Siliopatiler ile Birlikte Olan Retina Hastalıkları

Örnek, Nurgül; Örnek, Kemal

Siliopatiler ile Birlikte Olan Retina Hastalıkları

Kemal ÖRNEK, (Kırşehir Ahi Evran Üniversitesi, Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı, Kırşehir, Türkiye)

Nurgül ÖRNEK (Kırıkkale Üniversitesi, Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı, Kırıkkale, Türkiye)

Güncel Retina Dergisi

40 0

Yıl: 2021 Cilt: 5 Sayı: 3 Sayfa Aralığı: 271 - 278 Metin Dili: Türkçe İndeks Tarihi: 05-10-2021

Siliopatiler ile Birlikte Olan Retina Hastalıkları

Öz:

Siliopatiler, silia organeli taşıyan hücreleri etkileyen bir grup hastalıktır. Retina tutulumu sık görülür. Retina fotoreseptörlerinin dış parçaları silialardan oluşmaktadır. Leber doğumsal amarozisi ve retinitis pigmentoza gibi özellikle fotoreseptörlerdeki siliaları etkileyen fonksiyonel bozukluklar sendrom olmayan siliopatiler olarak sınıflandırılır. Usher sendromu,Joubert sendromu, Meckel-Gruber sendromu, Senior-Loken sendromu, Sjögren-Larsson sendromu, Bardet-Biedl sendromuve Alstrom sendromu gibi fotoreseptörler ile birlikte çok sayıda başka dokuların birlikte etkilendiği durumlar ise sendromolan siliopatileri oluşturmaktadır. Bu hastalıklarda altta yatan patolojik mekanizmalar henüz tümüyle aydınlatılmış değildir.Belirtileri güncel yöntemlerle tedavi edilmektedir. Bu yazı, siliopatiye bağlı oluşan retina hastalıklarının oluşumunu, kliniğini, tanı ve tedavilerini anlatmaktadır

Anahtar Kelime:

Retinal Diseases with Ciliopathies

Öz:

Ciliopathies are a group of diseases that affects cells containing the cilia organel. Retinal involvement is frequent in ciliopathies. The outer segment of retinal photoreceptors is composed of cilium. Functional defects limited to the photoreceptors cilia in particular are classified as non-syndromic ciliopathies like Leber congenital amarousis and retinitis pigmentosa. Photoreceptor disease also manifests as a part of syndromic ciliopathies with involvement of multiple tissues as in Usher syndrome, Joubert syndrome, Meckel-Gruber syndrome, Senior-Loken syndrome, Sjögren-Larsson syndrome, Bardet-Biedl syndrome and Alstrom syndrome. Underlying mechanisms of pathology remain largely unclear in these diseases. Symptoms are treated using current methods. This paper describes the pathogenesis, clinics, diagnosis and treatment of retinal diseases occuring due to ciliopathy.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Bibliyografik

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APA	Örnek K, Örnek N (2021). Siliopatiler ile Birlikte Olan Retina Hastalıkları. , 271 - 278.
Chicago	Örnek Kemal,Örnek Nurgül Siliopatiler ile Birlikte Olan Retina Hastalıkları. (2021): 271 - 278.
MLA	Örnek Kemal,Örnek Nurgül Siliopatiler ile Birlikte Olan Retina Hastalıkları. , 2021, ss.271 - 278.
AMA	Örnek K,Örnek N Siliopatiler ile Birlikte Olan Retina Hastalıkları. . 2021; 271 - 278.
Vancouver	Örnek K,Örnek N Siliopatiler ile Birlikte Olan Retina Hastalıkları. . 2021; 271 - 278.
IEEE	Örnek K,Örnek N "Siliopatiler ile Birlikte Olan Retina Hastalıkları." , ss.271 - 278, 2021.
ISNAD	Örnek, Kemal - Örnek, Nurgül. "Siliopatiler ile Birlikte Olan Retina Hastalıkları". (2021), 271-278.

APA	Örnek K, Örnek N (2021). Siliopatiler ile Birlikte Olan Retina Hastalıkları. Güncel Retina Dergisi, 5(3), 271 - 278.
Chicago	Örnek Kemal,Örnek Nurgül Siliopatiler ile Birlikte Olan Retina Hastalıkları. Güncel Retina Dergisi 5, no.3 (2021): 271 - 278.
MLA	Örnek Kemal,Örnek Nurgül Siliopatiler ile Birlikte Olan Retina Hastalıkları. Güncel Retina Dergisi, vol.5, no.3, 2021, ss.271 - 278.
AMA	Örnek K,Örnek N Siliopatiler ile Birlikte Olan Retina Hastalıkları. Güncel Retina Dergisi. 2021; 5(3): 271 - 278.
Vancouver	Örnek K,Örnek N Siliopatiler ile Birlikte Olan Retina Hastalıkları. Güncel Retina Dergisi. 2021; 5(3): 271 - 278.
IEEE	Örnek K,Örnek N "Siliopatiler ile Birlikte Olan Retina Hastalıkları." Güncel Retina Dergisi, 5, ss.271 - 278, 2021.
ISNAD	Örnek, Kemal - Örnek, Nurgül. "Siliopatiler ile Birlikte Olan Retina Hastalıkları". Güncel Retina Dergisi 5/3 (2021), 271-278.