The Effects of NLR on the Diagnosis and Pharmacological Management of Brain Abscesses

Hacıoğlu Kasım, Fatma Bahar; CALISKAN, Tezcan; Karaarslan, Numan; YILMAZ, İbrahim; ERSOZ, EMEL; DOGAN, Mustafa

doi:10.30565/medalanya.946066

The Effects of NLR on the Diagnosis and Pharmacological Management of Brain Abscesses

Tezcan Çalışkan, (Namık Kemal Üniversitesi, Tıp Fakültesi, Beyin Cerrahisi Anabilim Dalı, Tekirdağ, Türkiye)

İbrahim YILMAZ, (İstanbul Medipol Üniversitesi, Tıp Fakültesi, Tıbbi Farmakoloji Anabilim Dalı, İstanbul Türkiye)

Fatma Bahar Hacıoğlu Kasım, (Doktor İsmail Fehmi Cumalıoğlu Şehir Hastanesi, Radyoloji Klinikleri, Tekirdağ Türkiye)

EMEL ERSOZ, (Doktor İsmail Fehmi Cumalıoğlu Şehir Hastanesi, Nöroloji Klinikleri, Tekirdağ Türkiye)

Mustafa Doğan, (Namık Kemal Üniversitesi, Tıp Fakültesi, Enfeksiyon Hastalıkları Anabilim Dalı, Tekirdağ Türkiye)

NUMAN KARAARSLAN (Haliç Üniversitesi, Tıp Fakültesi, Nöroşirürji Anabilim Dalı, İstanbul, Türkiye)

Acta Medica Alanya

3 1

Yıl: 2021 Cilt: 5 Sayı: 3 Sayfa Aralığı: 308 - 316 Metin Dili: İngilizce DOI: 10.30565/medalanya.946066 İndeks Tarihi: 09-09-2022

The Effects of NLR on the Diagnosis and Pharmacological Management of Brain Abscesses

Öz:

Aim: The present study aims to examine the effectiveness of the neutrophil-tolymphocyte ratio in the treatment and diagnosis of patients with brain abscesses. Methods: In this retrospective study, radiological, neurological, and surgical data obtained from the medical records of healthy volunteers (n = 10) who presented to the hospital for check-ups and patients with brain abscesses who were treated (n = 10) were evaluated statistically. Alpha significance value was accepted as <0.05. Results: Comparisons between groups revealed that the erythrocyte sedimentation rate, C-reactive protein, leukocyte, and neutrophil values were statistically significant (P <0.05) while lymphocyte value was not statistically significant (P >0.05). The preoperative neutrophil-to-lymphocyte ratio in cases diagnosed with brain abscesses showed statistical significance compared to that in the healthy volunteers (P <0.05) and the neutrophil-to-lymphocyte ratio increased 3.31-fold in the study group compared to the healthy volunteers. Conclusion: A strong positive strong relationship between the neutrophil-tolymphocyte ratio and abscess size (r = 0.662; P = 0.037) was observed. An increased neutrophil-to-lymphocyte ratio may serve as an early warning signal of brain abscesses.

Anahtar Kelime: Antibiotic treatment brain abscess low-cost diagnosis method magnetic resonance image neutrophil-to-lymphocyte ratio

NLO’nun Beyin Apselerinin Tanı ve Farmakolojik Tedavi Yönetimine Etkileri

Öz:

Amaç: Bu makalede; beyin apsesi tanısı alan olgularda, nötrofil-lenfosit oranı (NLO)’nın, tanı ve tedavide önemli olup olmadığının incelenmesi amaçlandı. Metot: Retrospektif dizayna sahip araştırmada, hastaneye kontrol için gelen sağlıklı bireyler (n=10) ile beyin apsesi olan ve tedavi edilen olgular (n=10)’dan elde edilen radyolojik, nörolojik ve cerrahi veriler istatistiksel olarak değerlendirmeye alındı. Alfa anlamlılık değeri <0,05 olarak kabul edildi. Bulgular: Gruplar arası karşılaştırmalar sonucunda; eritrosit çökelme oranı (ESR), C-reaktif protein (CRP), lökosit (WBC) ve nötrofil (NEU) değerleri istatistiksel olarak anlamlı iken (P<0,05), lenfosit (LYMPH) değerinde istatistiksel olarak anlamlılık görülmedi (P>0,05). Sağlıklı bireylere oranla beyin apsesi tanısı alan olgulara ait preoperatif NLO değerlerinin istatistiksel olarak anlamlılık (P<0,05) gösterdiği ve NLO değerinin sağlıklı bireylere oranla yaklaşık 3,31 kat artış gösterdiği kaydedildi. Sonuç: NLO oranı ile abse boyutu arasında (r=0,662; P=0,037) pozitif yönde kuvvetli ilişki bulunmaktadır. Artış gösteren NLO, beyin apsesinin tanısında erken uyarı sinyali olarak hizmet edebilir.

Anahtar Kelime: Antibiyotik tedavisi beyin apsesi manyetik rezonans görüntüleme düşük maliyetli tanı metodu nötrofil-lenfosit oranı.

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	CALISKAN T, YILMAZ İ, Hacıoğlu Kasım F, ERSOZ E, DOGAN M, Karaarslan N (2021). The Effects of NLR on the Diagnosis and Pharmacological Management of Brain Abscesses. , 308 - 316. 10.30565/medalanya.946066
Chicago	CALISKAN Tezcan,YILMAZ İbrahim,Hacıoğlu Kasım Fatma Bahar,ERSOZ EMEL,DOGAN Mustafa,Karaarslan Numan The Effects of NLR on the Diagnosis and Pharmacological Management of Brain Abscesses. (2021): 308 - 316. 10.30565/medalanya.946066
MLA	CALISKAN Tezcan,YILMAZ İbrahim,Hacıoğlu Kasım Fatma Bahar,ERSOZ EMEL,DOGAN Mustafa,Karaarslan Numan The Effects of NLR on the Diagnosis and Pharmacological Management of Brain Abscesses. , 2021, ss.308 - 316. 10.30565/medalanya.946066
AMA	CALISKAN T,YILMAZ İ,Hacıoğlu Kasım F,ERSOZ E,DOGAN M,Karaarslan N The Effects of NLR on the Diagnosis and Pharmacological Management of Brain Abscesses. . 2021; 308 - 316. 10.30565/medalanya.946066
Vancouver	CALISKAN T,YILMAZ İ,Hacıoğlu Kasım F,ERSOZ E,DOGAN M,Karaarslan N The Effects of NLR on the Diagnosis and Pharmacological Management of Brain Abscesses. . 2021; 308 - 316. 10.30565/medalanya.946066
IEEE	CALISKAN T,YILMAZ İ,Hacıoğlu Kasım F,ERSOZ E,DOGAN M,Karaarslan N "The Effects of NLR on the Diagnosis and Pharmacological Management of Brain Abscesses." , ss.308 - 316, 2021. 10.30565/medalanya.946066
ISNAD	CALISKAN, Tezcan vd. "The Effects of NLR on the Diagnosis and Pharmacological Management of Brain Abscesses". (2021), 308-316. https://doi.org/10.30565/medalanya.946066

APA	CALISKAN T, YILMAZ İ, Hacıoğlu Kasım F, ERSOZ E, DOGAN M, Karaarslan N (2021). The Effects of NLR on the Diagnosis and Pharmacological Management of Brain Abscesses. Acta Medica Alanya, 5(3), 308 - 316. 10.30565/medalanya.946066
Chicago	CALISKAN Tezcan,YILMAZ İbrahim,Hacıoğlu Kasım Fatma Bahar,ERSOZ EMEL,DOGAN Mustafa,Karaarslan Numan The Effects of NLR on the Diagnosis and Pharmacological Management of Brain Abscesses. Acta Medica Alanya 5, no.3 (2021): 308 - 316. 10.30565/medalanya.946066
MLA	CALISKAN Tezcan,YILMAZ İbrahim,Hacıoğlu Kasım Fatma Bahar,ERSOZ EMEL,DOGAN Mustafa,Karaarslan Numan The Effects of NLR on the Diagnosis and Pharmacological Management of Brain Abscesses. Acta Medica Alanya, vol.5, no.3, 2021, ss.308 - 316. 10.30565/medalanya.946066
AMA	CALISKAN T,YILMAZ İ,Hacıoğlu Kasım F,ERSOZ E,DOGAN M,Karaarslan N The Effects of NLR on the Diagnosis and Pharmacological Management of Brain Abscesses. Acta Medica Alanya. 2021; 5(3): 308 - 316. 10.30565/medalanya.946066
Vancouver	CALISKAN T,YILMAZ İ,Hacıoğlu Kasım F,ERSOZ E,DOGAN M,Karaarslan N The Effects of NLR on the Diagnosis and Pharmacological Management of Brain Abscesses. Acta Medica Alanya. 2021; 5(3): 308 - 316. 10.30565/medalanya.946066
IEEE	CALISKAN T,YILMAZ İ,Hacıoğlu Kasım F,ERSOZ E,DOGAN M,Karaarslan N "The Effects of NLR on the Diagnosis and Pharmacological Management of Brain Abscesses." Acta Medica Alanya, 5, ss.308 - 316, 2021. 10.30565/medalanya.946066
ISNAD	CALISKAN, Tezcan vd. "The Effects of NLR on the Diagnosis and Pharmacological Management of Brain Abscesses". Acta Medica Alanya 5/3 (2021), 308-316. https://doi.org/10.30565/medalanya.946066