Characterization of Nanoparticles Containing Achillea Phrygia and Their Antioxidant and Antiproliferative Properties

TAŞKIN, Duygu; Doğan, Murat; ARABACI, Turan; Ermanoğlu, Mizgin

doi:10.17776/csj.1056496

Characterization of Nanoparticles Containing Achillea Phrygia and Their Antioxidant and Antiproliferative Properties

Murat DOĞAN, (Sivas Cumhuriyet Üniversitesi, Eczacılık Fakültesi, Farmasötik Biyoteknoloji Anabilim Dalı, Sivas, Türkiye)

Duygu TAŞKIN, (Sağlık Bilimleri Üniversitesi, Eczacılık Fakültesi, Analitik Kimya Anabilim Dalı, İstanbul, Türkiye)

Mizgin ERMANOĞLU, (Marmara Üniversitesi, Eczacılık Fakültesi, Farmakognozi Anabilim Dalı, İstanbul, Türkiye)

Turan ARABACI (İnönü Üniversitesi, Eczacılık Fakültesi, Farmasötik Botanik Anabilim Dalı, Malatya, Türkiye)

Cumhuriyet Science Journal

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Yıl: 2022 Cilt: 43 Sayı: 1 Sayfa Aralığı: 27 - 32 Metin Dili: İngilizce DOI: 10.17776/csj.1056496 İndeks Tarihi: 22-08-2022

Characterization of Nanoparticles Containing Achillea Phrygia and Their Antioxidant and Antiproliferative Properties

Öz:

In this study, antioxidant and antiproliferative properties of ‘‘Achillea phrygia’’ were investigated. Since the antioxidant and antiproliferative activity of B sub-extract from plant’s chloroform extract is higher than other extracts, B sub-extract of Achillea phrygia was used in the preparation of nanoparticles. Characterization of nanoparticles was made, antiproliferative activities and IC50 values of nanoparticles and only chloroform extract was calculated by cell culture studies and XTT cell viability test. According to the results, it was observed that the extract-loaded chitosan nanoparticles had a strong antiproliferative activity in both MCF 7 and HT29 cells. The results of this study support that bioactive extract of the Achillea phrygia plant can be prepared as an herbal medicine candidate by preparing formulations with biopolymers and being investigated in cancer studies.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Doğan M, TAŞKIN D, Ermanoğlu M, ARABACI T (2022). Characterization of Nanoparticles Containing Achillea Phrygia and Their Antioxidant and Antiproliferative Properties. , 27 - 32. 10.17776/csj.1056496
Chicago	Doğan Murat,TAŞKIN Duygu,Ermanoğlu Mizgin,ARABACI Turan Characterization of Nanoparticles Containing Achillea Phrygia and Their Antioxidant and Antiproliferative Properties. (2022): 27 - 32. 10.17776/csj.1056496
MLA	Doğan Murat,TAŞKIN Duygu,Ermanoğlu Mizgin,ARABACI Turan Characterization of Nanoparticles Containing Achillea Phrygia and Their Antioxidant and Antiproliferative Properties. , 2022, ss.27 - 32. 10.17776/csj.1056496
AMA	Doğan M,TAŞKIN D,Ermanoğlu M,ARABACI T Characterization of Nanoparticles Containing Achillea Phrygia and Their Antioxidant and Antiproliferative Properties. . 2022; 27 - 32. 10.17776/csj.1056496
Vancouver	Doğan M,TAŞKIN D,Ermanoğlu M,ARABACI T Characterization of Nanoparticles Containing Achillea Phrygia and Their Antioxidant and Antiproliferative Properties. . 2022; 27 - 32. 10.17776/csj.1056496
IEEE	Doğan M,TAŞKIN D,Ermanoğlu M,ARABACI T "Characterization of Nanoparticles Containing Achillea Phrygia and Their Antioxidant and Antiproliferative Properties." , ss.27 - 32, 2022. 10.17776/csj.1056496
ISNAD	Doğan, Murat vd. "Characterization of Nanoparticles Containing Achillea Phrygia and Their Antioxidant and Antiproliferative Properties". (2022), 27-32. https://doi.org/10.17776/csj.1056496

APA	Doğan M, TAŞKIN D, Ermanoğlu M, ARABACI T (2022). Characterization of Nanoparticles Containing Achillea Phrygia and Their Antioxidant and Antiproliferative Properties. Cumhuriyet Science Journal, 43(1), 27 - 32. 10.17776/csj.1056496
Chicago	Doğan Murat,TAŞKIN Duygu,Ermanoğlu Mizgin,ARABACI Turan Characterization of Nanoparticles Containing Achillea Phrygia and Their Antioxidant and Antiproliferative Properties. Cumhuriyet Science Journal 43, no.1 (2022): 27 - 32. 10.17776/csj.1056496
MLA	Doğan Murat,TAŞKIN Duygu,Ermanoğlu Mizgin,ARABACI Turan Characterization of Nanoparticles Containing Achillea Phrygia and Their Antioxidant and Antiproliferative Properties. Cumhuriyet Science Journal, vol.43, no.1, 2022, ss.27 - 32. 10.17776/csj.1056496
AMA	Doğan M,TAŞKIN D,Ermanoğlu M,ARABACI T Characterization of Nanoparticles Containing Achillea Phrygia and Their Antioxidant and Antiproliferative Properties. Cumhuriyet Science Journal. 2022; 43(1): 27 - 32. 10.17776/csj.1056496
Vancouver	Doğan M,TAŞKIN D,Ermanoğlu M,ARABACI T Characterization of Nanoparticles Containing Achillea Phrygia and Their Antioxidant and Antiproliferative Properties. Cumhuriyet Science Journal. 2022; 43(1): 27 - 32. 10.17776/csj.1056496
IEEE	Doğan M,TAŞKIN D,Ermanoğlu M,ARABACI T "Characterization of Nanoparticles Containing Achillea Phrygia and Their Antioxidant and Antiproliferative Properties." Cumhuriyet Science Journal, 43, ss.27 - 32, 2022. 10.17776/csj.1056496
ISNAD	Doğan, Murat vd. "Characterization of Nanoparticles Containing Achillea Phrygia and Their Antioxidant and Antiproliferative Properties". Cumhuriyet Science Journal 43/1 (2022), 27-32. https://doi.org/10.17776/csj.1056496