TY - JOUR TI - COVID-19 Vaccines Can Initiate or Exacerbate A Rheumatic Disease; A Report of 4 Cases AB - Vaccination has been playing an anchor role in controlling the COVID-19 pandemic. Notably, mRNA-based novel vaccines against SARS-CoV2 have increased some speculations among rheumatologists and patients with autoimmune disorders, whether they may reactivate the presenting disease or unveil a new autoimmune disease because of the absence of randomized controlled tirals pioneering their effects in this specific population. Despite these theoretical concerns on immune hyperactivation, vaccination has been performed widespreadly because benefits outweigh mortality risks in this population. Recent observational studies showed that disease flares are seen in rheumatic diseases after vaccination. On the other hand, case reports and case series have been increasingly published that autoimmune disorders may be emerged following vaccination. Herein, we report 4 cases including flares and an occurence of rheumatic disease after mRNA vaccination. AU - Dinler, Mustafa AU - ÜSKÜDAR CANSU, Döndü AU - YILDIRIM, REŞİT AU - korkmaz, cengiz DO - 10.20515/otd.1035188 PY - 2022 JO - Osmangazi Tıp Dergisi VL - 44 IS - 4 SN - 1305-4953 SP - 576 EP - 579 DB - TRDizin UR - http://search/yayin/detay/1118898 ER -