan,KARABAY OĞUZ The investigation of nasal MRSA carriage and colonization of nasopharyngeal pathogens at a primary school in Düzce. Turkish Journal of Medical Sciences 37, no.6 (2007): 359 - 365.
MLA	yıldırım mustafa,Şahin İdris,BAŞAK Semra,ÖKSÜZ Şükrü,ÖZAYDIN Çiğdem,ACAR Selda,Şencan İrfan,KARABAY OĞUZ The investigation of nasal MRSA carriage and colonization of nasopharyngeal pathogens at a primary school in Düzce. Turkish Journal of Medical Sciences, vol.37, no.6, 2007, ss.359 - 365.
AMA	yıldırım m,Şahin İ,BAŞAK S,ÖKSÜZ Ş,ÖZAYDIN Ç,ACAR S,Şencan İ,KARABAY O The investigation of nasal MRSA carriage and colonization of nasopharyngeal pathogens at a primary school in Düzce. Turkish Journal of Medical Sciences. 2007; 37(6): 359 - 365.
Vancouver	yıldırım m,Şahin İ,BAŞAK S,ÖKSÜZ Ş,ÖZAYDIN Ç,ACAR S,Şencan İ,KARABAY O The investigation of nasal MRSA carriage and colonization of nasopharyngeal pathogens at a primary school in Düzce. Turkish Journal of Medical Sciences. 2007; 37(6): 359 - 365.
IEEE	yıldırım m,Şahin İ,BAŞAK S,ÖKSÜZ Ş,ÖZAYDIN Ç,ACAR S,Şencan İ,KARABAY O "The investigation of nasal MRSA carriage and colonization of nasopharyngeal pathogens at a primary school in Düzce." Turkish Journal of Medical Sciences, 37, ss.359 - 365, 2007.
ISNAD	yıldırım, mustafa vd. "The investigation of nasal MRSA carriage and colonization of nasopharyngeal pathogens at a primary school in Düzce". Turkish Journal of Medical Sciences 37/6 (2007), 359-365.