Comparison of APACHE II and Modified Charlson Index in Mortality Prediction in Patients at Medical Intensive Care Unit

KAPLAN EFE, FATMA; IYNEM, Hatice Kevser; Beyan, Esin; Bulur, Oktay; KOC, SULEYMAN

doi:10.20515/otd.997570

Comparison of APACHE II and Modified Charlson Index in Mortality Prediction in Patients at Medical Intensive Care Unit

Oktay BULUR, (Sağlık Bilimleri Üniversitesi, Keçiören Eğitim ve Araştırma Hastanesi, Dahiliye Kliniği, Ankara, Türkiye)

Fatma KAPLAN EFE, (Sağlık Bilimleri Üniversitesi, Keçiören Eğitim ve Araştırma Hastanesi, Dahiliye Kliniği, Ankara, Türkiye)

Hatice Kevser IYNEM, (Sağlık Bilimleri Üniversitesi, Keçiören Eğitim ve Araştırma Hastanesi, Dahiliye Kliniği, Ankara, Türkiye)

Süleyman KOÇ, (Cumhuriyet Üniversitesi, Tıp Fakültesi, Genel Cerrahi Anabilim Dalı, Sivas, Türkiye)

Esin BEYAN (Sağlık Bilimleri Üniversitesi, Keçiören Eğitim ve Araştırma Hastanesi, Dahiliye Kliniği, Ankara, Türkiye)

Osmangazi Tıp Dergisi

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Yıl: 2022 Cilt: 44 Sayı: 3 Sayfa Aralığı: 317 - 322 Metin Dili: İngilizce DOI: 10.20515/otd.997570 İndeks Tarihi: 07-09-2022

Comparison of APACHE II and Modified Charlson Index in Mortality Prediction in Patients at Medical Intensive Care Unit

Öz:

Acute Physiology and Chronic Health Evaluation II (APACHE II) and Modified Charlson Index (MCI) are used to predict the fatality in intensive care units (ICU). We aimed to investigate the difference between these scores in the prediction of fatality in the medical intensive care unit. Our study is important because in our literature overview, this study is one of the rare studies that compares these scoring systems. 108 ICU patients included. In all subjects APACHE II and MCI performed. Procalcitonin, C-reactive protein(CRP) levels of patients were recorded. Patients were then grouped according to mechanically ventilated or not; mortality happened or not. Statistically significance found in age(p<0.045), mechanical ventilation, procalcitonin, CRP and MCI (p<0.001) about mortality . MCI sensitivity and specifity were higher than APACHE II in %95 confidance interval. Area under curve in ROC analysis was CRP (0.728), Procalcitonin (0.719), MCI (0.686), APACHE II (0.665) respectively. Our study demonstrates that the Modified Charlson Index combined with procalcitonin and CRP can be used for predicting mortality in medical ICU as well as APACHE II

Anahtar Kelime: APACHE II Modified Charlson indeksi Dahili yoğun bakım ünitesi Prokalsitonin C-reaktif protein

Dahiliye Yoğun Bakım Hastalarında Mortalite Öngörüsünde APACHE II ve Modifiye Charlson İndeksinin Karşılaştırılması

Öz:

Acute Physiology and Chronic Health Evaluation II (APACHE II) ve Modifiye Charlson indeksi (MCI) yoğun bakımlarda mortalite öngörüsünde kullanılmaktadır. Biz bu skorlama sistemlerinin dahili yoğun bakımda yatan hastalardaki mortalite öngörüsünde aralarında fark olup olmadığını araştırdık. Çalışmamız dahili yoğun bakımda mortalite öngörüsünde bu iki skorlama sistemini karşılaştıran ilk çalışma olması açısından önemlidir. Çalışmaya 108 yoğun bakım hastası dahil edildi. Hastaların hepsine yatışlarının ardından APACHE II ve MCI hesaplandı. Hastaların prokalsitonin ve C-reaktif protein(CRP)seviyeleri kaydedildi. Hastalar mekanik ventilasyon uygulanıp uygulanmaması ve mortalite oluşup oluşmaması açısından gruplandırıldı. Mortalite açısından yaş(p<0,045), mekanik ventilasyon, prokalsitonin, CRP ve MCI istatiksel olarak anlamlı bulundu(p<0,001). MCI ‘nin % 95 güven aralığında sensitivitesi ve spesifitesi APACHE II ye göre daha yüksekti. ROC analizinde eğri altındaki alan ( Area under curve ) sırasıyla CRP için 0.728, Prokalsitonin için 0.719, MCI için 0.686, APACHE II için 0.665 di. Çalışmamız Modifiye Charlson indeksinin, procalcitonin ve CRP ile birlikte dahili yoğun bakımda mortaliteyi öngörmede APACHE II gibi kullanılabileceğini göstermiştir.

Anahtar Kelime: APACHE II Modified Charlson indeksi Dahili yoğun bakım ünitesi Prokalsitonin C-reaktif protein

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Bulur O, KAPLAN EFE F, IYNEM H, KOC S, Beyan E (2022). Comparison of APACHE II and Modified Charlson Index in Mortality Prediction in Patients at Medical Intensive Care Unit. , 317 - 322. 10.20515/otd.997570
Chicago	Bulur Oktay,KAPLAN EFE FATMA,IYNEM Hatice Kevser,KOC SULEYMAN,Beyan Esin Comparison of APACHE II and Modified Charlson Index in Mortality Prediction in Patients at Medical Intensive Care Unit. (2022): 317 - 322. 10.20515/otd.997570
MLA	Bulur Oktay,KAPLAN EFE FATMA,IYNEM Hatice Kevser,KOC SULEYMAN,Beyan Esin Comparison of APACHE II and Modified Charlson Index in Mortality Prediction in Patients at Medical Intensive Care Unit. , 2022, ss.317 - 322. 10.20515/otd.997570
AMA	Bulur O,KAPLAN EFE F,IYNEM H,KOC S,Beyan E Comparison of APACHE II and Modified Charlson Index in Mortality Prediction in Patients at Medical Intensive Care Unit. . 2022; 317 - 322. 10.20515/otd.997570
Vancouver	Bulur O,KAPLAN EFE F,IYNEM H,KOC S,Beyan E Comparison of APACHE II and Modified Charlson Index in Mortality Prediction in Patients at Medical Intensive Care Unit. . 2022; 317 - 322. 10.20515/otd.997570
IEEE	Bulur O,KAPLAN EFE F,IYNEM H,KOC S,Beyan E "Comparison of APACHE II and Modified Charlson Index in Mortality Prediction in Patients at Medical Intensive Care Unit." , ss.317 - 322, 2022. 10.20515/otd.997570
ISNAD	Bulur, Oktay vd. "Comparison of APACHE II and Modified Charlson Index in Mortality Prediction in Patients at Medical Intensive Care Unit". (2022), 317-322. https://doi.org/10.20515/otd.997570

APA	Bulur O, KAPLAN EFE F, IYNEM H, KOC S, Beyan E (2022). Comparison of APACHE II and Modified Charlson Index in Mortality Prediction in Patients at Medical Intensive Care Unit. Osmangazi Tıp Dergisi, 44(3), 317 - 322. 10.20515/otd.997570
Chicago	Bulur Oktay,KAPLAN EFE FATMA,IYNEM Hatice Kevser,KOC SULEYMAN,Beyan Esin Comparison of APACHE II and Modified Charlson Index in Mortality Prediction in Patients at Medical Intensive Care Unit. Osmangazi Tıp Dergisi 44, no.3 (2022): 317 - 322. 10.20515/otd.997570
MLA	Bulur Oktay,KAPLAN EFE FATMA,IYNEM Hatice Kevser,KOC SULEYMAN,Beyan Esin Comparison of APACHE II and Modified Charlson Index in Mortality Prediction in Patients at Medical Intensive Care Unit. Osmangazi Tıp Dergisi, vol.44, no.3, 2022, ss.317 - 322. 10.20515/otd.997570
AMA	Bulur O,KAPLAN EFE F,IYNEM H,KOC S,Beyan E Comparison of APACHE II and Modified Charlson Index in Mortality Prediction in Patients at Medical Intensive Care Unit. Osmangazi Tıp Dergisi. 2022; 44(3): 317 - 322. 10.20515/otd.997570
Vancouver	Bulur O,KAPLAN EFE F,IYNEM H,KOC S,Beyan E Comparison of APACHE II and Modified Charlson Index in Mortality Prediction in Patients at Medical Intensive Care Unit. Osmangazi Tıp Dergisi. 2022; 44(3): 317 - 322. 10.20515/otd.997570
IEEE	Bulur O,KAPLAN EFE F,IYNEM H,KOC S,Beyan E "Comparison of APACHE II and Modified Charlson Index in Mortality Prediction in Patients at Medical Intensive Care Unit." Osmangazi Tıp Dergisi, 44, ss.317 - 322, 2022. 10.20515/otd.997570
ISNAD	Bulur, Oktay vd. "Comparison of APACHE II and Modified Charlson Index in Mortality Prediction in Patients at Medical Intensive Care Unit". Osmangazi Tıp Dergisi 44/3 (2022), 317-322. https://doi.org/10.20515/otd.997570