Value of neutrophil-to-platelet ratio, immature granulocyte-to-lymphocyte ratio, red blood cell distribution width-to-lymphocyte ratio in differentiating complicated acute appendicitis
Yıl: 2022 Cilt: 28 Sayı: 5 Sayfa Aralığı: 607 - 614 Metin Dili: İngilizce DOI: 10.14744/tjtes.2021.30434 İndeks Tarihi: 07-11-2022
Value of neutrophil-to-platelet ratio, immature granulocyte-to-lymphocyte ratio, red blood cell distribution width-to-lymphocyte ratio in differentiating complicated acute appendicitis
Öz: BACKGROUND: The discovery that medical treatment could be successful in cases with uncomplicated acute appendicitis (UCAA) has revealed the need for successfully differentiating cases with complicated acute appendicitis (CAA). The present study examined the usability of neutrophil-to-platelet ratio (NPR), immature granulocyte-to-lymphocyte ratio, and red blood cell distribution width-to-lymphocyte ratio (RDWLR) in the CAA/UCAA differentiation. METHODS: A retrospective evaluation was made of patients undergoing appendectomy between January 2019 and December 2020. According to pathological and clinical findings, the patients were divided into negative appendectomy, CAA and UCAA groups. Laboratory parameters and associated ratios were evaluated by comparing the groups. RESULTS: The study included 348 patients. Of the patients, 11.2% had CAA, 81.6% had UCAA, and 7.2% had negative appendectomy. The neutrophil-to-lymphocyte ratio (AUC=0.742), platelet-to-lymphocyte ratio (AUC=0.707), immature granulocyte-to-lymphocyte ratio (AUC=0.782), monocyte-to-lymphocyte ratio (AUC=0.720), and RDWLR (AUC=0.711) were found significant in the differentiation between complicated and uncomplicated AA. The NPR (AUC=0.789) was found to be significant in the differentiation between positive and negative appendectomy. CONCLUSION: It was concluded that the immature granulocyte-to-lymphocyte ratio, NPR, monocyte-to-lymphocyte, and RDWLR, which have not been previously studied in patients with acute appendicitis (AA), could be used to differentiate between complicated and uncomplicated AA groups.
Anahtar Kelime: Komplike akut apandisiti ayırt etmede nötrofil-trombosit oranının, immature granülositlenfosit oranının, eritrosit dağılımı genişliği-lenfosit oranının değeri
Öz: AMAÇ: Komplike olmayan akut apandisit olgularında tıbbi tedavi başarısının olabileceğinin anlaşılması üzerine, komplike akut apandisit olgularının başarılı bir şekilde ayırt edilmesi gerekliliği ortaya çıkmıştır. Çalışmamızda, nötrofil/trombosit oranı, immatür granülosit/lenfosit oranı, eritrosit dağılımı genişliği/lenfosit oranı parametrelerinin komplike-komplike olmayan akut apandisit olgularının ayrımındaki kullanılabilirliği irdelemektedir. GEREÇ VE YÖNTEM: Ocak 2019/Aralık 2020 tarihleri arasında apendektomi yapılan hastalar geriye dönük olarak değerlendirildi. Patolojik ve klinik bulgulara göre negatif apendektomi, komplike akut apandisit ve komplike olmayan akut apandisit gruplarına ayrıldı. Laboratuvar parametreleri ve bu parametrelerden elde edilen oranlar gruplar arasında değerlendirildi. BULGULAR: Çalışmaya 348 hasta alındı. Hastaların %11.2’sinin komplike akut apandisit, %81.6’sının komplike olmayan akut apandisit ve %7.2’sinin negatif apendektomi olduğu görüldü. Komplike-komplike olmayan akut apandisit ayrımında; nötrofil/lenfosit oranı (AUC=0.742), trombosit/ lenfosit oranı (AUC=0.707), immatür granülosit/lenfosit oranı (AUC=0.782), monosit/lenfosit oranı (AUC=0.720) ve eritrosit dağılımı genişliği/ lenfosit oranı (AUC=0.711) anlamlı bulundu. Nötrofil/trombosit oranı (AUC=0.789) pozitif apendektomi-negatif apendektomi ayrımında anlamlı bulundu. TARTIŞMA: Daha önce akut apandisit tanılı olgularda çalışılmamış olan immatür granülosit/lenfosit oranı, nötrofil/trombosit oranı, monosit/ lenfosit oranı, eritrosit dağılımı genişliği/lenfosit oranı parametreleri; komplike akut apandisit-komplike olmayan akut apandisit grupları ayrımında kullanılabilir oldukları sonucuna varıldı.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Kubat M, sengul s (2022). Value of neutrophil-to-platelet ratio, immature granulocyte-to-lymphocyte ratio, red blood cell distribution width-to-lymphocyte ratio in differentiating complicated acute appendicitis. , 607 - 614. 10.14744/tjtes.2021.30434 |
| Chicago | Kubat Mehmet,sengul serkan Value of neutrophil-to-platelet ratio, immature granulocyte-to-lymphocyte ratio, red blood cell distribution width-to-lymphocyte ratio in differentiating complicated acute appendicitis. (2022): 607 - 614. 10.14744/tjtes.2021.30434 |
| MLA | Kubat Mehmet,sengul serkan Value of neutrophil-to-platelet ratio, immature granulocyte-to-lymphocyte ratio, red blood cell distribution width-to-lymphocyte ratio in differentiating complicated acute appendicitis. , 2022, ss.607 - 614. 10.14744/tjtes.2021.30434 |
| AMA | Kubat M,sengul s Value of neutrophil-to-platelet ratio, immature granulocyte-to-lymphocyte ratio, red blood cell distribution width-to-lymphocyte ratio in differentiating complicated acute appendicitis. . 2022; 607 - 614. 10.14744/tjtes.2021.30434 |
| Vancouver | Kubat M,sengul s Value of neutrophil-to-platelet ratio, immature granulocyte-to-lymphocyte ratio, red blood cell distribution width-to-lymphocyte ratio in differentiating complicated acute appendicitis. . 2022; 607 - 614. 10.14744/tjtes.2021.30434 |
| IEEE | Kubat M,sengul s "Value of neutrophil-to-platelet ratio, immature granulocyte-to-lymphocyte ratio, red blood cell distribution width-to-lymphocyte ratio in differentiating complicated acute appendicitis." , ss.607 - 614, 2022. 10.14744/tjtes.2021.30434 |
| ISNAD | Kubat, Mehmet - sengul, serkan. "Value of neutrophil-to-platelet ratio, immature granulocyte-to-lymphocyte ratio, red blood cell distribution width-to-lymphocyte ratio in differentiating complicated acute appendicitis". (2022), 607-614. https://doi.org/10.14744/tjtes.2021.30434 |
| APA | Kubat M, sengul s (2022). Value of neutrophil-to-platelet ratio, immature granulocyte-to-lymphocyte ratio, red blood cell distribution width-to-lymphocyte ratio in differentiating complicated acute appendicitis. Ulusal Travma ve Acil Cerrahi Dergisi, 28(5), 607 - 614. 10.14744/tjtes.2021.30434 |
| Chicago | Kubat Mehmet,sengul serkan Value of neutrophil-to-platelet ratio, immature granulocyte-to-lymphocyte ratio, red blood cell distribution width-to-lymphocyte ratio in differentiating complicated acute appendicitis. Ulusal Travma ve Acil Cerrahi Dergisi 28, no.5 (2022): 607 - 614. 10.14744/tjtes.2021.30434 |
| MLA | Kubat Mehmet,sengul serkan Value of neutrophil-to-platelet ratio, immature granulocyte-to-lymphocyte ratio, red blood cell distribution width-to-lymphocyte ratio in differentiating complicated acute appendicitis. Ulusal Travma ve Acil Cerrahi Dergisi, vol.28, no.5, 2022, ss.607 - 614. 10.14744/tjtes.2021.30434 |
| AMA | Kubat M,sengul s Value of neutrophil-to-platelet ratio, immature granulocyte-to-lymphocyte ratio, red blood cell distribution width-to-lymphocyte ratio in differentiating complicated acute appendicitis. Ulusal Travma ve Acil Cerrahi Dergisi. 2022; 28(5): 607 - 614. 10.14744/tjtes.2021.30434 |
| Vancouver | Kubat M,sengul s Value of neutrophil-to-platelet ratio, immature granulocyte-to-lymphocyte ratio, red blood cell distribution width-to-lymphocyte ratio in differentiating complicated acute appendicitis. Ulusal Travma ve Acil Cerrahi Dergisi. 2022; 28(5): 607 - 614. 10.14744/tjtes.2021.30434 |
| IEEE | Kubat M,sengul s "Value of neutrophil-to-platelet ratio, immature granulocyte-to-lymphocyte ratio, red blood cell distribution width-to-lymphocyte ratio in differentiating complicated acute appendicitis." Ulusal Travma ve Acil Cerrahi Dergisi, 28, ss.607 - 614, 2022. 10.14744/tjtes.2021.30434 |
| ISNAD | Kubat, Mehmet - sengul, serkan. "Value of neutrophil-to-platelet ratio, immature granulocyte-to-lymphocyte ratio, red blood cell distribution width-to-lymphocyte ratio in differentiating complicated acute appendicitis". Ulusal Travma ve Acil Cerrahi Dergisi 28/5 (2022), 607-614. https://doi.org/10.14744/tjtes.2021.30434 |
