Yıl: 2021 Cilt: 16 Sayı: 2 Sayfa Aralığı: 131 - 139 Metin Dili: İngilizce DOI: 10.33719/yud.2021;16-2-818890 İndeks Tarihi: 15-08-2022

Retrospective evaluation of our percutaneous biopsy results of renal masses

Öz:
Objective: In this study, we aim to present the retrospective results of percutaneous biopsies per- formed on solid kidney lesions in our clinic with the literature. Materials and Methods: In this retrospective descriptive study approved by the ethics commit- tee in our center, the demographic features and histopathological results of 57 patients who had a solid mass in the kidney between 2017-2020 and underwent ultrasonography-guided percutane- ous kidney biopsy in our interventional radiology clinic were analyzed from the hospital database. Patients without pathology results were excluded from the study. Results: Our patients consisted of 35 men (61,4%) and 23 women (38,6%). The average age was 59.02±15.33(6-94). We had 1 child and 56 adult patients. 29 of the kidney lesions were locat- ed in the left kidney(50,9%) and 28 were located in the right kidney(49,1%). In 44 patients(77.2%) who had malignant pathology; the results were 41 renal cell carcinoma(93.2%), 2 lung squamous cell carcinoma metastasis(4.5%) and 1 primary metastatic pleomorphic adenoma of the salivary gland(2.3%). In a total of 13 patients(22.8%) whose pathology results were benign; the results were 5 oncocytomas(38.5%), 5 angiomyolipo- ma(38.5%), 2 chronic pyelonephritis(15.4%) and 1 metanephric adenoma(7.6%). Renal cell carcino- ma rate was 71.9% among all lesions. Conclusion: Radiological methods may not provide sufficient diagnostic data in the differen- tial diagnosis of solid renal masses.In our study, the rates of benign lesions as a result of percutane- ous biopsy were higher compared to the literature. Therefore, we believe that it is remarkable in terms of the impor- tance of preoperative biopsy in solid lesions.
Anahtar Kelime:

Renal kitle perkütan biyopsi sonuçlarımızın retrospektif incelenmesi

Öz:
Amaç: Bu çalışmada kliniğimizde solid böb- rek lezyonlarına yapılan perkütan biyopsilerinin retrospektif sonuçlarını literatür eşliğinde sunma- yı amaçlıyoruz. Gereç ve Yöntemler: Kendi merkezimizde etik kurulunca onaylanan bu retrospektif tanımla- yıcı çalışmada 2017-2020 yılları arasında böbrek- te solid kitle tespit edilen ve girişimsel radyoloji kliniğimizde ultrasonografi eşliğinde perkütan böbrek biyopsisi yaptığımız 57 hastanın demogra- fik özellikleri ve histopatolojik sonuçları hastane veri tabanından taranarak elde edilen sonuçlar in- celendi. Patoloji sonucu olmayan hastalar çalışma dışı bırakıldı. Bulgular: Hastalarımız 35 erkek (%61,4) ve 22 kadından (%38,6) oluşmaktaydı. Yaş ortala- ması 59,02±15,33 (6-94) idi. 1 çocuk ve 56 erişkin hastamız mevcuttu. Böbrek lezyonlarının 29’u sol böbrek (%50,9), 28’i sağ böbrek (%49,1) yerleşimli idi. Patoloji sonuçları malign olan toplam 44 has- tada (%77,2); 41 renal hücreli karsinom (%93,2), 2 akciğer skuamöz hücreli karsinom metastazı (%4,5) ve 1 primeri bilinen tükrük bezinin metas- taz yapan pleomorfik adenomu (%2,3) ve sonucu benign olan toplam 13 hastada (%22,8) ise; 5 on- kositom (%38,5), 5 anjiomyolipom (%38,5), 2 kro- nik piyelonefrit (%15,4) ve 1 metanefrik adenom (%7,6) olarak elde edildi. Tüm lezyonlar içerisinde renal hücreli karsinom oranı %71,9 olarak bulundu. Sonuç: Tıbbi görüntülemedeki son gelişme- lere rağmen solid renal kitlelerin ayırıcı tanısında radyolojik yöntemler yeterli tanısal veri sağla- mayabilir. Perkütan biyosi sonucunda literatüre kıyasla benign lezyon oranlarının çalışmamızda yüksek olması solid lezyonlarda cerrahi öncesi biyopsinin önemi açısından dikkat çekici olduğunu düşünüyoruz. Ülkemizde geleceğe dönük doğru yaklaşım geliştirebilmemize yar- dımcı olabilecek çok merkezli ve prospektif çalışmalara ihtiyaç ola- cağı kanaatindeyiz.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. Ferlay J, Colombet M, Soerjomataram I, et al. Cancer inci- dence and mortality patterns in Europe: Estimates for 40 countries and 25 major cancers in 2018. Eur J Cancer. 2018; 103:356-87.
  • 2. Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statis- tics 2018: GLOBOCAN estimates of incidence and morta- lity worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018; 68(6):394-424.
  • 3. Novara G, Ficarra V, Antonelli A, et al. Validation of the 2009 TNM version in a large multi-institutional cohort of patients treated for renal cell carcinoma: are further impro- vements needed? Eur Urol. 2010; 58(4):588-595.
  • 4. Patard J-J, Leray E, Rodriguez A, et al. Correlation between Symptom Graduation, Tumor Characteristics and Survival in Renal Cell Carcinoma. Eur Urol. 2003; 44:226-232.
  • 5. O’Connor SD, Pickhardt PJ, Kim DH, et al. Incidental fin- ding of renal masses at unenhanced CT: prevalence and analysis of features for guiding management. AJR Am J Roentgenol. 2011; 197(1):139-45.
  • 6. Cho E, Adami H-O, Lindblad P. Epidemiology of renal cell cancer. Hematol Oncol Clin North Am. 2011; 25(4):651-665.
  • 7. King SC, Pollack LA, Li J, et al. Continued increase in inci- dence of renal cell carcinoma, especially in young patients and high grade disease: United States 2001 to 2010. J Urol. 2014; 191(6):1665-1670.
  • 8. Hollingsworth JM, Miller DC, Daignault S, et al. Rising in- cidence of small renal masses: a need to reassess treatment effect. J Natl Cancer Inst. 2006; 98(18):1331-1334.
  • 9. Cancer Stat Facts: Kidney and Renal Pelvis Cancer: Natio- nal Cancer Institute [online]. 2018. Available from: http:// seer.cancer.gov/statfacts/html/kidrp.html.
  • 10. Frank I, Blute ML, Cheville JC, et al. Solid renal tumors: an analysis of pathological features related to tumor size. J Urol 2003; 170:2217-2220.
  • 11. Kim JH, Sun HY, Hwang J, et al. Diagnostic accuracy of contrast-enhanced computed tomography and cont- rast-enhanced magnetic resonance imaging of small renal masses in real practice: sensitivity and specificity according to subjective radiologic interpretation. World J Surg Oncol. 2016; 14(1):260.
  • 12. Rosenkrantz AB, Hindman N, Fitzgerald EF, et al. MRI features of renal oncocytoma and chromophobe renal cell carcinoma. AJR Am J Roentgenol. 2010; 195(6):421-427.
  • 13. Hindman N, Ngo L, Genega EM, et al. Angiomyolipoma with minimal fat: can it be differentiated from clear cell re- nal cell carcinoma by using standard MR techniques? Ra- diology. 2012; 265:468-477.
  • 14. Patard JJ, Leray E, Rioux-Leclercq N, et al. Prognostic value of histologic subtypes in renal cell carcinoma: a multicenter experience. J Clin Oncol. 2005; 23:2763-2771.
  • 15. Stella M, Chinello C, Cazzaniga A, et al. Histology-guided proteomic analysis to investigate the molecular profiles of clear cell Renal Cell Carcinoma grades. J Proteomics 2019; 191:38-47.
  • 16. Halverson SJ, Kunju LP, Bhalla R, et al. Accuracy of deter- mining small renal mass management with risk stratified biopsies: confirmation by final pathology. J Urol. 2013; 189(2):441-6.
  • 17. Yang CS, Choi E, Idrees MT, et al. Percutaneous biopsy of the renal mass: FNA or core needle biopsy? Cancer Cyto- pathol 2017; 125:407-415.
  • 18. Wang X, Lv Y, Xu Z, et al. Accuracy and safety of ultra- sound-guided percutaneous needle core biopsy of renal masses: A single center experience in China. Medicine (Baltimore). 2018; 97(13):0178.
  • 19. Herrera-Caceres JO, Finelli A, Jewett MAS. Renal tumor biopsy: indicators, technique, safety, accuracy results, and impact on treatment decision management. World J Urol. 2019; 37(3):437-443.
  • 20. Moch H, Cubilla AL, Humphrey PA, et al. The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs-Part A: Renal, Penile, and Testicular Tu- mours. Eur Urol. 2016; 70(1):93-105.
  • 21. Kato M, Suzuki T, Suzuki Y, et al. Natural history of small renal cell carcinoma: evaluation of growth rate, histologi- cal grade, cell proliferation and apoptosis. J Urol. 2004; 172(3):863-866.
  • 22. Sahin M, Canda AE, Mungan MU, et al. Benign lesions un- derwent radical nephrectomy for renal cancer. Turk J Urol. 2004; 30:405-409.
  • 23. Skolarus TA, Serrano MF, Grubb RL, 3rd, et al. Effect of reclassification on the incidence of benign and malignant renal tumors. J Urol. 2010; 183(2):455-458.
  • 24. Kutikov A, Fossett LK, Ramchandani P, et al. Incidence of benign pathologic findings at partial nephrectomy for so- litary renal mass presumed to be renal cell carcinoma on preoperative imaging. Urology. 2006; 68(4):737-740.
  • 25. Lee SH, Park SU, Rha KH, et al. Trends in the incidence of benign pathological lesions at partial nephrectomy for presumed renal cell carcinoma in renal masses on preo- perative computed tomography imaging: a single institute experience with 290 consecutive patients. Int J Urol . 2010; 17:512-516.
  • 26. Bhindi B, Lohse CM, Mason RJ, et al. Are We Using the Best Tumor Size Cut-points for Renal Cell Carcinoma Sta- ging? Urology. 2017; 109:121-126.
  • 27. Welch HG, Skinner JS, Schroeck FR, et al. Regional Varia- tion of Computed Tomographic Imaging in the United Sta- tes and the Risk of Nephrectomy. JAMA Intern Med. 2018; 178(2):221-227.
  • 28. Tamboli P, Ro JY, Amin MB, et al. Benign tumors and tu- mor-like lesions of the adult kidney. Part II: Benign mesen- chymal and mixed neoplasms, and tumor-like lesions. Adv Anat Pathol. 2000; 7(1):47-66.
  • 29. Mei M, Rosen LE, Reddy V, et al. Concurrent angiomyo- lipomas and renal cell neoplasms in patients without tu- berous sclerosis: A retrospective study. Int J Surg Pathol. 2015; 23(4):265-270.
  • 30. Choudhary S, Rajesh A, Mayer NJ, et al. Renal oncocytoma: CT features cannot reliably distinguish oncocytoma from other renal neoplasms. Clin Radiol. 2009; 64(5):517-522.
  • 31. Hosokawa Y, Kinouchi T, Sawai Y, et al. Renal angiomyoli- poma with minimal fat. Int J Clin Oncol. 2002; 7(2):120-123.
  • 32. Silverman SG, Israel GM, Herts BR, et al. Management of the incidental renal mass. Radiology. 2008; 249(1):16-31.
  • 33. Gözükara KH, Rifaioğlu MM. Benign Böbrek Tümörleri. In: Yıldırım A, editor. Böbrek Kanseri Güncelleme. Istan- bul: Türk Üroloji Dernegi; 2016. p. 85-86.
  • 34. Mitnick JS, Bosniak MA, Rothberg M, et al. Metastatic neoplasm to the kidney studied by computed tomography and sonography. J Comput Assist Tomogr. 1985 ;9(1):43-9.
  • 35. Rybicki FJ, Shu KM, Cibas ES, et al. Percutaneous biopsy of renal masses: sensitivity and negative predictive value stratified by clinical setting and size of masses. AJR Am J Roentgenol. 2003; 180(5):1281-1287.
  • 36. Bex A, Albiges L, Ljungberg B, et al. Updated European As- sociation of Urology guidelines regarding adjuvant therapy for renal cell carcinoma. Eur Urol. 2017; 71(5):719-722.
  • 37. Veltri A, Grosso M, Castagneri F, et al. Radiofrequency thermal ablation of small tumors in transplanted kidneys: an evolving nephron-sparing option. J Vasc Interv Radiol. 2009; 20(5):674-679.
  • 38. Volpe A, Mattar K, Finelli A, et al. Contemporary results of percutaneous biopsy of 100 small renal masses: a single center experience. J Urol. 2008; 180(6):2333-2337.
  • 39. Lane BR, Samplaski MK, Herts BR, et al. Renal mass bi- opsy--a renaissance? J Urol. 2008; 179(1):20-27.
  • 40. Caoili EM, Davenport MS. Role of percutaneous need- le biopsy for renal masses. Semin Intervent Radiol. 2014; 31(1):20-26.
  • 41. Appelbaum AH, Kamba TT, Cohen AS, et al. Effectiveness and safety of image-directed biopsies: coaxial technique versus conventional fine-needle aspiration. South Med J. 2002 ;95(2):212-7.
APA Dündar İ, DURMAZ F, özkaçmaz s, KANKILIC N, Kutluhan M, ÖZGÖKÇE M (2021). Retrospective evaluation of our percutaneous biopsy results of renal masses. , 131 - 139. 10.33719/yud.2021;16-2-818890
Chicago Dündar İlyas,DURMAZ FATMA,özkaçmaz sercan,KANKILIC NAZIM A,Kutluhan Musab Ali,ÖZGÖKÇE MESUT Retrospective evaluation of our percutaneous biopsy results of renal masses. (2021): 131 - 139. 10.33719/yud.2021;16-2-818890
MLA Dündar İlyas,DURMAZ FATMA,özkaçmaz sercan,KANKILIC NAZIM A,Kutluhan Musab Ali,ÖZGÖKÇE MESUT Retrospective evaluation of our percutaneous biopsy results of renal masses. , 2021, ss.131 - 139. 10.33719/yud.2021;16-2-818890
AMA Dündar İ,DURMAZ F,özkaçmaz s,KANKILIC N,Kutluhan M,ÖZGÖKÇE M Retrospective evaluation of our percutaneous biopsy results of renal masses. . 2021; 131 - 139. 10.33719/yud.2021;16-2-818890
Vancouver Dündar İ,DURMAZ F,özkaçmaz s,KANKILIC N,Kutluhan M,ÖZGÖKÇE M Retrospective evaluation of our percutaneous biopsy results of renal masses. . 2021; 131 - 139. 10.33719/yud.2021;16-2-818890
IEEE Dündar İ,DURMAZ F,özkaçmaz s,KANKILIC N,Kutluhan M,ÖZGÖKÇE M "Retrospective evaluation of our percutaneous biopsy results of renal masses." , ss.131 - 139, 2021. 10.33719/yud.2021;16-2-818890
ISNAD Dündar, İlyas vd. "Retrospective evaluation of our percutaneous biopsy results of renal masses". (2021), 131-139. https://doi.org/10.33719/yud.2021;16-2-818890
APA Dündar İ, DURMAZ F, özkaçmaz s, KANKILIC N, Kutluhan M, ÖZGÖKÇE M (2021). Retrospective evaluation of our percutaneous biopsy results of renal masses. Yeni Üroloji Dergisi, 16(2), 131 - 139. 10.33719/yud.2021;16-2-818890
Chicago Dündar İlyas,DURMAZ FATMA,özkaçmaz sercan,KANKILIC NAZIM A,Kutluhan Musab Ali,ÖZGÖKÇE MESUT Retrospective evaluation of our percutaneous biopsy results of renal masses. Yeni Üroloji Dergisi 16, no.2 (2021): 131 - 139. 10.33719/yud.2021;16-2-818890
MLA Dündar İlyas,DURMAZ FATMA,özkaçmaz sercan,KANKILIC NAZIM A,Kutluhan Musab Ali,ÖZGÖKÇE MESUT Retrospective evaluation of our percutaneous biopsy results of renal masses. Yeni Üroloji Dergisi, vol.16, no.2, 2021, ss.131 - 139. 10.33719/yud.2021;16-2-818890
AMA Dündar İ,DURMAZ F,özkaçmaz s,KANKILIC N,Kutluhan M,ÖZGÖKÇE M Retrospective evaluation of our percutaneous biopsy results of renal masses. Yeni Üroloji Dergisi. 2021; 16(2): 131 - 139. 10.33719/yud.2021;16-2-818890
Vancouver Dündar İ,DURMAZ F,özkaçmaz s,KANKILIC N,Kutluhan M,ÖZGÖKÇE M Retrospective evaluation of our percutaneous biopsy results of renal masses. Yeni Üroloji Dergisi. 2021; 16(2): 131 - 139. 10.33719/yud.2021;16-2-818890
IEEE Dündar İ,DURMAZ F,özkaçmaz s,KANKILIC N,Kutluhan M,ÖZGÖKÇE M "Retrospective evaluation of our percutaneous biopsy results of renal masses." Yeni Üroloji Dergisi, 16, ss.131 - 139, 2021. 10.33719/yud.2021;16-2-818890
ISNAD Dündar, İlyas vd. "Retrospective evaluation of our percutaneous biopsy results of renal masses". Yeni Üroloji Dergisi 16/2 (2021), 131-139. https://doi.org/10.33719/yud.2021;16-2-818890