Yıl: 2022 Cilt: 12 Sayı: 3 Sayfa Aralığı: 587 - 593 Metin Dili: İngilizce DOI: 10.33808/clinexphealthsci.943255 İndeks Tarihi: 03-10-2022

The Protective Effect of Rheum Ribes L., and Quercetin on Protein Carbonyl Levels Against Carbon Tetrachloride-Induced Liver and Kidney Damage in the Rats

Öz:
Objective: This study was designed to examine the potential protective effects of Rheum ribes L., and quercetin on protein carbonyl (PCO) in kidney and liver tissue, trace elements (Fe, Cu, Zn) and mineral (P) in serum samples in Wistar rats of carbon tetrachloride (CCl4)-induced oxidative damage. Methods: The 2, 4-dinitrophenylhydrazine (DNPH) method is the most reliable method widely used to measure carbonyl levels in proteins. In this study, the effect of Rheum ribes L. (Rr) and quercetin on protein carbonyl, trace elements (Fe, Cu, Zn) and mineral (P) levels against carbon tetrachloride (CCl4) mediated liver and kidney damage was investigated. For this purpose, 56 Wistar albino female rats weighing 200 ± 220 g were used. Groups were designed as: controls, 0.3 ml DMSO, 1 ml/kg olive oil, 1 ml/kg CCl4, 100 mg/kg Rr, 100 mg/kg quercetin, 100 mg/kg Rr+1 ml/kg CCl4 and 100 mg/kg quercetin+1 ml/kg CCl4 groups. Results: The results showed that the CCl4 group had significantly higher level of protein carbonyl (PCO) than the control, DMSO, olive oil, Rr and quercetin groups (p
Anahtar Kelime: carbon tetrachloride protein carbonyl quercetin rheum ribes L trace elements

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA BAKIR a, Ekin S, S, Oto G (2022). The Protective Effect of Rheum Ribes L., and Quercetin on Protein Carbonyl Levels Against Carbon Tetrachloride-Induced Liver and Kidney Damage in the Rats. , 587 - 593. 10.33808/clinexphealthsci.943255
Chicago BAKIR ahmet,Ekin Suat, Sevgi,Oto Gökhan The Protective Effect of Rheum Ribes L., and Quercetin on Protein Carbonyl Levels Against Carbon Tetrachloride-Induced Liver and Kidney Damage in the Rats. (2022): 587 - 593. 10.33808/clinexphealthsci.943255
MLA BAKIR ahmet,Ekin Suat, Sevgi,Oto Gökhan The Protective Effect of Rheum Ribes L., and Quercetin on Protein Carbonyl Levels Against Carbon Tetrachloride-Induced Liver and Kidney Damage in the Rats. , 2022, ss.587 - 593. 10.33808/clinexphealthsci.943255
AMA BAKIR a,Ekin S, S,Oto G The Protective Effect of Rheum Ribes L., and Quercetin on Protein Carbonyl Levels Against Carbon Tetrachloride-Induced Liver and Kidney Damage in the Rats. . 2022; 587 - 593. 10.33808/clinexphealthsci.943255
Vancouver BAKIR a,Ekin S, S,Oto G The Protective Effect of Rheum Ribes L., and Quercetin on Protein Carbonyl Levels Against Carbon Tetrachloride-Induced Liver and Kidney Damage in the Rats. . 2022; 587 - 593. 10.33808/clinexphealthsci.943255
IEEE BAKIR a,Ekin S, S,Oto G "The Protective Effect of Rheum Ribes L., and Quercetin on Protein Carbonyl Levels Against Carbon Tetrachloride-Induced Liver and Kidney Damage in the Rats." , ss.587 - 593, 2022. 10.33808/clinexphealthsci.943255
ISNAD BAKIR, ahmet vd. "The Protective Effect of Rheum Ribes L., and Quercetin on Protein Carbonyl Levels Against Carbon Tetrachloride-Induced Liver and Kidney Damage in the Rats". (2022), 587-593. https://doi.org/10.33808/clinexphealthsci.943255
APA BAKIR a, Ekin S, S, Oto G (2022). The Protective Effect of Rheum Ribes L., and Quercetin on Protein Carbonyl Levels Against Carbon Tetrachloride-Induced Liver and Kidney Damage in the Rats. Clinical and Experimental Health Sciences, 12(3), 587 - 593. 10.33808/clinexphealthsci.943255
Chicago BAKIR ahmet,Ekin Suat, Sevgi,Oto Gökhan The Protective Effect of Rheum Ribes L., and Quercetin on Protein Carbonyl Levels Against Carbon Tetrachloride-Induced Liver and Kidney Damage in the Rats. Clinical and Experimental Health Sciences 12, no.3 (2022): 587 - 593. 10.33808/clinexphealthsci.943255
MLA BAKIR ahmet,Ekin Suat, Sevgi,Oto Gökhan The Protective Effect of Rheum Ribes L., and Quercetin on Protein Carbonyl Levels Against Carbon Tetrachloride-Induced Liver and Kidney Damage in the Rats. Clinical and Experimental Health Sciences, vol.12, no.3, 2022, ss.587 - 593. 10.33808/clinexphealthsci.943255
AMA BAKIR a,Ekin S, S,Oto G The Protective Effect of Rheum Ribes L., and Quercetin on Protein Carbonyl Levels Against Carbon Tetrachloride-Induced Liver and Kidney Damage in the Rats. Clinical and Experimental Health Sciences. 2022; 12(3): 587 - 593. 10.33808/clinexphealthsci.943255
Vancouver BAKIR a,Ekin S, S,Oto G The Protective Effect of Rheum Ribes L., and Quercetin on Protein Carbonyl Levels Against Carbon Tetrachloride-Induced Liver and Kidney Damage in the Rats. Clinical and Experimental Health Sciences. 2022; 12(3): 587 - 593. 10.33808/clinexphealthsci.943255
IEEE BAKIR a,Ekin S, S,Oto G "The Protective Effect of Rheum Ribes L., and Quercetin on Protein Carbonyl Levels Against Carbon Tetrachloride-Induced Liver and Kidney Damage in the Rats." Clinical and Experimental Health Sciences, 12, ss.587 - 593, 2022. 10.33808/clinexphealthsci.943255
ISNAD BAKIR, ahmet vd. "The Protective Effect of Rheum Ribes L., and Quercetin on Protein Carbonyl Levels Against Carbon Tetrachloride-Induced Liver and Kidney Damage in the Rats". Clinical and Experimental Health Sciences 12/3 (2022), 587-593. https://doi.org/10.33808/clinexphealthsci.943255