TY  - JOUR
TI  - The Effect of Delivery Mode on Thiol-Disulfide Balance in the Umbilical Cord Blood
AB  - Purpose: Today, the Oxidative stress level is frequently determined through the methods examining the thiol-disulfide balance. We aimed to compare oxidative stress in elective caesarean sections (ECS) and vaginal deliveries (VD) by examining the thiol-disulfide balance. Materials and methods: Forty- eight VDs and 57 ECSs were included in the study. For standardization, pregnant women who underwent spinal anesthesia for ECS were examined in the study. Five milliliter of blood samples were taken from the umbilical artery immediately after placenta delivery. Serum native thiol, total thiol, disulfide was analyzed in blood samples. Disulfide/native thiol (%), disulfide/total thiol (%), and native thiol/total thiol (%) ratios were calculated. Results: Native thiol, total thiol, disulfide, and disulfide/total thiol ratios were significantly lower in the ECS group than in the VD group (446.27±48.01 vs 484.26±47.50, p<0.001, 493.28±69.14 vs 541.43±64.21, p<0.001, 23.75±9.27 vs. 28.58±11.11, p=0.017, and 4.68±1.48 vs 5.80±2.04, p= 0.002, respectively). There were no differences between the groups in terms of disulfide/native thiol, and native thiol/total thiol ratios (p>0.05). There were no differences between the groups in terms of mean age, gestational week, and birth weight (p>0.05). First and 5th Apgar scores of the newborn of the ECS group were higher than the VD group (p<0.01). Conclusion: The thiol-disulfide balance is affected by delivery mode. The oxidative stress level in vaginal deliveries is higher than in elective caesarean sections.
AU  - Dagli, Recai
AU  - Songur Dagli, Selda
DO  - 10.46332/aemj.841513
PY  - 2021
JO  - Ahi Evran Medical Journal
VL  - 5
IS  - 1
SN  - 2619-9203
SP  - 22
EP  - 27
DB  - TRDizin
UR  - http://search/yayin/detay/493046
ER  -