Laboratory Risk Indicators for Necrotizing Fasciitis and Associations with Mortality

aktimur, recep; KESMER, Sadik; ÖZLEM, Nuraydın; ÇOLAK, Elif; KÜÇÜK, GÜLTEKİN OZAN

Laboratory Risk Indicators for Necrotizing Fasciitis and Associations with Mortality

Elif ÇOLAK, (Department of General Surgery, Samsun Training and Research Hospital, Samsun)

Nuraydın ÖZLEM, (Department of General Surgery, Samsun Training and Research Hospital, Samsun)

GÜLTEKİN OZAN KÜÇÜK, (Department of General Surgery, Samsun Training and Research Hospital, Samsun)

Recep AKTİMUR, (Department of General Surgery, Samsun Training and Research Hospital, Samsun)

Sadik KESMER (Department of General Surgery, Samsun Training and Research Hospital, Samsun)

Türkiye Acil Tıp Dergisi

3 1

Yıl: 2014 Cilt: 14 Sayı: 1 Sayfa Aralığı: 15 - 19 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Laboratory Risk Indicators for Necrotizing Fasciitis and Associations with Mortality

Öz:

Amaç Nekrotizan fasiit (NF) cilt altı dokular ve fasyal planlarda nekrozla karakterize nadir görülen ama hayatı tehdit eden bir yumuşak doku enfeksiyonudur. Nekrotizan fasiit için laboratuvar risk indikatör (LRINEC) skor, NF teşhisinde kullanılan yararlı bir tanısal yöntemdir. Belirli bir LRINEC skor mortalite ile de ilişkili olabilir. Bu çalışmanın amacı NF için LRINEC skorun prognostik değerini ortaya koymak ve prognozu etkileyen risk faktörlerini belirlemektir.Gereç ve YöntemOcak 2008-Nisan 2013 tarihleri arasında Samsun Eğitim ve Araştırma Hastanesi'nde tedavi edilen nekrotizan fasiit tanılı 25 hasta çalışmaya dahil edildi. Yaşayan ve ölen hastalar; demografik özellikler, yandaş hastalıklar, presidpozan faktörler, enfeksiyon etkeni, debridman sayısı ve LRINEC skorlar açısından karşılaştırıldı.BulgularOrtalama yaş 55.6±16.70 yıl (min: 17-maks: 84), kadın/erkek oranı 16/9 idi. Altı (%24) hasta kaybedildi. En sık eşlik eden hastalıklar diabetes mellitus (%52) ve periferik vasküler hastalıklar (%24) idi. En sık etiyoloji ise kutanöz apseler (%32) ve perianal abse (%20) idi. Pseudomanas aeruginosa enfeksiyonu ölen hastalarda daha fazlaydı (p=0.006). Debridman sayısı ortancası ve LRINEC skor ölen hastalarda yaşayan hastalardan anlamlı olarak daha yüksek idi (sırasıyla p=0.003, p=0.003).Sonuç Pseudomanas aeruginosa enfeksiyonu ve çoklu debridmanlar mortalite ile ilişkilidir. LRINEC skror NF için mortaliteyi tahmin etmede kullanılabilir

Anahtar Kelime:

Konular: Cerrahi

Nekrotizan Fasiitli Olgularda Laboratuvar Risk Belirteçleri ve Mortalite ile İlişkisi

Öz:

ObjectivesNecrotizing fasciitis (NF) is rare but life threatening soft tissue infection characterized by a necrotizing process of the subcutaneous tissues and fascial planes. The Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score has been verified as a useful diagnostic tool for detecting necrotizing fasciitis. A certain LRINEC score might also be associated with mortality. The aims of this study are to determine risk factors affecting the prognosis and to evaluate the prognostic value of the LRINEC score in NF.MethodsTwenty-five patients with necrotizing fasciitis treated in Samsun Education and Research Hospital between January 2008 and April 2013 were enrolled in the study. Surviving and non-surviving patient groups were compared regarding demographic data, co-morbidity, predisposing factors, causative agents, number of debridements and LRINEC score.ResultsMean age was 55.6±16.79 years (min: 17-max: 84), and the female/male ratio was 16/9. Mortality was observed in 6 (24%) patients. The most frequent comorbid diseases were diabetes mellitus (52) and peripheral circulatory disorders (24%), and the most frequent etiologies were cutaneous (32%) and perianal abscess (20%). Pseudomonas aeruginosa infection was higher in the non-surviving group (p=0.006). The mean number of debridements and LRINEC score were higher in the non-surviving group than in the surviving group ( p=0.003 and p=0.003, respectively).ConclusionsPseudomans aeruginosa infection and multiple debridements are related with mortality. The LRINEC score might help predict mortality in NF

Anahtar Kelime:

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	ÇOLAK E, ÖZLEM N, KÜÇÜK G, aktimur r, KESMER S (2014). Laboratory Risk Indicators for Necrotizing Fasciitis and Associations with Mortality. , 15 - 19.
Chicago	ÇOLAK Elif,ÖZLEM Nuraydın,KÜÇÜK GÜLTEKİN OZAN,aktimur recep,KESMER Sadik Laboratory Risk Indicators for Necrotizing Fasciitis and Associations with Mortality. (2014): 15 - 19.
MLA	ÇOLAK Elif,ÖZLEM Nuraydın,KÜÇÜK GÜLTEKİN OZAN,aktimur recep,KESMER Sadik Laboratory Risk Indicators for Necrotizing Fasciitis and Associations with Mortality. , 2014, ss.15 - 19.
AMA	ÇOLAK E,ÖZLEM N,KÜÇÜK G,aktimur r,KESMER S Laboratory Risk Indicators for Necrotizing Fasciitis and Associations with Mortality. . 2014; 15 - 19.
Vancouver	ÇOLAK E,ÖZLEM N,KÜÇÜK G,aktimur r,KESMER S Laboratory Risk Indicators for Necrotizing Fasciitis and Associations with Mortality. . 2014; 15 - 19.
IEEE	ÇOLAK E,ÖZLEM N,KÜÇÜK G,aktimur r,KESMER S "Laboratory Risk Indicators for Necrotizing Fasciitis and Associations with Mortality." , ss.15 - 19, 2014.
ISNAD	ÇOLAK, Elif vd. "Laboratory Risk Indicators for Necrotizing Fasciitis and Associations with Mortality". (2014), 15-19.

APA	ÇOLAK E, ÖZLEM N, KÜÇÜK G, aktimur r, KESMER S (2014). Laboratory Risk Indicators for Necrotizing Fasciitis and Associations with Mortality. Türkiye Acil Tıp Dergisi, 14(1), 15 - 19.
Chicago	ÇOLAK Elif,ÖZLEM Nuraydın,KÜÇÜK GÜLTEKİN OZAN,aktimur recep,KESMER Sadik Laboratory Risk Indicators for Necrotizing Fasciitis and Associations with Mortality. Türkiye Acil Tıp Dergisi 14, no.1 (2014): 15 - 19.
MLA	ÇOLAK Elif,ÖZLEM Nuraydın,KÜÇÜK GÜLTEKİN OZAN,aktimur recep,KESMER Sadik Laboratory Risk Indicators for Necrotizing Fasciitis and Associations with Mortality. Türkiye Acil Tıp Dergisi, vol.14, no.1, 2014, ss.15 - 19.
AMA	ÇOLAK E,ÖZLEM N,KÜÇÜK G,aktimur r,KESMER S Laboratory Risk Indicators for Necrotizing Fasciitis and Associations with Mortality. Türkiye Acil Tıp Dergisi. 2014; 14(1): 15 - 19.
Vancouver	ÇOLAK E,ÖZLEM N,KÜÇÜK G,aktimur r,KESMER S Laboratory Risk Indicators for Necrotizing Fasciitis and Associations with Mortality. Türkiye Acil Tıp Dergisi. 2014; 14(1): 15 - 19.
IEEE	ÇOLAK E,ÖZLEM N,KÜÇÜK G,aktimur r,KESMER S "Laboratory Risk Indicators for Necrotizing Fasciitis and Associations with Mortality." Türkiye Acil Tıp Dergisi, 14, ss.15 - 19, 2014.
ISNAD	ÇOLAK, Elif vd. "Laboratory Risk Indicators for Necrotizing Fasciitis and Associations with Mortality". Türkiye Acil Tıp Dergisi 14/1 (2014), 15-19.