TY  - JOUR
TI  - Synthesis of novel pyrazoline derivatives and evaluation of their antimicrobial activity
AB  - In this study, new nine pyrazoline derivatives were synthesized from chalcone derivatives. The antimicrobial activity of nine pyrazoline derivatives to four standard bacterial strains (Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Enterococcus faecalis) and four standard yeast strains (Candida albicans, Candida glabrata, Candida parapsilosis, Candida tropicalis) was investigated by the microdilution method for in accordance with the Clinical and Laboratory Standards Institute (CLSI) standard, and the Minimal Inhibitory Concentration (MIC) values of these derivatives were determined. Among these derivatives; compounds 7 and 8 against bacterial strains and compounds 2 and 3 against yeast strains exhibited good antimicrobial activity.
AU  - TOK, FATİH
AU  - KOÇYİĞİT KAYMAKÇIOĞLU, Bedia
AU  - DOĞAN, Muhammed Oğuzhan
AU  - GÜRBÜZ, Burçak
DO  - 10.29228/jrp.238
PY  - 2022
JO  - Journal of research in pharmacy (online)
VL  - 26
IS  - 5
SN  - 2630-6344
SP  - 1453
EP  - 1460
DB  - TRDizin
UR  - http://search/yayin/detay/1125964
ER  -