The objective of this research is, put forward some people is knowledge, suggestion and opinion about preventing substance abuse and addiction. These people work as a school managers, physical education teachers and guidance teachers at primary schools in Ankara. Research constitutes of 242 school managers, 204 guidance teachers and 200 physical education teachers who work at Altındağ, Çankaya, Etimesgut, Elmadağ, Keçiören, and Yenimahalle in Ankara. All of the data was provided through a questionnaire which was developed by the researchers and was assigned to the participants who are school managers, physical education teachers and guidance teachers. Questionnaire consists of 2 parts. First parts consist of 5 matters which specify the participants’ demographic features. In the second part there are 25 questions related to participants’ knowledge, suggestion and opinion about preventing drug abuse and addiction. Fivefold likert scale was used in the questionnaire, among these distributed ones, 242 of school managers, 204 guidance teachers and 200 physical education teachers, totally 646 questionnaires are seen valid. SPSS 13, 00 statistic packet program was used for evaluating and calculating the collected data. By applying factor analysis to data, questions are grouped in different criteria. According to normality testing, data is seen not normal distribution. Because of this reason, Mann-Whitnet u and Kruskal Wallis h (ANOVA) which are non –parametric tests were used. According to variance homogeneity tukey HSD and LSD test among the post hoc multiple comparision, were used. To look distribution of the demographic variation, percent and frequency counting were made. In this study mistake level was taken as a 0, 05. It is observed that there is no meaningful statistical difference among knowledge, suggestions and opinions for substance abuse and addiction according to gender of the participants. There is a statistical difference among the levels of the knowledge and opinions according to the participants’ professions whereas there is no meaning difference among suggestions.