Effects of stem cells and amniotic fluid on uterus and ovaries in a rat model of abdominal adhesions: a controlled study

Tümentemur, Gamze; Aygün, Elif Ganime

doi:10.4274/jtgga.galenos.2022.2022-1-14

Effects of stem cells and amniotic fluid on uterus and ovaries in a rat model of abdominal adhesions: a controlled study

Elif GANİME AYGÜN, (Acıbadem Mehmet Ali Aydınlar Üniversitesi, Atakent Hastanesi, Kadın Hastalıkları ve Doğum Kliniği, İstanbul, Türkiye)

Gamze TÜMENTEMUR (Acıbadem Mehmet Ali Aydınlar Üniversitesi Sağlık Hizmetleri Meslek Yüksekokulu, Anatomi Anabilim Dalı, İstanbul, Türkiye)

Journal of the Turkish-German Gynecological Association

4 0

Yıl: 2022 Cilt: 23 Sayı: 3 Sayfa Aralığı: 154 - 166 Metin Dili: İngilizce DOI: 10.4274/jtgga.galenos.2022.2022-1-14 İndeks Tarihi: 09-10-2022

Effects of stem cells and amniotic fluid on uterus and ovaries in a rat model of abdominal adhesions: a controlled study

Öz:

Objective: This study aimed to compare the effects of human umbilical cord mesenchymal stem cells (hUCMSCs), amniotic fluid (AF), and a combination of both on the uterus and ovaries in a rat model of abdominal adhesions. Material and Methods: This study was designed as a controlled study. Four groups, each consisting of six rats, were randomly formed. One group was designated as the control (CNT). hUCMSCs - applied (hUCSC), AF-applied (AMN), and a combination of both (hUCSC + AMN) were the experimental groups. All rats were given intraperitoneal talc powder to create adhesions. After 21 days, animals in experimental groups were further treated with hUCMSC, AF or a combination of these. Results: There was a statistically significant difference in primordial follicle count, endometrial gland number, and endometrial blood vessel count (p<0.05). AMN provided the best results in the endometrial vessel and primordial follicle count. The average endometrial gland count in AMN and hUCSC + AMN was similarly higher than CNT and hUCSC alone. Conclusion: There were significantly higher for counts for endometrial glands, endometrial blood vessels, and primordial follicles in the hUCSC, AMN and hUCSC + AMN groups compared to controls. Animals in the AMN group had the best result for endometrial vessel and highest primordial follicle count. (J Turk Ger Gynecol Assoc 2022; 23: 154-66)

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Aygün E, Tümentemur G (2022). Effects of stem cells and amniotic fluid on uterus and ovaries in a rat model of abdominal adhesions: a controlled study. , 154 - 166. 10.4274/jtgga.galenos.2022.2022-1-14
Chicago	Aygün Elif Ganime,Tümentemur Gamze Effects of stem cells and amniotic fluid on uterus and ovaries in a rat model of abdominal adhesions: a controlled study. (2022): 154 - 166. 10.4274/jtgga.galenos.2022.2022-1-14
MLA	Aygün Elif Ganime,Tümentemur Gamze Effects of stem cells and amniotic fluid on uterus and ovaries in a rat model of abdominal adhesions: a controlled study. , 2022, ss.154 - 166. 10.4274/jtgga.galenos.2022.2022-1-14
AMA	Aygün E,Tümentemur G Effects of stem cells and amniotic fluid on uterus and ovaries in a rat model of abdominal adhesions: a controlled study. . 2022; 154 - 166. 10.4274/jtgga.galenos.2022.2022-1-14
Vancouver	Aygün E,Tümentemur G Effects of stem cells and amniotic fluid on uterus and ovaries in a rat model of abdominal adhesions: a controlled study. . 2022; 154 - 166. 10.4274/jtgga.galenos.2022.2022-1-14
IEEE	Aygün E,Tümentemur G "Effects of stem cells and amniotic fluid on uterus and ovaries in a rat model of abdominal adhesions: a controlled study." , ss.154 - 166, 2022. 10.4274/jtgga.galenos.2022.2022-1-14
ISNAD	Aygün, Elif Ganime - Tümentemur, Gamze. "Effects of stem cells and amniotic fluid on uterus and ovaries in a rat model of abdominal adhesions: a controlled study". (2022), 154-166. https://doi.org/10.4274/jtgga.galenos.2022.2022-1-14

APA	Aygün E, Tümentemur G (2022). Effects of stem cells and amniotic fluid on uterus and ovaries in a rat model of abdominal adhesions: a controlled study. Journal of the Turkish-German Gynecological Association, 23(3), 154 - 166. 10.4274/jtgga.galenos.2022.2022-1-14
Chicago	Aygün Elif Ganime,Tümentemur Gamze Effects of stem cells and amniotic fluid on uterus and ovaries in a rat model of abdominal adhesions: a controlled study. Journal of the Turkish-German Gynecological Association 23, no.3 (2022): 154 - 166. 10.4274/jtgga.galenos.2022.2022-1-14
MLA	Aygün Elif Ganime,Tümentemur Gamze Effects of stem cells and amniotic fluid on uterus and ovaries in a rat model of abdominal adhesions: a controlled study. Journal of the Turkish-German Gynecological Association, vol.23, no.3, 2022, ss.154 - 166. 10.4274/jtgga.galenos.2022.2022-1-14
AMA	Aygün E,Tümentemur G Effects of stem cells and amniotic fluid on uterus and ovaries in a rat model of abdominal adhesions: a controlled study. Journal of the Turkish-German Gynecological Association. 2022; 23(3): 154 - 166. 10.4274/jtgga.galenos.2022.2022-1-14
Vancouver	Aygün E,Tümentemur G Effects of stem cells and amniotic fluid on uterus and ovaries in a rat model of abdominal adhesions: a controlled study. Journal of the Turkish-German Gynecological Association. 2022; 23(3): 154 - 166. 10.4274/jtgga.galenos.2022.2022-1-14
IEEE	Aygün E,Tümentemur G "Effects of stem cells and amniotic fluid on uterus and ovaries in a rat model of abdominal adhesions: a controlled study." Journal of the Turkish-German Gynecological Association, 23, ss.154 - 166, 2022. 10.4274/jtgga.galenos.2022.2022-1-14
ISNAD	Aygün, Elif Ganime - Tümentemur, Gamze. "Effects of stem cells and amniotic fluid on uterus and ovaries in a rat model of abdominal adhesions: a controlled study". Journal of the Turkish-German Gynecological Association 23/3 (2022), 154-166. https://doi.org/10.4274/jtgga.galenos.2022.2022-1-14