Applicability of Xpert MTB/RIF assay for routine diagnosis of tuberculosis: a four-year single-center experience

Cem ÇELİK, (Cumhuriyet Üniversitesi, Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Sivas, Türkiye)
Mustafa Gökhan GÖZEL, (Cumhuriyet Üniversitesi Tıp Fakültesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, Sivas, Türkiye)
Mustafa Zahir BAKICI, (Cumhuriyet Üniversitesi, Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Sivas, Türkiye)
Serdar BERK, (Cumhuriyet Üniversitesi, Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, Sivas, Türkiye)
Sefa Levent ÖZŞAHİN, (Cumhuriyet Üniversitesi, Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, Sivas, Türkiye)
Esra GÜLTÜRK (Cumhuriyet Üniversitesi Tıp Fakültesi, Sivas, Türkiye)
Turkish Journal of Medical Sciences
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Yıl: 2015 Cilt: 45 Sayı: 6 Sayfa Aralığı: 1329 - 1334 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Applicability of Xpert MTB/RIF assay for routine diagnosis of tuberculosis: a four-year single-center experience

Öz:
Background/aim: The aim of this study is to assess the Xpert MTB/RIF assay for diagnosis of the Mycobacterium tuberculosis complexin clinical samples and to compare the results by reference to the diagnostic method, Bactec MGIT 960. Materials and methods: A total of 7407 samples were included from patients not primarily suggesting pulmonary or extrapulmonarytuberculosis (TB), collected from patients required to be screened for TB and excluding TB diagnoses since it was a differential diagnosis.Also included were a total of 411 samples from patients primarily suggesting pulmonary or extrapulmonary TB.Results: In the first group, 152 of 7407 samples yielded positive results with the Bactec MGIT 960, 131 (1.77%) were found positivewith Löwenstein Jensen medium, and 295 (3.99%) were found positive with Ziehl Neelsen staining. In the second group, 24 (5.8%), 17(4.1%), and 28 (6.8%) of 411 samples were found positive. Xpert MTB/RIF [27 (6.6%) of 411 samples] detected 3 additional samples aspositive, and these 3 cases were clinically compatible with TB. Conclusion: The Xpert MTB/RIF assay shows superior performance for the diagnosis of TB. Its usefulness in culture-negative patientsand the best method for integrating this diagnostic method into current tuberculosis diagnostic algorithms both need further study.
Anahtar Kelime:

Konular: Cerrahi
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA ÇELİK C, GÖZEL M, BAKICI M, BERK S, ÖZŞAHİN S, gültürk e (2015). Applicability of Xpert MTB/RIF assay for routine diagnosis of tuberculosis: a four-year single-center experience. , 1329 - 1334.
Chicago ÇELİK Cem,GÖZEL Mustafa Gökhan,BAKICI Mustafa Zahir,BERK Serdar,ÖZŞAHİN Sefa Levent,gültürk esra Applicability of Xpert MTB/RIF assay for routine diagnosis of tuberculosis: a four-year single-center experience. (2015): 1329 - 1334.
MLA ÇELİK Cem,GÖZEL Mustafa Gökhan,BAKICI Mustafa Zahir,BERK Serdar,ÖZŞAHİN Sefa Levent,gültürk esra Applicability of Xpert MTB/RIF assay for routine diagnosis of tuberculosis: a four-year single-center experience. , 2015, ss.1329 - 1334.
AMA ÇELİK C,GÖZEL M,BAKICI M,BERK S,ÖZŞAHİN S,gültürk e Applicability of Xpert MTB/RIF assay for routine diagnosis of tuberculosis: a four-year single-center experience. . 2015; 1329 - 1334.
Vancouver ÇELİK C,GÖZEL M,BAKICI M,BERK S,ÖZŞAHİN S,gültürk e Applicability of Xpert MTB/RIF assay for routine diagnosis of tuberculosis: a four-year single-center experience. . 2015; 1329 - 1334.
IEEE ÇELİK C,GÖZEL M,BAKICI M,BERK S,ÖZŞAHİN S,gültürk e "Applicability of Xpert MTB/RIF assay for routine diagnosis of tuberculosis: a four-year single-center experience." , ss.1329 - 1334, 2015.
ISNAD ÇELİK, Cem vd. "Applicability of Xpert MTB/RIF assay for routine diagnosis of tuberculosis: a four-year single-center experience". (2015), 1329-1334.
APA ÇELİK C, GÖZEL M, BAKICI M, BERK S, ÖZŞAHİN S, gültürk e (2015). Applicability of Xpert MTB/RIF assay for routine diagnosis of tuberculosis: a four-year single-center experience. Turkish Journal of Medical Sciences, 45(6), 1329 - 1334.
Chicago ÇELİK Cem,GÖZEL Mustafa Gökhan,BAKICI Mustafa Zahir,BERK Serdar,ÖZŞAHİN Sefa Levent,gültürk esra Applicability of Xpert MTB/RIF assay for routine diagnosis of tuberculosis: a four-year single-center experience. Turkish Journal of Medical Sciences 45, no.6 (2015): 1329 - 1334.
MLA ÇELİK Cem,GÖZEL Mustafa Gökhan,BAKICI Mustafa Zahir,BERK Serdar,ÖZŞAHİN Sefa Levent,gültürk esra Applicability of Xpert MTB/RIF assay for routine diagnosis of tuberculosis: a four-year single-center experience. Turkish Journal of Medical Sciences, vol.45, no.6, 2015, ss.1329 - 1334.
AMA ÇELİK C,GÖZEL M,BAKICI M,BERK S,ÖZŞAHİN S,gültürk e Applicability of Xpert MTB/RIF assay for routine diagnosis of tuberculosis: a four-year single-center experience. Turkish Journal of Medical Sciences. 2015; 45(6): 1329 - 1334.
Vancouver ÇELİK C,GÖZEL M,BAKICI M,BERK S,ÖZŞAHİN S,gültürk e Applicability of Xpert MTB/RIF assay for routine diagnosis of tuberculosis: a four-year single-center experience. Turkish Journal of Medical Sciences. 2015; 45(6): 1329 - 1334.
IEEE ÇELİK C,GÖZEL M,BAKICI M,BERK S,ÖZŞAHİN S,gültürk e "Applicability of Xpert MTB/RIF assay for routine diagnosis of tuberculosis: a four-year single-center experience." Turkish Journal of Medical Sciences, 45, ss.1329 - 1334, 2015.
ISNAD ÇELİK, Cem vd. "Applicability of Xpert MTB/RIF assay for routine diagnosis of tuberculosis: a four-year single-center experience". Turkish Journal of Medical Sciences 45/6 (2015), 1329-1334.
Sayfa Oluşturulma Tarihi
22-04-2024 22:19

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