Objectives: Soft tissue defects of the nose resulting from lesions may cause aesthetic and functionalproblems if they are not properly repaired. Patients and Methods: In this study, a retrospectiveanalysis was conducted of 104 patients (59 females,45 males; mean age 53 years; range 33 to 89 years)who were operated in our clinic between November2005 and July 2009. Nasal soft tissue defects resulting from excision were closed with a primer closurefor 16 patients, a procerius muscle skin flap for 11patients, a nasolabial flap for 26 patients, a dorsalnasal flap for 12 patients, a forehead flap for threepatients, an orbicularis oculi muscle skin flap for threepatients, a V-Y advancement flap for seven patients,a bilateral V-Y advancement flap for one patient, aBanner flap for nine patients, a bilobe flap for eightpatients, an interpolation flap for two patients, a skingraft for 10 patients. Results: We did not observe any occurances of flapnecrosis in any of the patients being treated with skinand muscle skin flaps. After we recognised that twopatients’ excision margins were positive, re-excision wasperformed on them. Tumor recurrence was observed inone patient, and was repaired with skin graft. Conclusion: In this study, we present our successful results in the treatment of soft tissue defects.Reconstructive strategy should be considered fromsimple to more complex planning. Skin flaps shouldbe elevated according to nasal aesthetic units.Which reconstructive technique to employ should bedecided with respect to the localization of the nasaldefect.