Kanatlı Salmonella aşılarına farklı perspektiften bakış

Gunaydin, Elcin

Kanatlı Salmonella aşılarına farklı perspektiften bakış

Elçin GÜNAYDIN (Etlik Merkez Veteriner Kontrol ve Araştırma Enstitüsü, Ankara, Türkiye)

Etlik Veteriner Mikrobiyoloji Dergisi

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Yıl: 2008 Cilt: 19 Sayı: 1 Sayfa Aralığı: 63 - 67 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Kanatlı Salmonella aşılarına farklı perspektiften bakış

Öz:

Salmonella infeksiyonlarından korunmada aşılama oldukça güçlü bir araçtır. Daha etkili ve daha güvenli Salmonella aşılarının geliştirilmesine ihtiyaç duyulmaktadır. Salmonella virulensinin genetiği hakkında elde edilen bilgiler ve modern rekombinant DNA teknolojisi; çoklu, belirlenmiş, attenüe ve irreversible mutasyonların bakteri genomu içerisine dahil edilmesi gerekliliği üzerinde durmaktadır. Bu genler bakteriyel yapısal komponentlerin (Lipopolisakkarit; LPS, dış membran proteini; outer membran proteini, OMP) veya temel metabolitlerin (aromatik aminoasit, purin, primidinhistidin) biyosentezinden sorumlu olan ‘house-keeping genes’ olarak adlandırılan genlerdir. Salmonella’nın konak içinde hayatta kalabilmesini sağlayan çok sayıda gen identifiye edilmiştir. Bu genlerde meydana getirilen mutasyonlarla yeni aşı suşları denenmiştir.

Anahtar Kelime: Salmonella aşı(hayvan) amino asitler aşılama (hayvan) virülans kümes hayvanları genetik mühendisliği aşı geliştirme pürin bazları hastalık kontrolü lipopolisakkarit rekombinant DNA histidin

Konular: Biyoloji

View at poultry Salmonella vaccines with different perspective

Öz:

Vaccination is a powerful tool for the protection of Salmonella infections. There is a need to develop more effective and more reliable Salmonella vaccines. The knowledge achieved about the genetics of Salmonella virulence and modern recombinant DNA technology dwell upon a subject of the necessity of inserting multiple, specified, attenued and irreversible mutations into the bacterial genome. These genes, responsible for biosynthesis of bacterial basic structural components (Lipopolisaccharide; LPS, outer membran protein; OMP) or basic metabolits (aromatic aminoasit, purin, primidinhistidin) are termed as house-keeping genes. Many genes, eliciting survival of Salmonella into the host were identified. New vaccine strains were experienced by the mutations achieved in the genes.

Anahtar Kelime: lipopolysaccharides recombinant DNA histidine Salmonella vaccines amino acids vaccination virulence poultry genetic engineering vaccine development purines disease control

Konular: Biyoloji

Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık

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APA	Gunaydin E (2008). Kanatlı Salmonella aşılarına farklı perspektiften bakış. , 63 - 67.
Chicago	Gunaydin Elcin Kanatlı Salmonella aşılarına farklı perspektiften bakış. (2008): 63 - 67.
MLA	Gunaydin Elcin Kanatlı Salmonella aşılarına farklı perspektiften bakış. , 2008, ss.63 - 67.
AMA	Gunaydin E Kanatlı Salmonella aşılarına farklı perspektiften bakış. . 2008; 63 - 67.
Vancouver	Gunaydin E Kanatlı Salmonella aşılarına farklı perspektiften bakış. . 2008; 63 - 67.
IEEE	Gunaydin E "Kanatlı Salmonella aşılarına farklı perspektiften bakış." , ss.63 - 67, 2008.
ISNAD	Gunaydin, Elcin. "Kanatlı Salmonella aşılarına farklı perspektiften bakış". (2008), 63-67.

APA	Gunaydin E (2008). Kanatlı Salmonella aşılarına farklı perspektiften bakış. Etlik Veteriner Mikrobiyoloji Dergisi, 19(1), 63 - 67.
Chicago	Gunaydin Elcin Kanatlı Salmonella aşılarına farklı perspektiften bakış. Etlik Veteriner Mikrobiyoloji Dergisi 19, no.1 (2008): 63 - 67.
MLA	Gunaydin Elcin Kanatlı Salmonella aşılarına farklı perspektiften bakış. Etlik Veteriner Mikrobiyoloji Dergisi, vol.19, no.1, 2008, ss.63 - 67.
AMA	Gunaydin E Kanatlı Salmonella aşılarına farklı perspektiften bakış. Etlik Veteriner Mikrobiyoloji Dergisi. 2008; 19(1): 63 - 67.
Vancouver	Gunaydin E Kanatlı Salmonella aşılarına farklı perspektiften bakış. Etlik Veteriner Mikrobiyoloji Dergisi. 2008; 19(1): 63 - 67.
IEEE	Gunaydin E "Kanatlı Salmonella aşılarına farklı perspektiften bakış." Etlik Veteriner Mikrobiyoloji Dergisi, 19, ss.63 - 67, 2008.
ISNAD	Gunaydin, Elcin. "Kanatlı Salmonella aşılarına farklı perspektiften bakış". Etlik Veteriner Mikrobiyoloji Dergisi 19/1 (2008), 63-67.