TY  - JOUR
TI  - High-risk obstructive sleep apnea is related to longer hospital stay in COVID-19 patients
AB  - BACKGROUND AND AIM: Obstructive sleep apnea (OSA), having an increased inflammatory state due to an imbalance between sympathetic and parasympathetic activity, intermittent hypoxia, and increased cytokines, may aggravate the immune response for COVID-19 infection. Our aim was to evaluate the effect of OSA upon inflammatory response and length of stay in patients with favorable outcomes. METHODS: Patients admitted to an outpatient clinic after being hospitalized for treatment of COVID-19 were included consecutively in this cross-sectional multicenter observational study. STOP-Bang Questionnaire and a cut-off value of 3 points were used to identify patients with a high risk of OSA. RESULTS: Study population consisted of 201 patients with a median STOP-Bang score of 2.0 (1.0–4.0) points. According to the cut-off value of 3 points, 94 (46.8%) patients were classified as high-risk OSA patients. High-risk OSA patients were older, had many comorbidities such as hypertension, coronary artery disease, and diabetes mellitus, had higher serum D-dimer, ferritin, Creactive protein, and procalcitonin measurements, and had a longer hospital stay. Possible risk factors associated with length of stay were age, lymphocyte count, and total STOP-Bang score. Multivariable analysis revealed that a 1 point increase in STOPBang score results in a 0.43 day longer hospital stay. CONCLUSIONS: Prevalence of OSA within COVID-19 patients with favorable outcomes is similar to the general population. However, the length of stay is related to the presence of high-risk OSA. Our study, therefore, suggests that OSA is related to delayed improvement of COVID-19 infection.
AU  - Ertem Cengiz, Arzu
AU  - Çetiner Bahçetepe, Dilek
AU  - AYDIN, Asena
AU  - Ursavas, Ahmet
AU  - Demirdöğen, Ezgi
AU  - Ediger, Dane
AU  - Aydin Guclu, Ozge
AU  - Gorek Dilektasli, Asli
AU  - Karadağ, Mehmet
AU  - Durmaz, Dilber
AU  - COŞKUN, FUNDA
AU  - Burgazlıoğlu, Başak
AU  - undefined, serap
AU  - TASBAS, ESİN
AU  - SENGOREN DİKİS, ÖZLEM
AU  - Sali, Mürsel
AU  - yavuz, zekiye
AU  - Beyeç, Melike
AU  - Zeytinoglu, Duygu
AU  - Acet Öztürk, Nilüfer Aylin
AU  - Uzaslan, Esra
AU  - Terzi, Orkun Eray
DO  - 10.14744/ejp.2022.9921
PY  - 2022
JO  - Eurasian Journal of Pulmonology
VL  - 24
IS  - 2
SN  - 2148-3620
SP  - 95
EP  - 100
DB  - TRDizin
UR  - http://search/yayin/detay/1120706
ER  -