Introduction: Chordomas are rare, locally aggressive low-grade malignancies that develop from notochordal embryonic residues. They show a dual epithelial-mesenchymal differentiation. Chordomas preferentially occur in the sacrum. The head and neck localization is uncommon. Here we report chordomas of spheno-occipital, and cervical region diagnosed in our department and summarize clinicopathological characteristics of these cases. Methods: Retrospectively, the cases diagnosed as “chordoma” were reviewed from 2002 to 2021.Clinicopathological features of cases with a tumor at spheno-occipital, and cervical region were assessed. Results: Of 9 cases (4 males, 5 females) with a mean age of 53,4 (13–88 years), eight cases were diagnosed as conventional chordoma and one case as chondroid chordoma. Mean follow-up was 37 months (3-167 months). Recurrence was detected in 2 cases and distant metastasis was determined in one case. Discussion and Conclusion: Chordomas are resistant to chemotherapy and radiotherapy. Given the location and invasive nature of these tumors, complete resection is difficult. In the head and neck region, chordomas should be included in the differential diagnosis of tumors especially with myxoid characteristics.