The Importance of Inflammatory Markers in Predicting Chronic Venous Insufficiency
Yıl: 2022 Cilt: 13 Sayı: 31 Sayfa Aralığı: 61 - 64 Metin Dili: İngilizce DOI: 10.5543/khd.2022.211825 İndeks Tarihi: 23-09-2022
The Importance of Inflammatory Markers in Predicting Chronic Venous Insufficiency
Öz: Objective: Chronic venous insufficiency can be missed unless it comes to mind. We need a simplified diagnosis of chronic venous insufficiency. This study is aimed to analyze the potential role of inflammatory markers like monocyte count/high-density lipoprotein cholesterol on the diagnosis of chronic venous insufficiency. Methods: This is a retrospective study. A total of 419 patients admitted to our clinics between September 1, 2019, and January 20, 2021, were included. Blood tests and venous Duplex ultrasound examinations applied to lower limb veins on the same day were studied. Monocyte count/high-density lipoprotein cholesterol was measured. A reflux time longer than 1 second in Duplex ultrasonography was considered venous insufficiency. The patients were divided into 2 groups according to the presence or absence of venous insufficiency. The relation between these results and the presence of venous insufficiency was examined. Results: When compared with the patients without venous insufficiency, monocyte count was higher (0.61 ± 0.18 vs. 0.55 ± 0.15 109 /L; P = .00) and high-density lipoprotein cholesterol was found to be lower (49 ± 9.1 vs. 53.4 ± 13.6 mg/dL; P = .02) in the patients with chronic venous insufficiency. The monocyte count to high-density lipoprotein cholesterol ratio was higher in the patients with chronic venous insufficiency (12.5 ± 5 vs. 10.9 ± 4; P = .005). According to multivariate regression analysis, monocyte count (95% CI: 1.003-1.035; P = .020) and monocyte count to high-density lipoprotein cholesterol ratio (95% CI: 1.017-1.154; P = .013) were independent risk factors for the occurrence of venous insufficiency. Conclusions: If the monocyte count to high-density lipoprotein cholesterol ratio is high, it may be predicted that this patient may have chronic venous insufficiency. This prediction may focus us on the lower extremity examination in clinical routine practice.
Anahtar Kelime: İnflamatuar Belirteçlerin Kronik Venöz Yetmezliğini Tahmin Ettirmedeki Önemi
Öz: Amaç: Kronik venöz yetmezlik akla gelmedikçe gözden kaçabilecek bir hastalıktır. Kronik inflamasyonun venöz kapakçıkların hasar görmesinde rol oynadığı düşünülmektedir. Bu çalışma, monosit sayısı ve yüksek yoğunluklu lipoprotein kolesterol oranı ve benzer diğer inflamatuar belirteçlerin kronik venöz yetmezlik tanısındaki potansiyel rolünü analiz etmeyi amaçlamaktadır. Yöntem: Çalışma retrospektif olarak dizayn edildi. Çalışmaya 1 Eylül 2019 ile 20 Ocak 2021 tarihleri arasında polikliniğe başvuran toplam 419 hasta dahil edildi. Hastaların kan testleri ve aynı gün yapılmış olan alt ekstremite venöz Doppler ultrason sonuçları değerlendirildi. Doppler ultrasonografide reflü zamanının bir saniyeden uzun olması venöz yetmezlik sayıldı. Venöz yetmezlik varlığına göre hastalar iki gruba ayrıldı. Kan tetkiklerinden elde edilen inflamatuar göstergeler ile venöz yetmezlik varlığı arasındaki ilişki incelendi. Bulgular: Kronik venöz yetmezliği olmayan hastalarla karşılaştırıldığında venöz yetmezliği olan hastalarda monosit sayısı daha yüksek (0,61 ± 0,18 ve 0,55 ± 0,15 109 / L; P = ,00) ve yüksek yoğunluklu lipoprotein kolesterol daha düşük (49 ± 9,1 ve 53,4 ± 13,6 mg/dL; P = ,02), monosit sayısının yüksek yoğunluklu lipoprotein kolesterole oranı daha yüksek saptandı (12,5 ± 5 ve 10,9 ± 4; P = ,005). Çok değişkenli regresyon analizine göre, monosit sayısı (%95 CI: 1,003-1,035; P = ,020) ve monosit sayısının yüksek yoğunluklu lipoprotein kolesterole oranı (%95 CI:1,017-1,154; P = ,013) venöz yetmezliğin ortaya çıkması için bağımsız risk faktörleriydi. Sonuç: Monosit sayısının yüksek yoğunluklu lipoprotein kolesterole oranı yüksekse diğer kronik inflamatuar hastalıklar gibi kronik venöz yetmezliği varlığını da düşünmeliyiz. Bu öngörü günlük pratikte bizi alt ekstremite muayenesine odaklayabilir.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Boyuk F, Demirkıran A, caliskan s, Altun S (2022). The Importance of Inflammatory Markers in Predicting Chronic Venous Insufficiency. , 61 - 64. 10.5543/khd.2022.211825 |
| Chicago | Boyuk Ferit,Demirkıran Aykut,caliskan serhat,Altun Senel The Importance of Inflammatory Markers in Predicting Chronic Venous Insufficiency. (2022): 61 - 64. 10.5543/khd.2022.211825 |
| MLA | Boyuk Ferit,Demirkıran Aykut,caliskan serhat,Altun Senel The Importance of Inflammatory Markers in Predicting Chronic Venous Insufficiency. , 2022, ss.61 - 64. 10.5543/khd.2022.211825 |
| AMA | Boyuk F,Demirkıran A,caliskan s,Altun S The Importance of Inflammatory Markers in Predicting Chronic Venous Insufficiency. . 2022; 61 - 64. 10.5543/khd.2022.211825 |
| Vancouver | Boyuk F,Demirkıran A,caliskan s,Altun S The Importance of Inflammatory Markers in Predicting Chronic Venous Insufficiency. . 2022; 61 - 64. 10.5543/khd.2022.211825 |
| IEEE | Boyuk F,Demirkıran A,caliskan s,Altun S "The Importance of Inflammatory Markers in Predicting Chronic Venous Insufficiency." , ss.61 - 64, 2022. 10.5543/khd.2022.211825 |
| ISNAD | Boyuk, Ferit vd. "The Importance of Inflammatory Markers in Predicting Chronic Venous Insufficiency". (2022), 61-64. https://doi.org/10.5543/khd.2022.211825 |
| APA | Boyuk F, Demirkıran A, caliskan s, Altun S (2022). The Importance of Inflammatory Markers in Predicting Chronic Venous Insufficiency. Kardiyovasküler Hemşirelik Dergisi, 13(31), 61 - 64. 10.5543/khd.2022.211825 |
| Chicago | Boyuk Ferit,Demirkıran Aykut,caliskan serhat,Altun Senel The Importance of Inflammatory Markers in Predicting Chronic Venous Insufficiency. Kardiyovasküler Hemşirelik Dergisi 13, no.31 (2022): 61 - 64. 10.5543/khd.2022.211825 |
| MLA | Boyuk Ferit,Demirkıran Aykut,caliskan serhat,Altun Senel The Importance of Inflammatory Markers in Predicting Chronic Venous Insufficiency. Kardiyovasküler Hemşirelik Dergisi, vol.13, no.31, 2022, ss.61 - 64. 10.5543/khd.2022.211825 |
| AMA | Boyuk F,Demirkıran A,caliskan s,Altun S The Importance of Inflammatory Markers in Predicting Chronic Venous Insufficiency. Kardiyovasküler Hemşirelik Dergisi. 2022; 13(31): 61 - 64. 10.5543/khd.2022.211825 |
| Vancouver | Boyuk F,Demirkıran A,caliskan s,Altun S The Importance of Inflammatory Markers in Predicting Chronic Venous Insufficiency. Kardiyovasküler Hemşirelik Dergisi. 2022; 13(31): 61 - 64. 10.5543/khd.2022.211825 |
| IEEE | Boyuk F,Demirkıran A,caliskan s,Altun S "The Importance of Inflammatory Markers in Predicting Chronic Venous Insufficiency." Kardiyovasküler Hemşirelik Dergisi, 13, ss.61 - 64, 2022. 10.5543/khd.2022.211825 |
| ISNAD | Boyuk, Ferit vd. "The Importance of Inflammatory Markers in Predicting Chronic Venous Insufficiency". Kardiyovasküler Hemşirelik Dergisi 13/31 (2022), 61-64. https://doi.org/10.5543/khd.2022.211825 |
