Effect of Comorbid Metabolic Syndrome and Related Components on Cognition in Patients with Schizophrenia
Yıl: 2018 Cilt: 8 Sayı: 4 Sayfa Aralığı: 147 - 157 Metin Dili: İngilizce DOI: 10.5455/PBS.20180530034643 İndeks Tarihi: 07-11-2020
Effect of Comorbid Metabolic Syndrome and Related Components on Cognition in Patients with Schizophrenia
Öz: Objective: The aim of the present study is to compare the cognitive functions of patients with and without metabolic syndrome(MetS) in schizophrenia and schizoaffective disorder, and to investigate the relationship between the clinical symptomatologyand MetS-related components with cognitive functions.Methods: This cross-sectional study included 79 patients diagnosed with schizophrenia/schizoaffective disorder. All participantswere assessed using the Positive PANSS and a neurocognitive battery to assess memory, attention and executive function.Results: In the study group, 35 (44.30%) patients met the criteria for MetS. The MetS group performed worse than thosewithout MetS on verbal memory subtests. There was no difference in attention and executive functioning of the Mets andnon-MetS groups. Multiple regression analyses showed that, elevated HDL were significantly associated with better scoresfor verbal memory, visual memory, and executive functions. In contrast, a higher BMI was significantly associated with poorerscores on visual memory, verbal memory, attention and executive functioning. Unexpectedly, a greater waist circumferencewas associated with better scores for executive functioning.Discussion: MetS and related components are associated with impaired cognitive functioning in patients with schizophrenia/schizoaffective disorder. Early interventions such as reducing risk related BMI values or increasing HDL levels, may reduce riskfactors for MetS and have positive effects on cognitive functioning in patients with schizophrenia.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | ÇELİKBAŞ Z, YILDIZ M, BATMAZ S, YALÇINKAYA ALKAR Ö, KOCAKAYA H (2018). Effect of Comorbid Metabolic Syndrome and Related Components on Cognition in Patients with Schizophrenia. , 147 - 157. 10.5455/PBS.20180530034643 |
| Chicago | ÇELİKBAŞ Zekiye,YILDIZ Mesut,BATMAZ Sedat,YALÇINKAYA ALKAR Özden,KOCAKAYA Hanife Effect of Comorbid Metabolic Syndrome and Related Components on Cognition in Patients with Schizophrenia. (2018): 147 - 157. 10.5455/PBS.20180530034643 |
| MLA | ÇELİKBAŞ Zekiye,YILDIZ Mesut,BATMAZ Sedat,YALÇINKAYA ALKAR Özden,KOCAKAYA Hanife Effect of Comorbid Metabolic Syndrome and Related Components on Cognition in Patients with Schizophrenia. , 2018, ss.147 - 157. 10.5455/PBS.20180530034643 |
| AMA | ÇELİKBAŞ Z,YILDIZ M,BATMAZ S,YALÇINKAYA ALKAR Ö,KOCAKAYA H Effect of Comorbid Metabolic Syndrome and Related Components on Cognition in Patients with Schizophrenia. . 2018; 147 - 157. 10.5455/PBS.20180530034643 |
| Vancouver | ÇELİKBAŞ Z,YILDIZ M,BATMAZ S,YALÇINKAYA ALKAR Ö,KOCAKAYA H Effect of Comorbid Metabolic Syndrome and Related Components on Cognition in Patients with Schizophrenia. . 2018; 147 - 157. 10.5455/PBS.20180530034643 |
| IEEE | ÇELİKBAŞ Z,YILDIZ M,BATMAZ S,YALÇINKAYA ALKAR Ö,KOCAKAYA H "Effect of Comorbid Metabolic Syndrome and Related Components on Cognition in Patients with Schizophrenia." , ss.147 - 157, 2018. 10.5455/PBS.20180530034643 |
| ISNAD | ÇELİKBAŞ, Zekiye vd. "Effect of Comorbid Metabolic Syndrome and Related Components on Cognition in Patients with Schizophrenia". (2018), 147-157. https://doi.org/10.5455/PBS.20180530034643 |
| APA | ÇELİKBAŞ Z, YILDIZ M, BATMAZ S, YALÇINKAYA ALKAR Ö, KOCAKAYA H (2018). Effect of Comorbid Metabolic Syndrome and Related Components on Cognition in Patients with Schizophrenia. Psychiatry and behavioral sciences (Online), 8(4), 147 - 157. 10.5455/PBS.20180530034643 |
| Chicago | ÇELİKBAŞ Zekiye,YILDIZ Mesut,BATMAZ Sedat,YALÇINKAYA ALKAR Özden,KOCAKAYA Hanife Effect of Comorbid Metabolic Syndrome and Related Components on Cognition in Patients with Schizophrenia. Psychiatry and behavioral sciences (Online) 8, no.4 (2018): 147 - 157. 10.5455/PBS.20180530034643 |
| MLA | ÇELİKBAŞ Zekiye,YILDIZ Mesut,BATMAZ Sedat,YALÇINKAYA ALKAR Özden,KOCAKAYA Hanife Effect of Comorbid Metabolic Syndrome and Related Components on Cognition in Patients with Schizophrenia. Psychiatry and behavioral sciences (Online), vol.8, no.4, 2018, ss.147 - 157. 10.5455/PBS.20180530034643 |
| AMA | ÇELİKBAŞ Z,YILDIZ M,BATMAZ S,YALÇINKAYA ALKAR Ö,KOCAKAYA H Effect of Comorbid Metabolic Syndrome and Related Components on Cognition in Patients with Schizophrenia. Psychiatry and behavioral sciences (Online). 2018; 8(4): 147 - 157. 10.5455/PBS.20180530034643 |
| Vancouver | ÇELİKBAŞ Z,YILDIZ M,BATMAZ S,YALÇINKAYA ALKAR Ö,KOCAKAYA H Effect of Comorbid Metabolic Syndrome and Related Components on Cognition in Patients with Schizophrenia. Psychiatry and behavioral sciences (Online). 2018; 8(4): 147 - 157. 10.5455/PBS.20180530034643 |
| IEEE | ÇELİKBAŞ Z,YILDIZ M,BATMAZ S,YALÇINKAYA ALKAR Ö,KOCAKAYA H "Effect of Comorbid Metabolic Syndrome and Related Components on Cognition in Patients with Schizophrenia." Psychiatry and behavioral sciences (Online), 8, ss.147 - 157, 2018. 10.5455/PBS.20180530034643 |
| ISNAD | ÇELİKBAŞ, Zekiye vd. "Effect of Comorbid Metabolic Syndrome and Related Components on Cognition in Patients with Schizophrenia". Psychiatry and behavioral sciences (Online) 8/4 (2018), 147-157. https://doi.org/10.5455/PBS.20180530034643 |
