Effect of Prostaglandin E1 Analog Misoprostol in An Ovalbumin-Induced Allergic Rhinitis Model
Yıl: 2019 Cilt: 51 Sayı: 1 Sayfa Aralığı: 75 - 79 Metin Dili: İngilizce DOI: 10.5152/eurasianjmed.2019.19025 İndeks Tarihi: 22-04-2020
Effect of Prostaglandin E1 Analog Misoprostol in An Ovalbumin-Induced Allergic Rhinitis Model
Öz: Objective: The aim of the present study was to demonstrate the effects of misoprostol in ovalbumin-induced allergic rhinitis (AR). The second purpose was to compare the effect profile of the combination of an antihistamine with misoprostol during treatment of AR.Materials and Methods: Twenty-five adult male rats were used and were randomly classified into five groups (n=5): healthy+saline, AR, AR and desloratadine (D)-treated group, AR and misoprostol (M)-treated group, and AR and combined-treated group.Results: Desloratadine administration had significantly lower nasal symptoms than the AR group, but nasal symptoms in the AR+M group were better than those in the AR+D group. The best improvement in serum IgE levels was seen in the misoprostol alone and combination treatment groups.Conclusion: We suggest that prostaglandins should be considered in the treatment of AR, and that the effects of these types of drugs should be tested clinically in patients.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | KAYA Z, Yayla M, Bilen A, ATİLLA N, ÖZMEN S, ÇINAR İ, bayraktutan z, Mutlu V, ÜN H, TOKTAY E (2019). Effect of Prostaglandin E1 Analog Misoprostol in An Ovalbumin-Induced Allergic Rhinitis Model. , 75 - 79. 10.5152/eurasianjmed.2019.19025 |
| Chicago | KAYA Zülküf,Yayla Muhammed,Bilen Arzu,ATİLLA Nihal Efe,ÖZMEN SEVİLAY,ÇINAR İRFAN,bayraktutan zafer,Mutlu Vahit,ÜN Harun,TOKTAY Erdem Effect of Prostaglandin E1 Analog Misoprostol in An Ovalbumin-Induced Allergic Rhinitis Model. (2019): 75 - 79. 10.5152/eurasianjmed.2019.19025 |
| MLA | KAYA Zülküf,Yayla Muhammed,Bilen Arzu,ATİLLA Nihal Efe,ÖZMEN SEVİLAY,ÇINAR İRFAN,bayraktutan zafer,Mutlu Vahit,ÜN Harun,TOKTAY Erdem Effect of Prostaglandin E1 Analog Misoprostol in An Ovalbumin-Induced Allergic Rhinitis Model. , 2019, ss.75 - 79. 10.5152/eurasianjmed.2019.19025 |
| AMA | KAYA Z,Yayla M,Bilen A,ATİLLA N,ÖZMEN S,ÇINAR İ,bayraktutan z,Mutlu V,ÜN H,TOKTAY E Effect of Prostaglandin E1 Analog Misoprostol in An Ovalbumin-Induced Allergic Rhinitis Model. . 2019; 75 - 79. 10.5152/eurasianjmed.2019.19025 |
| Vancouver | KAYA Z,Yayla M,Bilen A,ATİLLA N,ÖZMEN S,ÇINAR İ,bayraktutan z,Mutlu V,ÜN H,TOKTAY E Effect of Prostaglandin E1 Analog Misoprostol in An Ovalbumin-Induced Allergic Rhinitis Model. . 2019; 75 - 79. 10.5152/eurasianjmed.2019.19025 |
| IEEE | KAYA Z,Yayla M,Bilen A,ATİLLA N,ÖZMEN S,ÇINAR İ,bayraktutan z,Mutlu V,ÜN H,TOKTAY E "Effect of Prostaglandin E1 Analog Misoprostol in An Ovalbumin-Induced Allergic Rhinitis Model." , ss.75 - 79, 2019. 10.5152/eurasianjmed.2019.19025 |
| ISNAD | KAYA, Zülküf vd. "Effect of Prostaglandin E1 Analog Misoprostol in An Ovalbumin-Induced Allergic Rhinitis Model". (2019), 75-79. https://doi.org/10.5152/eurasianjmed.2019.19025 |
| APA | KAYA Z, Yayla M, Bilen A, ATİLLA N, ÖZMEN S, ÇINAR İ, bayraktutan z, Mutlu V, ÜN H, TOKTAY E (2019). Effect of Prostaglandin E1 Analog Misoprostol in An Ovalbumin-Induced Allergic Rhinitis Model. Eurasian Journal of Medicine, 51(1), 75 - 79. 10.5152/eurasianjmed.2019.19025 |
| Chicago | KAYA Zülküf,Yayla Muhammed,Bilen Arzu,ATİLLA Nihal Efe,ÖZMEN SEVİLAY,ÇINAR İRFAN,bayraktutan zafer,Mutlu Vahit,ÜN Harun,TOKTAY Erdem Effect of Prostaglandin E1 Analog Misoprostol in An Ovalbumin-Induced Allergic Rhinitis Model. Eurasian Journal of Medicine 51, no.1 (2019): 75 - 79. 10.5152/eurasianjmed.2019.19025 |
| MLA | KAYA Zülküf,Yayla Muhammed,Bilen Arzu,ATİLLA Nihal Efe,ÖZMEN SEVİLAY,ÇINAR İRFAN,bayraktutan zafer,Mutlu Vahit,ÜN Harun,TOKTAY Erdem Effect of Prostaglandin E1 Analog Misoprostol in An Ovalbumin-Induced Allergic Rhinitis Model. Eurasian Journal of Medicine, vol.51, no.1, 2019, ss.75 - 79. 10.5152/eurasianjmed.2019.19025 |
| AMA | KAYA Z,Yayla M,Bilen A,ATİLLA N,ÖZMEN S,ÇINAR İ,bayraktutan z,Mutlu V,ÜN H,TOKTAY E Effect of Prostaglandin E1 Analog Misoprostol in An Ovalbumin-Induced Allergic Rhinitis Model. Eurasian Journal of Medicine. 2019; 51(1): 75 - 79. 10.5152/eurasianjmed.2019.19025 |
| Vancouver | KAYA Z,Yayla M,Bilen A,ATİLLA N,ÖZMEN S,ÇINAR İ,bayraktutan z,Mutlu V,ÜN H,TOKTAY E Effect of Prostaglandin E1 Analog Misoprostol in An Ovalbumin-Induced Allergic Rhinitis Model. Eurasian Journal of Medicine. 2019; 51(1): 75 - 79. 10.5152/eurasianjmed.2019.19025 |
| IEEE | KAYA Z,Yayla M,Bilen A,ATİLLA N,ÖZMEN S,ÇINAR İ,bayraktutan z,Mutlu V,ÜN H,TOKTAY E "Effect of Prostaglandin E1 Analog Misoprostol in An Ovalbumin-Induced Allergic Rhinitis Model." Eurasian Journal of Medicine, 51, ss.75 - 79, 2019. 10.5152/eurasianjmed.2019.19025 |
| ISNAD | KAYA, Zülküf vd. "Effect of Prostaglandin E1 Analog Misoprostol in An Ovalbumin-Induced Allergic Rhinitis Model". Eurasian Journal of Medicine 51/1 (2019), 75-79. https://doi.org/10.5152/eurasianjmed.2019.19025 |
