Yıl: 2015 Cilt: 57 Sayı: 3 Sayfa Aralığı: 233 - 236 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Efficacy of aromatherapy in the treatment of localized alopecia areata: A double-blind placebo controlled study

Öz:
Alopecia areata is an autoimmune disease of the hair follicle which is characterizedby round or oval patches of non-scarring hair loss. In this double-blind randomizedcontrolled study we aimed to evaluate the efficacy of aromatherapy (Revigen®Areata solution) in the treatment of localized alopecia areata. There were twogroups in this study, the aromatherapy group consisted of twenty patientstreated with aromatherapy (essential oils like thyme, rosemary, lavender, eveningprimrose oil and cedrus in a mixture of carrier oils like jojoba, grape seed, almond,lemon and soy oils). The placebo group consisted of 20 patients treated with onlycarrier oils. Each group was treated daily for three months. Hair growth rate (0-4score), clinical assessment (0-4 score) and the size of the affected area (cm2) wereevaluated before the treatment, at the end of the treatment and two months afterthe last treatment. At the end of the follow-up period, mean hair growth rates were2.65±1.37 and 1.11±0.5; and clinical assessment were 2.65±1.28 and 1.11±0.58 inaromatherapy and placebo groups respectively. Mean size of affected area wasdecreased from 6.54±10.18 to 3.40±7.62 in aromatherapy group and 6.73±8.88to 5.30±7.26 in placebo group. All observed differences between these treatmentgroups were statistically significant (p<0.05). Aromatherapy is significantly moreeffective than placebo and safe for the treatment of localized alopecia areata
Anahtar Kelime:

Konular: Genel ve Dahili Tıp

Lokalize alopesi areata tedavisinde aromaterapinin etkinliği: Çift körplacebo kontrollü çalışma

Öz:
Alopecia areata is an autoimmune disease of the hair follicle which is characterized by round or oval patches of non-scarring hair loss. In this double-blind randomized controlled study we aimed to evaluate the efficacy of aromatherapy (Revigen® Areata solution) in the treatment of localized alopecia areata. There were two groups in this study, the aromatherapy group consisted of twenty patients treated with aromatherapy (essential oils like thyme, rosemary, lavender, evening primrose oil and cedrus in a mixture of carrier oils like jojoba, grape seed, almond, lemon and soy oils). The placebo group consisted of 20 patients treated with only carrier oils. Each group was treated daily for three months. Hair growth rate (0-4 score), clinical assessment (0-4 score) and the size of the affected area (cm2) were evaluated before the treatment, at the end of the treatment and two months after the last treatment. At the end of the follow-up period, mean hair growth rates were 2.65±1.37 and 1.11±0.5; and clinical assessment were 2.65±1.28 and 1.11±0.58 in aromatherapy and placebo groups respectively. Mean size of affected area was decreased from 6.54±10.18 to 3.40±7.62 in aromatherapy group and 6.73±8.88 to 5.30±7.26 in placebo group. All observed differences between these treatment groups were statistically significant (p<0.05). Aromatherapy is significantly more effective than placebo and safe for the treatment of localized alopecia areata
Anahtar Kelime:

Konular: Genel ve Dahili Tıp
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • Wasserman D, Guzman-Sanchez DA, Scott K, McMicha- el A. Alopecia areata. Int J Dermatol 2007; 46: 121-31.
  • Madani S, Shapiro J. Alopecia areata update. J Am Acad Dermatol 2000; 42: 549-66.
  • Garg S, Messenger AG. Alopecia areata: evidence-ba- sed treatments. Semin Cutan Med Surg 2009; 28: 15-8.
  • MacDonald Hull SP, Wood ML, Hutchinson PE, Sladden M, Messenger AG. Guidelines for the management of alopecia areata. Br J Dermatol 2003; 149: 692-9.
  • Messenger AG, McKillop J, Farrant P, McDonagh AJ, Sladden M. British Association of Dermatologists' guide- lines for the management of alopecia areata 2012. Br J Dermatol 2012; 166: 916-26.
  • Hay IC, Jamieson M, Ormerod AD. Randomized trial of aromatherapy: successful treatment for alopecia areata. Arch Dermatol 1998; 134: 1349-52.
  • Hajheydari Z, Jamshidi M, Akbari J, Mohammadpour R. Combination of topical garlic gel and betamethasone va- lerate cream in the treatment of localized alopecia areata: a double-blind randomized controlled study. Indian J Der- matol Venereol Leprol 2007; 73: 29-32.
  • Ikeda T. A new classification of alopecia areata. Derma- tologica 1965; 131: 421-45.
  • Tosti A, Bellavista S, Iorizzo M. Alopecia areata: a long term follow-up study of 191 patients. J Am Acad Dermatol 2006; 55: 438-41.
  • Kar BR, Handa S, Dogra S, Kumar B. Placebo-controlled oral pulse prednisolone therapy in alopecia areata. J Am Acad Dermatol 2005; 52: 287-90.
  • Healy E, Rogers S. PUVA treatment for alopecia areata - does it work? A retrospective review of 102 cases. Br J Dermatol 1993; 129: 42-4.
APA ÖZMEN İ, Caliskan E, ARCA E, AÇIKGÖZ G, KOC E (2015). Efficacy of aromatherapy in the treatment of localized alopecia areata: A double-blind placebo controlled study. , 233 - 236.
Chicago ÖZMEN İbrahim,Caliskan Ercan,ARCA ERCAN,AÇIKGÖZ Gürol,KOC EROL Efficacy of aromatherapy in the treatment of localized alopecia areata: A double-blind placebo controlled study. (2015): 233 - 236.
MLA ÖZMEN İbrahim,Caliskan Ercan,ARCA ERCAN,AÇIKGÖZ Gürol,KOC EROL Efficacy of aromatherapy in the treatment of localized alopecia areata: A double-blind placebo controlled study. , 2015, ss.233 - 236.
AMA ÖZMEN İ,Caliskan E,ARCA E,AÇIKGÖZ G,KOC E Efficacy of aromatherapy in the treatment of localized alopecia areata: A double-blind placebo controlled study. . 2015; 233 - 236.
Vancouver ÖZMEN İ,Caliskan E,ARCA E,AÇIKGÖZ G,KOC E Efficacy of aromatherapy in the treatment of localized alopecia areata: A double-blind placebo controlled study. . 2015; 233 - 236.
IEEE ÖZMEN İ,Caliskan E,ARCA E,AÇIKGÖZ G,KOC E "Efficacy of aromatherapy in the treatment of localized alopecia areata: A double-blind placebo controlled study." , ss.233 - 236, 2015.
ISNAD ÖZMEN, İbrahim vd. "Efficacy of aromatherapy in the treatment of localized alopecia areata: A double-blind placebo controlled study". (2015), 233-236.
APA ÖZMEN İ, Caliskan E, ARCA E, AÇIKGÖZ G, KOC E (2015). Efficacy of aromatherapy in the treatment of localized alopecia areata: A double-blind placebo controlled study. Gülhane Tıp Dergisi, 57(3), 233 - 236.
Chicago ÖZMEN İbrahim,Caliskan Ercan,ARCA ERCAN,AÇIKGÖZ Gürol,KOC EROL Efficacy of aromatherapy in the treatment of localized alopecia areata: A double-blind placebo controlled study. Gülhane Tıp Dergisi 57, no.3 (2015): 233 - 236.
MLA ÖZMEN İbrahim,Caliskan Ercan,ARCA ERCAN,AÇIKGÖZ Gürol,KOC EROL Efficacy of aromatherapy in the treatment of localized alopecia areata: A double-blind placebo controlled study. Gülhane Tıp Dergisi, vol.57, no.3, 2015, ss.233 - 236.
AMA ÖZMEN İ,Caliskan E,ARCA E,AÇIKGÖZ G,KOC E Efficacy of aromatherapy in the treatment of localized alopecia areata: A double-blind placebo controlled study. Gülhane Tıp Dergisi. 2015; 57(3): 233 - 236.
Vancouver ÖZMEN İ,Caliskan E,ARCA E,AÇIKGÖZ G,KOC E Efficacy of aromatherapy in the treatment of localized alopecia areata: A double-blind placebo controlled study. Gülhane Tıp Dergisi. 2015; 57(3): 233 - 236.
IEEE ÖZMEN İ,Caliskan E,ARCA E,AÇIKGÖZ G,KOC E "Efficacy of aromatherapy in the treatment of localized alopecia areata: A double-blind placebo controlled study." Gülhane Tıp Dergisi, 57, ss.233 - 236, 2015.
ISNAD ÖZMEN, İbrahim vd. "Efficacy of aromatherapy in the treatment of localized alopecia areata: A double-blind placebo controlled study". Gülhane Tıp Dergisi 57/3 (2015), 233-236.