Venous-arterial CO2 to arterial-venous O2 content ratio in different shock types and correlation with hypoxia indicators

Akin, Sakir; van Steekelenburg, Anke; Guven, Goksel

doi:10.5578/tt.20229701

Venous-arterial CO2 to arterial-venous O2 content ratio in different shock types and correlation with hypoxia indicators

Göksel GÜVEN, (Hacettepe Üniversitesi Tıp Fakültesi Yoğun Bakım Anabilim Dalı, Ankara, Türkiye)

Anke van Steekelenburg, (Department of Intensive Care, Haga Hospital, The Hague, The Netherlands)

Sakir Akin (Department of Intensive Care, Haga Hospital, The Hague, The Netherlands)

Tüberküloz ve Toraks

5 1

Yıl: 2022 Cilt: 70 Sayı: 3 Sayfa Aralığı: 221 - 230 Metin Dili: İngilizce DOI: 10.5578/tt.20229701 İndeks Tarihi: 10-10-2022

Venous-arterial CO2 to arterial-venous O2 content ratio in different shock types and correlation with hypoxia indicators

Öz:

Venous-arterial CO2 to arterial-venous O2 content ratio in different shock types and correlation with hypoxia indicators Introduction: Shock is a generalized form of acute circulatory failure charac- terized by low tissue perfusion. If not recognized early, it highly increases patient morbidity and mortality. Central venous-arterial CO2 (Carbon dioxide) to arterial-central venous O2 (Oxygen) content ratio (Pcv-aCO2/Ca-cvO2) has been used for the early prediction of anaerobic metabolism in septic shock patients. However, knowledge about the usability of this ratio in cardiogenic shock is scarce. Materials and Methods: We retrospectively collected the data of patients admitted to our 18-bed intensive care unit (Haga Hospital, Department of Intensive Care, The Hague, The Netherlands) with a diagnosis of septic shock or cardiogenic shock in 2018. All patients who had undergone Swan-Ganz or Pulse index Continuous Cardiac Output device insertion were included in the study. The hemodynamic variables were recorded both at ICU admission and during catheterization. Results: Forty-six (n= 46) patients with a mean age of 62 ± 13 years and 52% female gender were enrolled in the study. The Acute Physiology and Chronic Health Evaluation IV (APACHE IV) score was 96 ± 39. Twenty-four patients had septic shock, and twenty-two were diagnosed with cardiogenic shock. Although Pcv-aCO2 (Central venous-arterial CO2) and ScvO2 (Central venous oxygen) were not found different between the cardiogenic and septic shock groups, the Pcv-aCO2/Ca-cvO2 ratio was significantly lower in patients with cardiogenic shock (p= 0.035). The Pcv-aCO2/Ca-cvO2 ratio had a weak cor- relation with ScvO2 (r= 0.21, p= 0.040). Pcv-aCO2 and ScvO2 showed nega- tive lower moderate correlation (r= -0.40, p= 0.030). Twenty patients [nine (19%) with cardiogenic shock, and eleven (23%) with septic shock] died during their ICU or hospital stay. Although Ca-cvO 2, Pcv-aCO2, and ScvO2 were not associated with mortality, a higher Pcv-aCO2/Ca-cvO2 ratio was associated with increased mortality (p= 0.035). Conclusion: The Pcv-aCO2/Ca-cvO2 ratio is a valuable hypoxia indicator in states of shock. However, cutoff levels should be identi- fied for different shock types.

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Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Guven G, van Steekelenburg A, Akin S (2022). Venous-arterial CO2 to arterial-venous O2 content ratio in different shock types and correlation with hypoxia indicators. , 221 - 230. 10.5578/tt.20229701
Chicago	Guven Goksel,van Steekelenburg Anke,Akin Sakir Venous-arterial CO2 to arterial-venous O2 content ratio in different shock types and correlation with hypoxia indicators. (2022): 221 - 230. 10.5578/tt.20229701
MLA	Guven Goksel,van Steekelenburg Anke,Akin Sakir Venous-arterial CO2 to arterial-venous O2 content ratio in different shock types and correlation with hypoxia indicators. , 2022, ss.221 - 230. 10.5578/tt.20229701
AMA	Guven G,van Steekelenburg A,Akin S Venous-arterial CO2 to arterial-venous O2 content ratio in different shock types and correlation with hypoxia indicators. . 2022; 221 - 230. 10.5578/tt.20229701
Vancouver	Guven G,van Steekelenburg A,Akin S Venous-arterial CO2 to arterial-venous O2 content ratio in different shock types and correlation with hypoxia indicators. . 2022; 221 - 230. 10.5578/tt.20229701
IEEE	Guven G,van Steekelenburg A,Akin S "Venous-arterial CO2 to arterial-venous O2 content ratio in different shock types and correlation with hypoxia indicators." , ss.221 - 230, 2022. 10.5578/tt.20229701
ISNAD	Guven, Goksel vd. "Venous-arterial CO2 to arterial-venous O2 content ratio in different shock types and correlation with hypoxia indicators". (2022), 221-230. https://doi.org/10.5578/tt.20229701

APA	Guven G, van Steekelenburg A, Akin S (2022). Venous-arterial CO2 to arterial-venous O2 content ratio in different shock types and correlation with hypoxia indicators. Tüberküloz ve Toraks, 70(3), 221 - 230. 10.5578/tt.20229701
Chicago	Guven Goksel,van Steekelenburg Anke,Akin Sakir Venous-arterial CO2 to arterial-venous O2 content ratio in different shock types and correlation with hypoxia indicators. Tüberküloz ve Toraks 70, no.3 (2022): 221 - 230. 10.5578/tt.20229701
MLA	Guven Goksel,van Steekelenburg Anke,Akin Sakir Venous-arterial CO2 to arterial-venous O2 content ratio in different shock types and correlation with hypoxia indicators. Tüberküloz ve Toraks, vol.70, no.3, 2022, ss.221 - 230. 10.5578/tt.20229701
AMA	Guven G,van Steekelenburg A,Akin S Venous-arterial CO2 to arterial-venous O2 content ratio in different shock types and correlation with hypoxia indicators. Tüberküloz ve Toraks. 2022; 70(3): 221 - 230. 10.5578/tt.20229701
Vancouver	Guven G,van Steekelenburg A,Akin S Venous-arterial CO2 to arterial-venous O2 content ratio in different shock types and correlation with hypoxia indicators. Tüberküloz ve Toraks. 2022; 70(3): 221 - 230. 10.5578/tt.20229701
IEEE	Guven G,van Steekelenburg A,Akin S "Venous-arterial CO2 to arterial-venous O2 content ratio in different shock types and correlation with hypoxia indicators." Tüberküloz ve Toraks, 70, ss.221 - 230, 2022. 10.5578/tt.20229701
ISNAD	Guven, Goksel vd. "Venous-arterial CO2 to arterial-venous O2 content ratio in different shock types and correlation with hypoxia indicators". Tüberküloz ve Toraks 70/3 (2022), 221-230. https://doi.org/10.5578/tt.20229701