Aim: The Coronavirus disease-2019 (COVID-19) pandemic has caused serious changes in health services in our country as well as all over the world. The most affected group includes those who will undergo surgery with an oncological diagnosis or who can be diagnosed with an oncological diagnosis. It is aimed to observe the changes in the operations with oncological diagnoses, which will require pathological examination in the operating room of our tertiary university hospital, in terms of demographics, surgical branch, duration of the operation and type of anesthesia in the first year of the pandemic. Materials and Methods: The retrospective scanning method was used to scan the surgical patient files of the patients who met the criteria (Retrospective cross-sectional study). Results: While the first 3 branches of our operating room with the highest number of cases did not change, there was a difference in the American Society of Anesthesiology (ASA) II-III scoring (p<0.05), neuraxial and trunk blocks (p<0.05) in which general anesthesia was applied alone as an anesthesia type or it was added. In addition, a change was observed in 13.3% of cases with oncological diagnosis and 32% in elective surgeries requiring pathological examination. Conclusion: In the COVID-19 pandemic, more expected cancellation rates did not occur by adapting to the “new normal”, but there were differences in ASA scores and anesthesia type during this period.