Oral Anticoagulant Use and Long-Term Follow-Up Results in Patients with Non-valvular Atrial Fibrillation in Turkey AFTER-2 Study

Yıl: 2022 Cilt: 26 Sayı: 7 Sayfa Aralığı: 567 - 576 Metin Dili: İngilizce İndeks Tarihi: 09-08-2022

Oral Anticoagulant Use and Long-Term Follow-Up Results in Patients with Non-valvular Atrial Fibrillation in Turkey AFTER-2 Study

Öz:
Background: The aim of this study was to investigate the frequency of oral anticoagulant drugs and time in therapeutic range in patients receiving warfarin in addition to the epi- demiological trial of non-valvular atrial fibrillation previously conducted in Turkey (The Atrial Fibrillation: Epidemiological Registry trial). Furthermore, the prevalence of major adverse events and mortality rates of the patients were evaluated during the long-term follow-up period. Methods: We created a national data registry for non-valvular atrial fibrillation patients, reflecting all geographic regions by population density. In that context, the study included all consecutive atrial fibrillation patients older than 18 years of age who were admitted to the cardiology outpatient clinic except for patients those with prosthetic heart valves and rheumatic mitral valve stenosis. Results: This study included 2592 patients from 35 different centers. The mean age was 68.7 ± 11.1 years, and 55.5% of the patients were female. The most common comorbid diseases were chronic kidney disease (69%) and hypertension (65.5%). The time in ther- apeutic range rate in the general population was 40%, and the mortality rate at 5-year follow-up was 29.4%. Conclusion: The Atrial Fibrillation: Epidemiological Registry 2 study showed higher use of anticoagulant in non-valvular atrial fibrillation patients than in previous national stud- ies. Furthermore, this study demonstrated that most of the non-valvular atrial fibrilla- tion patients are in the high-risk group and the time in therapeutic range rates are still low in Turkey. As a result, this is a significant reason for switching from warfarin to non-K vitamin-dependent new oral anticoagulant treatments.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
APA GÜZEL T, Aktan A, Kılıç R, Arslan B, ARIK B, Yentür M, YILDIZ H, Argun L, İldırımlı K, Yıldırım B, DEMİR M, özbek m, ERTAŞ F (2022). Oral Anticoagulant Use and Long-Term Follow-Up Results in Patients with Non-valvular Atrial Fibrillation in Turkey AFTER-2 Study. , 567 - 576.
Chicago GÜZEL Tuncay,Aktan Adem,Kılıç Raif,Arslan Bayram,ARIK BARAN,Yentür Merve,YILDIZ Halil,Argun Lokman,İldırımlı Kamran,Yıldırım Bünyamin,DEMİR Muhammed,özbek mehmet,ERTAŞ Faruk Oral Anticoagulant Use and Long-Term Follow-Up Results in Patients with Non-valvular Atrial Fibrillation in Turkey AFTER-2 Study. (2022): 567 - 576.
MLA GÜZEL Tuncay,Aktan Adem,Kılıç Raif,Arslan Bayram,ARIK BARAN,Yentür Merve,YILDIZ Halil,Argun Lokman,İldırımlı Kamran,Yıldırım Bünyamin,DEMİR Muhammed,özbek mehmet,ERTAŞ Faruk Oral Anticoagulant Use and Long-Term Follow-Up Results in Patients with Non-valvular Atrial Fibrillation in Turkey AFTER-2 Study. , 2022, ss.567 - 576.
AMA GÜZEL T,Aktan A,Kılıç R,Arslan B,ARIK B,Yentür M,YILDIZ H,Argun L,İldırımlı K,Yıldırım B,DEMİR M,özbek m,ERTAŞ F Oral Anticoagulant Use and Long-Term Follow-Up Results in Patients with Non-valvular Atrial Fibrillation in Turkey AFTER-2 Study. . 2022; 567 - 576.
Vancouver GÜZEL T,Aktan A,Kılıç R,Arslan B,ARIK B,Yentür M,YILDIZ H,Argun L,İldırımlı K,Yıldırım B,DEMİR M,özbek m,ERTAŞ F Oral Anticoagulant Use and Long-Term Follow-Up Results in Patients with Non-valvular Atrial Fibrillation in Turkey AFTER-2 Study. . 2022; 567 - 576.
IEEE GÜZEL T,Aktan A,Kılıç R,Arslan B,ARIK B,Yentür M,YILDIZ H,Argun L,İldırımlı K,Yıldırım B,DEMİR M,özbek m,ERTAŞ F "Oral Anticoagulant Use and Long-Term Follow-Up Results in Patients with Non-valvular Atrial Fibrillation in Turkey AFTER-2 Study." , ss.567 - 576, 2022.
ISNAD GÜZEL, Tuncay vd. "Oral Anticoagulant Use and Long-Term Follow-Up Results in Patients with Non-valvular Atrial Fibrillation in Turkey AFTER-2 Study". (2022), 567-576.
APA GÜZEL T, Aktan A, Kılıç R, Arslan B, ARIK B, Yentür M, YILDIZ H, Argun L, İldırımlı K, Yıldırım B, DEMİR M, özbek m, ERTAŞ F (2022). Oral Anticoagulant Use and Long-Term Follow-Up Results in Patients with Non-valvular Atrial Fibrillation in Turkey AFTER-2 Study. The Anatolian Journal of Cardiology, 26(7), 567 - 576.
Chicago GÜZEL Tuncay,Aktan Adem,Kılıç Raif,Arslan Bayram,ARIK BARAN,Yentür Merve,YILDIZ Halil,Argun Lokman,İldırımlı Kamran,Yıldırım Bünyamin,DEMİR Muhammed,özbek mehmet,ERTAŞ Faruk Oral Anticoagulant Use and Long-Term Follow-Up Results in Patients with Non-valvular Atrial Fibrillation in Turkey AFTER-2 Study. The Anatolian Journal of Cardiology 26, no.7 (2022): 567 - 576.
MLA GÜZEL Tuncay,Aktan Adem,Kılıç Raif,Arslan Bayram,ARIK BARAN,Yentür Merve,YILDIZ Halil,Argun Lokman,İldırımlı Kamran,Yıldırım Bünyamin,DEMİR Muhammed,özbek mehmet,ERTAŞ Faruk Oral Anticoagulant Use and Long-Term Follow-Up Results in Patients with Non-valvular Atrial Fibrillation in Turkey AFTER-2 Study. The Anatolian Journal of Cardiology, vol.26, no.7, 2022, ss.567 - 576.
AMA GÜZEL T,Aktan A,Kılıç R,Arslan B,ARIK B,Yentür M,YILDIZ H,Argun L,İldırımlı K,Yıldırım B,DEMİR M,özbek m,ERTAŞ F Oral Anticoagulant Use and Long-Term Follow-Up Results in Patients with Non-valvular Atrial Fibrillation in Turkey AFTER-2 Study. The Anatolian Journal of Cardiology. 2022; 26(7): 567 - 576.
Vancouver GÜZEL T,Aktan A,Kılıç R,Arslan B,ARIK B,Yentür M,YILDIZ H,Argun L,İldırımlı K,Yıldırım B,DEMİR M,özbek m,ERTAŞ F Oral Anticoagulant Use and Long-Term Follow-Up Results in Patients with Non-valvular Atrial Fibrillation in Turkey AFTER-2 Study. The Anatolian Journal of Cardiology. 2022; 26(7): 567 - 576.
IEEE GÜZEL T,Aktan A,Kılıç R,Arslan B,ARIK B,Yentür M,YILDIZ H,Argun L,İldırımlı K,Yıldırım B,DEMİR M,özbek m,ERTAŞ F "Oral Anticoagulant Use and Long-Term Follow-Up Results in Patients with Non-valvular Atrial Fibrillation in Turkey AFTER-2 Study." The Anatolian Journal of Cardiology, 26, ss.567 - 576, 2022.
ISNAD GÜZEL, Tuncay vd. "Oral Anticoagulant Use and Long-Term Follow-Up Results in Patients with Non-valvular Atrial Fibrillation in Turkey AFTER-2 Study". The Anatolian Journal of Cardiology 26/7 (2022), 567-576.