Aims: The purpose of this study was to reveal the opinions, knowledge, and attitudes of parentsin Konya, who refuse vaccination, concerning vaccine refusal. Methods: The study has a cross-sectional design. The research data were collected in 2019using a survey form developed by the researchers. The survey form was filled out by theparents of children in the 0-4 age group who had not been vaccinated in Konya and its districtsin 2017. We were able to reach 801 out of 923 children who had not been vaccinated and stillliving in Konya. The parents of 590 children (73.7%) who agreed to participate in the study wereinterviewed.Results: The most commonly refused type of vaccination was hepatitis A, whereas the leastwas hepatitis B. The most common reasons for vaccine refusal were believing that vaccineswere not safe (63.9%), not believing that vaccines were useful and necessary (57.6%), and nottrusting vaccines because they were produced overseas (47.3%). While 65.9% of the familiesreported that a family health worker tried to convince them to have their children vaccinated,32.4% reported that a family physician tried to convince them. 48.8% of the parents believedthat vaccines caused autism. 70.0% of the parents named their family physician as their sourceof information, 65.4% named internet/social media. Conclusions: The families had difficulty with trusting health workers and disregarded theinformation provided by health workers. Additionally, it was found that gynecologists did notsufficiently inform pregnant women regarding vaccination during the follow-up process.