TY  - JOUR
TI  - Comparison of Stroke Volume Variation-based goal-directed Therapy  Versus Standard Fluid Therapy in Patients Undergoing Head and Neck  Surgery: A Randomized Controlled Study
AB  - Background: Perioperative fluid therapy is used to avoid dehydration and hypovolemia. Optimum perioperative fluid administration may improve postoperative outcomes after major surgery, and the optimal strategy remains controversial and uncertain.  Aims: The primary outcome was the total amount of intraoperative  fluids given between perioperative goal-directed fluid therapy (GDFT)  guided by a hemodynamic monitoring system and standard fluid  therapy based on “mean arterial pressure-diuresis” data in patients  undergoing head and neck surgery. The secondary outcomes were the  hemodynamics and laboratory variables, postoperative complications,  length of mechanical ventilation, intensive care unit and hospital stay.  Study Design: A randomized controlled study Methods: Sixty patients were scheduled and randomized into two  groups of 30 patients each: in the study group, an arterial pressure  catheter was inserted and connected to the FloTrac system, whereas  in the control group, an arterial pressure catheter was inserted and  integrated into the hemodynamic monitoring system with a special  transducer. The control group had fluids administered at the discretion  of the anesthesiologist according to the mean arterial pressure >65  mmHg and diuresis >0.5 ml/kg/h. In the study group, fluid management  was administered to achieve a target value of ≤13% through the stroke  volume variation.  Results: The total amounts of fluid in the intraoperative period  were different between the groups, with the study group receiving  significantly more fluids (P = 0.0455). The length of hospital stay was  significantly longer in the study group than in the control group (P =  0.012), but prolonged oxygen demand was significantly more frequent  in the control group than in the study group (P = 0.017). No difference  was found in hemodynamics, lactate kinetics, and vasoactive agent  requirements.  Conclusion: The standard fluid therapy guided by conventional  circulatory parameters appears sufficient for patients with low-to moderate risk during head and neck surgery.
AU  - UZUNTÜRK, Cansu
AU  - TURKUT, Nuray
AU  - Çamcı, Emre
AU  - Canbolat, Nur
AU  - Sen, Comert
AU  - Altun, Demet
DO  - 10.4274/balkanmedj.galenos.2022.2022-1-88
PY  - 2022
JO  - Balkan Medical Journal
VL  - 39
IS  - 5
SN  - 2146-3123
SP  - 351
EP  - 357
DB  - TRDizin
UR  - http://search/yayin/detay/1132453
ER  -