Use of GnRH agonist (Desloreline) in combination with $PGF_{2alpha}$ on the termination of pregnancy in bitches
Yıl: 2010 Cilt: 16 Sayı: 6 Sayfa Aralığı: 903 - 908 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022
Use of GnRH agonist (Desloreline) in combination with $PGF_{2alpha}$ on the termination of pregnancy in bitches
Öz: Araştırmada seksüel siklus evresi vaginal sitoloji ile belirlenerek en uygun zamanda çiftleştirilen on dişi köpek kullanıldı. İlk çiftleştirme gününü takiben 20. günden itibaren yapılan ultrases muayenesi ile gebe olduğu belirlenen köpeklere Suprelorin® boyun derisi altına yerleştirildi. İmplantın yerleştirilmesini takiben 10. günde bir kereye mahsus olmak üzere $PGF_{2alpha}$ (cloprostenol, 20 μg/kg,) kas içi yolla uygulandı. Uygulama yapılan köpeklerin tümünde gebelik sonlandı. Progesteron değerinin implantın uygulandığı gün (gebeliğin 20-21. günü), ortalama 28.87±11.86 ng/ml iken, abortion tamamlandığında ortalama 0.43±0.31 ng/ml’ye düştüğü belirlendi. İmplant uygulamasından 10 gün sonra enjekte edilen $PGF_{2alpha}$’yı takiben ortalama 3.9±0,7 günde köpeklerde abortionun tamamlandığı görüldü. Abortionun vajinal akıntının ilk kez görülmesinden sonra 2.3±0.48 gün içinde tamamlandığı belirlendi. Sonuç olarak, uzun etkili GnRH anoloğu olan Deslorelin’in köpeklerde tek doz $PGF_{2alpha}$ uygulaması ile birlikte kombine edildiğinde gebeliği başarılı olarak sonlandırabildiği belirlendi
Anahtar Kelime: Konular:
Köpeklerde gebeliğin sonlandırılması amacıyla GnRH agonisti (Desloreline) ile $PGF_{2alpha}$ kombinasyonunun Kullanımı
Öz: Ten bitches whose sexual cycle periods were determined with vaginal cytology to be mated at appropriate time were used in this study. Desloreline implant (Suprelorin®) was inserted under the dorsal skin of bitches that were determined to be pregnant using ultrasonography 20 days after the first day of mating. Ten days after the implant insertion, single dose $PGF_{2alpha}$ (cloprostenol, 20 μg/kg, IM) was administered. The pregnancy was terminated on all bitches that received this procedure. It was determined that the level of progesterone decreased from an average of 28.87±11.86 ng/ml on the day of implant insertion (day 20-21 of pregnancy) to 0.43±0.31 ng/ml when the abortion was completed. It was observed that after the implant insertion, the abortion was completed in an average of 3.9±0.7 days following $PGF_{2alpha}$ administration. It has been observed that abortions was completed in an average of 2,3±0.48 days after the first vaginal discharge was seen. In conclusion, it was determined that Desloreline, a GnRH agonist, successfully could terminate pregnancy when it is combined with a single dose of $PGF_{2alpha}$ administration in bitches.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | GÜNGÖR Ö, Kaya M, Gürbulak K, ORAL H, kaya s, KACAR C (2010). Use of GnRH agonist (Desloreline) in combination with $PGF_{2alpha}$ on the termination of pregnancy in bitches. , 903 - 908. |
| Chicago | GÜNGÖR Örsan,Kaya Mehmet Demir,Gürbulak Kutlay,ORAL Hasan,kaya semra,KACAR Cihan Use of GnRH agonist (Desloreline) in combination with $PGF_{2alpha}$ on the termination of pregnancy in bitches. (2010): 903 - 908. |
| MLA | GÜNGÖR Örsan,Kaya Mehmet Demir,Gürbulak Kutlay,ORAL Hasan,kaya semra,KACAR Cihan Use of GnRH agonist (Desloreline) in combination with $PGF_{2alpha}$ on the termination of pregnancy in bitches. , 2010, ss.903 - 908. |
| AMA | GÜNGÖR Ö,Kaya M,Gürbulak K,ORAL H,kaya s,KACAR C Use of GnRH agonist (Desloreline) in combination with $PGF_{2alpha}$ on the termination of pregnancy in bitches. . 2010; 903 - 908. |
| Vancouver | GÜNGÖR Ö,Kaya M,Gürbulak K,ORAL H,kaya s,KACAR C Use of GnRH agonist (Desloreline) in combination with $PGF_{2alpha}$ on the termination of pregnancy in bitches. . 2010; 903 - 908. |
| IEEE | GÜNGÖR Ö,Kaya M,Gürbulak K,ORAL H,kaya s,KACAR C "Use of GnRH agonist (Desloreline) in combination with $PGF_{2alpha}$ on the termination of pregnancy in bitches." , ss.903 - 908, 2010. |
| ISNAD | GÜNGÖR, Örsan vd. "Use of GnRH agonist (Desloreline) in combination with $PGF_{2alpha}$ on the termination of pregnancy in bitches". (2010), 903-908. |
| APA | GÜNGÖR Ö, Kaya M, Gürbulak K, ORAL H, kaya s, KACAR C (2010). Use of GnRH agonist (Desloreline) in combination with $PGF_{2alpha}$ on the termination of pregnancy in bitches. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 16(6), 903 - 908. |
| Chicago | GÜNGÖR Örsan,Kaya Mehmet Demir,Gürbulak Kutlay,ORAL Hasan,kaya semra,KACAR Cihan Use of GnRH agonist (Desloreline) in combination with $PGF_{2alpha}$ on the termination of pregnancy in bitches. Kafkas Üniversitesi Veteriner Fakültesi Dergisi 16, no.6 (2010): 903 - 908. |
| MLA | GÜNGÖR Örsan,Kaya Mehmet Demir,Gürbulak Kutlay,ORAL Hasan,kaya semra,KACAR Cihan Use of GnRH agonist (Desloreline) in combination with $PGF_{2alpha}$ on the termination of pregnancy in bitches. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, vol.16, no.6, 2010, ss.903 - 908. |
| AMA | GÜNGÖR Ö,Kaya M,Gürbulak K,ORAL H,kaya s,KACAR C Use of GnRH agonist (Desloreline) in combination with $PGF_{2alpha}$ on the termination of pregnancy in bitches. Kafkas Üniversitesi Veteriner Fakültesi Dergisi. 2010; 16(6): 903 - 908. |
| Vancouver | GÜNGÖR Ö,Kaya M,Gürbulak K,ORAL H,kaya s,KACAR C Use of GnRH agonist (Desloreline) in combination with $PGF_{2alpha}$ on the termination of pregnancy in bitches. Kafkas Üniversitesi Veteriner Fakültesi Dergisi. 2010; 16(6): 903 - 908. |
| IEEE | GÜNGÖR Ö,Kaya M,Gürbulak K,ORAL H,kaya s,KACAR C "Use of GnRH agonist (Desloreline) in combination with $PGF_{2alpha}$ on the termination of pregnancy in bitches." Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 16, ss.903 - 908, 2010. |
| ISNAD | GÜNGÖR, Örsan vd. "Use of GnRH agonist (Desloreline) in combination with $PGF_{2alpha}$ on the termination of pregnancy in bitches". Kafkas Üniversitesi Veteriner Fakültesi Dergisi 16/6 (2010), 903-908. |
