Investigation of the Change in the Incidence of Neural Tube Defects in the Eastern Black Sea Region of Turkey by Years and its Relationship with Folic Acid Use: A Case-control Study

Demir, Omer; şal, hidayet; TOPBAS, MURAT; özalp, miraç

doi:10.4274/haseki.galenos.2022.8245

Investigation of the Change in the Incidence of Neural Tube Defects in the Eastern Black Sea Region of Turkey by Years and its Relationship with Folic Acid Use: A Case-control Study

Omer DEMIR, (Karadeniz Teknik Üniversitesi Tıp Fakültesi Kadın Hastalıkları ve Doğum Anabilim Dalı, Trabzon, Türkiye)

Hidayet ŞAL, (Araklı Bayram Halil Devlet Hastanesi, Kadın Hastalıkları ve Doğum Kliniği, Trabzon, Türkiye)

Miraç ÖZALP, (Türkiye Sağlık Bilimleri Üniversitesi, İstanbul Prof. Dr. Cemil Taşçıoğlu Şehir Hastanesi, Kadın Hastalıkları ve Doğum Kliniği, İstanbul, Türkiye)

MURAT TOPBAŞ (Karadeniz Teknik Üniversitesi Tıp Fakültesi, Halk Sağlığı Anabilim Dalı, Trabzon, Türkiye)

Haseki Tıp Bülteni

6 4

Yıl: 2022 Cilt: 60 Sayı: 4 Sayfa Aralığı: 303 - 309 Metin Dili: İngilizce DOI: 10.4274/haseki.galenos.2022.8245 İndeks Tarihi: 16-10-2022

Investigation of the Change in the Incidence of Neural Tube Defects in the Eastern Black Sea Region of Turkey by Years and its Relationship with Folic Acid Use: A Case-control Study

Öz:

Aim: This study aimed to determine the change in neural tube defects (NTD) incidence in Trabzon, a province of the Eastern Black Sea region, and evaluate the efficiency of folic acid use on NTD. Methods: The present study was a retrospective case-control study. The case group of the study consisted of those diagnosed with fetal NTD in the intrauterine period between 2015 and 2020. The control group were selected by matching the ages in the case group with ± two standardized years. The total number of births in the province was obtained from the Turkish Statistical Institute data, and the NTD incidence was determined accordingly. Results: Between the aforementioned years, the number of cases who had NTD-complicated pregnancies and were delivered in our clinic was 88. When the use of folic acid before and in the first trimester of pregnancy was compared, a statistically significant difference was determined between the groups (p<0.001). The use of folic acid during pregnancy was similar in both groups (p=1). Conclusion: Neural tube defects is a preventable condition by using folic acid before and during the first trimester of pregnancy. Hence, the importance of using folic acid in family planning and prenatal counseling should not be forgotten.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Demir O, şal h, özalp m, TOPBAS M (2022). Investigation of the Change in the Incidence of Neural Tube Defects in the Eastern Black Sea Region of Turkey by Years and its Relationship with Folic Acid Use: A Case-control Study. , 303 - 309. 10.4274/haseki.galenos.2022.8245
Chicago	Demir Omer,şal hidayet,özalp miraç,TOPBAS MURAT Investigation of the Change in the Incidence of Neural Tube Defects in the Eastern Black Sea Region of Turkey by Years and its Relationship with Folic Acid Use: A Case-control Study. (2022): 303 - 309. 10.4274/haseki.galenos.2022.8245
MLA	Demir Omer,şal hidayet,özalp miraç,TOPBAS MURAT Investigation of the Change in the Incidence of Neural Tube Defects in the Eastern Black Sea Region of Turkey by Years and its Relationship with Folic Acid Use: A Case-control Study. , 2022, ss.303 - 309. 10.4274/haseki.galenos.2022.8245
AMA	Demir O,şal h,özalp m,TOPBAS M Investigation of the Change in the Incidence of Neural Tube Defects in the Eastern Black Sea Region of Turkey by Years and its Relationship with Folic Acid Use: A Case-control Study. . 2022; 303 - 309. 10.4274/haseki.galenos.2022.8245
Vancouver	Demir O,şal h,özalp m,TOPBAS M Investigation of the Change in the Incidence of Neural Tube Defects in the Eastern Black Sea Region of Turkey by Years and its Relationship with Folic Acid Use: A Case-control Study. . 2022; 303 - 309. 10.4274/haseki.galenos.2022.8245
IEEE	Demir O,şal h,özalp m,TOPBAS M "Investigation of the Change in the Incidence of Neural Tube Defects in the Eastern Black Sea Region of Turkey by Years and its Relationship with Folic Acid Use: A Case-control Study." , ss.303 - 309, 2022. 10.4274/haseki.galenos.2022.8245
ISNAD	Demir, Omer vd. "Investigation of the Change in the Incidence of Neural Tube Defects in the Eastern Black Sea Region of Turkey by Years and its Relationship with Folic Acid Use: A Case-control Study". (2022), 303-309. https://doi.org/10.4274/haseki.galenos.2022.8245

APA	Demir O, şal h, özalp m, TOPBAS M (2022). Investigation of the Change in the Incidence of Neural Tube Defects in the Eastern Black Sea Region of Turkey by Years and its Relationship with Folic Acid Use: A Case-control Study. Haseki Tıp Bülteni, 60(4), 303 - 309. 10.4274/haseki.galenos.2022.8245
Chicago	Demir Omer,şal hidayet,özalp miraç,TOPBAS MURAT Investigation of the Change in the Incidence of Neural Tube Defects in the Eastern Black Sea Region of Turkey by Years and its Relationship with Folic Acid Use: A Case-control Study. Haseki Tıp Bülteni 60, no.4 (2022): 303 - 309. 10.4274/haseki.galenos.2022.8245
MLA	Demir Omer,şal hidayet,özalp miraç,TOPBAS MURAT Investigation of the Change in the Incidence of Neural Tube Defects in the Eastern Black Sea Region of Turkey by Years and its Relationship with Folic Acid Use: A Case-control Study. Haseki Tıp Bülteni, vol.60, no.4, 2022, ss.303 - 309. 10.4274/haseki.galenos.2022.8245
AMA	Demir O,şal h,özalp m,TOPBAS M Investigation of the Change in the Incidence of Neural Tube Defects in the Eastern Black Sea Region of Turkey by Years and its Relationship with Folic Acid Use: A Case-control Study. Haseki Tıp Bülteni. 2022; 60(4): 303 - 309. 10.4274/haseki.galenos.2022.8245
Vancouver	Demir O,şal h,özalp m,TOPBAS M Investigation of the Change in the Incidence of Neural Tube Defects in the Eastern Black Sea Region of Turkey by Years and its Relationship with Folic Acid Use: A Case-control Study. Haseki Tıp Bülteni. 2022; 60(4): 303 - 309. 10.4274/haseki.galenos.2022.8245
IEEE	Demir O,şal h,özalp m,TOPBAS M "Investigation of the Change in the Incidence of Neural Tube Defects in the Eastern Black Sea Region of Turkey by Years and its Relationship with Folic Acid Use: A Case-control Study." Haseki Tıp Bülteni, 60, ss.303 - 309, 2022. 10.4274/haseki.galenos.2022.8245
ISNAD	Demir, Omer vd. "Investigation of the Change in the Incidence of Neural Tube Defects in the Eastern Black Sea Region of Turkey by Years and its Relationship with Folic Acid Use: A Case-control Study". Haseki Tıp Bülteni 60/4 (2022), 303-309. https://doi.org/10.4274/haseki.galenos.2022.8245