Pregabalin is a new generation gabapentinoid that exerts its effect by causing a decrease in the release of neurotransmitters such as glutamate, noradrenaline, and substance P. It is currently used for the treatment of neuropathic pain and fibromyalgia and has anticonvulsant, anxiolytic, and analgesic effects in some conditions. Several case reports and epidemiological studies have raised concern about potential of pregabalin abuse since its use has increased substantially over the last decade. Drug abusers are using it for recreational purposes since it has potential euphoric and dissociative effect when taken in excess of therapeutic doses. The mechanisms behind its abuse potential, , and misuse are not fully known. Furthermore, the age limit has gradually decreased in cases of abuse. In this study, we have presented three adolescent patients with pregabalin abuse who were referred to pediatric emergency outpatient clinic.