In the 21st century, the fight against epidemic diseases continues at full speed. Control of epidemics is possible with individual and social measures as well as political regulations. It is extremely important for healthcare professionals to protect themselves from infection while providing care and treatment services to individuals affected by the epidemic. Personal protective equipment used for this purpose causes many problems in healthcare workers such as allergic contact dermatitis, pressure sores, hyperpigmentation, excessive sweating, and skin rash. In order to prevent long-term personal protective equipment from damaging the skin, it is recommended to clean the skin with saline or normal tap water, and to use preservatives such as barrier film after drying. After removing these equipment, cortisone creams can be applied if there is any damage to the skin. In order for the healthcare system to maintain its services effectively, healthcare team members must protect their own health. In this article, when healthcare team members use protective equipment; The points to be considered, the problems that may occur in the skin and strategies to prevent these problems were discussed by examining the relevant literature and research findings.