Associations Between c.2832A > G Polymorphism of CAST Gene and Meat Tenderness in Cattle: A Meta-Analysis
Yıl: 2022 Cilt: 28 Sayı: 5 Sayfa Aralığı: 613 - 620 Metin Dili: İngilizce DOI: 10.9775/kvfd.2022.27770 İndeks Tarihi: 22-10-2022
Associations Between c.2832A > G Polymorphism of CAST Gene and Meat Tenderness in Cattle: A Meta-Analysis
Öz: Genes or genetic markers related to meat quality have been studied for many years. The CAST gene is one candidate gene affecting meat tenderness in cattle. This meta-analysis aimed to examine the association of c.2832A>G polymorphism of the CAST gene and meat tenderness in cattle. According to the determined criteria, 17 studies were included in the meta-analysis, and pooled ratios of allele and genotype frequencies were calculated. In addition, the combined Warner-Braztler Shear Force values were calculated for three studies that reported these values according to genotypes for the meat tenderness feature. Heterogeneity between studies and publication bias were also tested. As a result of the meta-analysis, pooled ratios of AA, AG, and GG genotypes are 0.578, 0.342, and 0.080; pooled ratios of A and G alleles are 0.777 and 0.223. The highest pooled ratios were obtained for AA genotype and A allele. The combined Warner-Braztler shear force values were calculated as 3.707, 3.893, and 5.137 kilogram-force for AA, AG, and GG genotypes. The highest mean shear force value was obtained for the GG genotype. In conclusion, the meta-analysis results examined the relationship between c.2832A>G polymorphism of the CAST gene and meat tenderness were closer to the population parameter. This study may improve genetic selection and provide new strategies to increase meat quality in cattle.
Anahtar Kelime: CAST Geninin c.2832A > G Polimorfizmi ile Sığırlarda Et Gevrekliği Arasındaki İlişki: Bir Meta-Analizi
Öz: Et kalitesiyle ilgili genler veya genetic belirteçler uzun yıllardır araştırılmaktadır. CAST geni, sığırlarda et gevrekliğini etkileyen bir aday gendir. Bu meta analizi, sığırlarda CAST geninin c.2832A>G polimorfizmi ile et gevrekliği arasındaki ilişkiyi incelemeyi amaçlamıştır. Belirlenen kriterlere göre, 17 çalışma meta analize dahil edilmiş ve allel ve genotip frekansların birleştirilmiş oranları hesaplanmıştır. Bunun yanında, etin gevreklik özelliği için Warner-Braztler kesme kuvveti değerlerini genotiplere göre veren üç çalışmanın sonucu için birleştirilmiş kesme kuvveti değeri hesaplanmıştır. Çalışmalar arası heterojenlik ve yayın yanlılığı da test edilmiştir. Meta-analizi sonucunda AA, AG ve GG genotiplerinin birleştirilmiş oranları 0.578, 0.342 ve 0.080; A ve G alellerinin birleştirilmiş oranları 0.777 ve 0.223 olarak elde edilmiştir. En yüksek birleştirilmiş oranlar AA genotipi ve A alleli için elde edilmiştir. Birleştirilmiş Warner-Braztler kesme kuvveti değerleri AA, AG ve GG genotipleri için sırasıyla 3.707, 3.893 ve 5.137 kilogram kuvvet olarak hesaplanmıştır. En yüksek ortalama kesme kuvveti değeri GG genotipi için elde edilmiştir. Sonuç olarak, CAST geninin c.2832A>G polimorfizmi ile et gevrekliği arasındaki ilişkinin incelendiği meta-analiz sonuçları populasyon parametresine yakın bulunmuştur. Bu çalışma sığırlarda genetik seçimi geliştirmek ve et kalitesini arttırmak için yeni stratejiler sağlayabilir.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Uzabacı E, DİNÇEL D (2022). Associations Between c.2832A > G Polymorphism of CAST Gene and Meat Tenderness in Cattle: A Meta-Analysis. , 613 - 620. 10.9775/kvfd.2022.27770 |
| Chicago | Uzabacı Ender,DİNÇEL Deniz Associations Between c.2832A > G Polymorphism of CAST Gene and Meat Tenderness in Cattle: A Meta-Analysis. (2022): 613 - 620. 10.9775/kvfd.2022.27770 |
| MLA | Uzabacı Ender,DİNÇEL Deniz Associations Between c.2832A > G Polymorphism of CAST Gene and Meat Tenderness in Cattle: A Meta-Analysis. , 2022, ss.613 - 620. 10.9775/kvfd.2022.27770 |
| AMA | Uzabacı E,DİNÇEL D Associations Between c.2832A > G Polymorphism of CAST Gene and Meat Tenderness in Cattle: A Meta-Analysis. . 2022; 613 - 620. 10.9775/kvfd.2022.27770 |
| Vancouver | Uzabacı E,DİNÇEL D Associations Between c.2832A > G Polymorphism of CAST Gene and Meat Tenderness in Cattle: A Meta-Analysis. . 2022; 613 - 620. 10.9775/kvfd.2022.27770 |
| IEEE | Uzabacı E,DİNÇEL D "Associations Between c.2832A > G Polymorphism of CAST Gene and Meat Tenderness in Cattle: A Meta-Analysis." , ss.613 - 620, 2022. 10.9775/kvfd.2022.27770 |
| ISNAD | Uzabacı, Ender - DİNÇEL, Deniz. "Associations Between c.2832A > G Polymorphism of CAST Gene and Meat Tenderness in Cattle: A Meta-Analysis". (2022), 613-620. https://doi.org/10.9775/kvfd.2022.27770 |
| APA | Uzabacı E, DİNÇEL D (2022). Associations Between c.2832A > G Polymorphism of CAST Gene and Meat Tenderness in Cattle: A Meta-Analysis. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 28(5), 613 - 620. 10.9775/kvfd.2022.27770 |
| Chicago | Uzabacı Ender,DİNÇEL Deniz Associations Between c.2832A > G Polymorphism of CAST Gene and Meat Tenderness in Cattle: A Meta-Analysis. Kafkas Üniversitesi Veteriner Fakültesi Dergisi 28, no.5 (2022): 613 - 620. 10.9775/kvfd.2022.27770 |
| MLA | Uzabacı Ender,DİNÇEL Deniz Associations Between c.2832A > G Polymorphism of CAST Gene and Meat Tenderness in Cattle: A Meta-Analysis. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, vol.28, no.5, 2022, ss.613 - 620. 10.9775/kvfd.2022.27770 |
| AMA | Uzabacı E,DİNÇEL D Associations Between c.2832A > G Polymorphism of CAST Gene and Meat Tenderness in Cattle: A Meta-Analysis. Kafkas Üniversitesi Veteriner Fakültesi Dergisi. 2022; 28(5): 613 - 620. 10.9775/kvfd.2022.27770 |
| Vancouver | Uzabacı E,DİNÇEL D Associations Between c.2832A > G Polymorphism of CAST Gene and Meat Tenderness in Cattle: A Meta-Analysis. Kafkas Üniversitesi Veteriner Fakültesi Dergisi. 2022; 28(5): 613 - 620. 10.9775/kvfd.2022.27770 |
| IEEE | Uzabacı E,DİNÇEL D "Associations Between c.2832A > G Polymorphism of CAST Gene and Meat Tenderness in Cattle: A Meta-Analysis." Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 28, ss.613 - 620, 2022. 10.9775/kvfd.2022.27770 |
| ISNAD | Uzabacı, Ender - DİNÇEL, Deniz. "Associations Between c.2832A > G Polymorphism of CAST Gene and Meat Tenderness in Cattle: A Meta-Analysis". Kafkas Üniversitesi Veteriner Fakültesi Dergisi 28/5 (2022), 613-620. https://doi.org/10.9775/kvfd.2022.27770 |
