TY  - JOUR
TI  - Sepsis and Septic Shock: Outcomes in Elderly and  Very Elderly Intensive Care Patients
AB  - Objective: The relationship between age and the development and outcome of  sepsis and septic shock is unclear, especially in adults. There are few studies about the incidence,  prognosis and mortality rates of sepsis in elderly and very elderly patients. In this study, we aimed  to determine the effect of age on the outcome of sepsis and septic shock in elderly and very elderly  intensive care unit (ICU) patients. Materials and Methods: This study was a retrospective observational study conducted in our  medical ICU. Two hundred elderly and very elderly patients with sepsis and septic shock were  included in this study. Results: The mortality rate related to sepsis and septic shock was 61.5% (123 patients). The  most common site of infection was lung (56.5%, 113 patients), followed by urinary tract (35%, 70  patients). There was no significant difference between the elderly (61.2%, 82 patients) and the  very elderly (62.1%, 41 patients) patients in terms of ICU mortality related to sepsis and septic  shock (p>0.05). Sequential Organ Failure Assessment score on ICU admission [1.195 odds ratio  (OR) and 1.052-1.358 95% confidence interval (CI), p=0.006], requirement of invasive mechanical  ventilation on ICU admission (4.330 OR and 1.529-12.258 95% CI, p=0.006), renal impairment at  the end of the ICU follow-up (6.457 OR and 1.795-23.233 95% CI, p=0.004) and the disability to  feed orally in ICU (0.064 OR and 0.018-0.226 95% CI, p=0.0001) were found as independent risk  factors for ICU mortality. Conclusion: According to our study, there was no significant difference between the elderly and  the very elderly ICU patients with sepsis and septic shock in terms of mortality rates. However, the  presence of organ damage during ICU admission and the development of complications during ICU  stay significantly affected mortality.
AU  - YAPAÖZ, melda
AU  - Candemir, Burcu
AU  - Aygencel, Gulbin
AU  - İnci, Kamil
DO  - 10.4274/tybd.galenos.2019.41275
PY  - 2022
JO  - Türk Yoğun Bakım Dergisi
VL  - 20
IS  - 1
SN  - 2602-2974
SP  - 9
EP  - 16
DB  - TRDizin
UR  - http://search/yayin/detay/1131943
ER  -